Human TGFBR2 ELISA Kit

Human TGFBR2 ELISA Kit
+ Gratis T-Shirt
Aktion:

Sichern Sie sich ein gratis "Stronger Bands" T-Shirt zu jeder Rockland-Bestellung >300 €.

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
KOA0781 1 kit - -

1 - 9 Werktage

673,00 €
 
Natural and recombinant human TGFBR2. There is no detectable cross-reactivity with other relevant... mehr
Produktinformationen "Human TGFBR2 ELISA Kit"
Natural and recombinant human TGFBR2. There is no detectable cross-reactivity with other relevant proteins. Protein function: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFRB1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non- canonical, SMAD-independent TGF-beta signaling pathways. [The UniProt Consortium]
Schlagworte: TGFBR2, TGFR-2, TbetaR-II, EC=2.7.11.30, TGF-beta receptor type-2, TGF-beta type II receptor, TGF-beta receptor type II, Transforming growth factor-beta receptor type II
Hersteller: Rockland Immunochemicals
Hersteller-Nr: KOA0781

Eigenschaften

Anwendung: ELISA
Wirt: Human
Reaktivität: Human
Immunogen: Expression system for standard: NSO, Immunogen sequence: I24-D159
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Human TGFBR2 ELISA Kit"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Hier folgen Informationen zur Produktreferenz. mehr
Zuletzt angesehen