Neomycin Sulfate (Streptomyces fradiae waksman)

Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes. Inhibitor of phospholipase C due to binding to inositol phospholipids. Neomycin inhibits phosphatidylcholine-phospholipase D activity. Blocks voltage sensitive Ca2+ channels without affecting Na+/Ca2+ antiporter in nerve cells. CAS No: 1405-10-3, Molecular Formula: C23H46N6O133H2SO4, Molecular Weight: 908.9, Appearance: White to light yellow crystaline powder, Potency: >600 IU/mg (dry basis), pH: 5.0-7.5, Identity: Conforms to USP reference, Loss on Drying: <8%, Solubility: Alcohol: Insoluble, DMSO: Insoluble, Water: 143mg/ml (200.63 mM)