Unacylated Ghrelin (human) Easy Sampling EIA Kit

Unacylated Ghrelin (human) Easy Sampling EIA Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay501190-96 96 wells -

6 - 10 Werktage*

1.056,00 €
 
This EIA so called Easy Sampling EIA kit works with any sample collected on any kind of protease... mehr
Produktinformationen "Unacylated Ghrelin (human) Easy Sampling EIA Kit"
This EIA so called Easy Sampling EIA kit works with any sample collected on any kind of protease inhibitors, without extraction but a simple dilution. Ghrelin discovered in 1999, is fast becoming an endocrinology target of the millennium. Ghrelin, identified in rat stomach as an endogenous ligand for the GH secretagogue receptor, is mainly produced in stomach, but has been demonstrated in many other organs. In addition to GH-releasing properties and its orexant action, Ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin), acidic secretion, cardiovascular action, antiproliferative effects, pancreatic and glucose metabolism function, sleep... Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into Ghrelin, 28 amino acids (human). Before being secreted, this peptide is octanoylated at Ser 3 by GOAT (Ghrelin Octanoyl Acyl Transferase). This step is essential for biological activity making GOAT a perfect target for drugs in feeding behaviour. Interestingly, the potential therapeutic importance of this hormone is not restricted to regulation of food intake but also in cachexia (related to cancer treatment, anorexia nervosa or ischemia) gastric motility and may be involved in osteoporosis, somatopause, infertility and ovulation induction, neurological disorders (Alcoholism, Post Traumatic Stress disorders...) and cardiovascular diseases. [Bertin Catalog No. A05319.96 wells]Synonyms: Unacylated Ghrelin (human) Easy Sampling ELISA.
Schlagworte: Unacylated Ghrelin (human) Easy Sampling ELISA
Hersteller: Cayman Chemical
Hersteller-Nr: 501190

Eigenschaften

Anwendung: ELISA
Spezies-Reaktivität: human
Immunogen: Unacylated Ghrelin (rat) 200%|Unacylated Ghrelin (dog) 150%|Acylated Ghrelin (dog) 19%|Acylated Ghrelin (human) <5%|Acylated Ghrelin (mouse,rat) <5%|CRF (human, rat) <0.001%|Ghrelin (1-11) (rat) <0.001%|Ghrelin (1-14) (human) <0.001%|Ghrelin (17-28) (human, rat) <0.001%|GHRF (human) <0.001%|Glucagon (human, rat) <0.001%|Insulin (human) <0.001%|Leptin (human) <0.001%|Motiline <0.001%|Somatostatine <0.001%
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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