Zu "K04388" wurden 110 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
![TGF-beta RII/TGFBR2 mFc Chimera[Biotin], Avi, Human](https://www.biomol.com/media/image/fd/a6/83/GSC-Z04620-100_200x200.png "TGF-beta RII/TGFBR2 mFc Chimera[Biotin], Avi, Human")
TGF-beta RII/TGFBR2 mFc Chimera[Biotin], Avi, Human
Artikelnummer: GSC-Z04620-100
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-beta) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects...
| Schlagworte: | TGFBR2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II |
| Ursprungsart: | human |
| MW: | 44 kD |
ab 887,00 €
TGF-beta RII/TGFBR2 hFc Chimera, Human
Artikelnummer: GSC-Z05873-100
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-beta) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects...
| Schlagworte: | TGFBR2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II |
| Ursprungsart: | human |
| MW: | 44.2 kD |
ab 497,00 €
TGF-beta RII/TGFBR2, mFc Chimera, Avi, Human
Artikelnummer: GSC-Z05872-100
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-beta) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects...
| Schlagworte: | TGFBR2, TGF-beta receptor type-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II |
| Ursprungsart: | human |
| MW: | 44 kD |
ab 457,00 €
LY2109761
Artikelnummer: Cay15409-1
LY2157299 is a small molecule inhibitor of the TGF-beta receptor type 1/type II kinases (IC50 = 69 nM). It has been used to study the role of TGF-beta signaling in tumor cell migration and metastasis in pancreatic tumor cell lines where 5 µM of the compound completely disrupts Smad-2 phosphorylation, an immediate...
| Schlagworte: | 4-[5,6-dihydro-2-(2-pyridinyl)-4H-pyrrolo[1,2-b]pyrazol-3-yl]-7-[2-(4-morpholinyl)ethoxy]-quinoline |
| Anwendung: | TGFBR1/2 inhibitor |
| CAS | 700874-71-1 |
| MW: | 441.5 D |
ab 67,00 €
Anti-TGFBR2 / TGF beta Receptor II
Artikelnummer: NSJ-R32086
0.5mg/ml if reconstituted with 0.2ml sterile DI water. TGFBR2 (Transforming growth factor, beta receptor II) is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein,...
| Schlagworte: | Anti-TGFBR2, Anti-TGFR-2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta type II receptor,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-Tgfbr2
Artikelnummer: NSJ-F45533-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators....
| Schlagworte: | Anti-Tgfbr2, Anti-TGFR-2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
ITD 1
Artikelnummer: Cay23326-10
ITD 1 is an inhibitor of TGF-beta (IC50 = 0.85 µM). It is selective for TGF-beta in an SBE4/Smad reporter assay, providing 83% inhibition when used at a concentration of 2.5 µM, over activin A, which is inhibited by 51% when used at the same concentration. ITD 1 inhibits TGF-beta signaling by induction of TGF-beta...
| Schlagworte: | 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid, ethyl ester |
| Anwendung: | TGF-beta inhibitor, TGF-beta receptor type II degradation inducer |
| CAS | 1099644-42-4 |
| MW: | 415.5 D |
ab 139,00 €
Anti-TGFBR2
Artikelnummer: A304-413A
Protein function: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus...
| Schlagworte: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-TGFBR2
Artikelnummer: A304-414A
Protein function: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus...
| Schlagworte: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
TGFbetaR2, human, recombinant, N-terminal GST-tag
Artikelnummer: BPS-40707
Human transforming growth factor beta receptor 2 (TGFbetaR2). GenBank Accession No. NM_003242 (var2), a.a. 190-567 (end), with N-terminal GST-tag, MW=69.9 kDa, expressed in an Sf9 cell expression system.
| Schlagworte: | TGFBR2, TGFR-2, TbetaR-II, EC=2.7.11.30, TGF-beta receptor type-2, TGF-beta type II receptor, TGF-beta receptor type II,... |
| Anwendung: | Studying protein binding, receptor activity, screening small molecules |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 69.9 kD |
625,00 €
Anti-TGFBR2
Artikelnummer: NSJ-R30965
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transforming growth factor, beta receptor II, also known as TGFBR2 and TGFR-2, is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. A TGFBR2 cDNA encoding a deduced 565-amino acid protein with a calculated molecular mass of...
| Schlagworte: | Anti-TGFBR2, Anti-TGFR-2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-TGFbeta RII
Artikelnummer: E-AB-33088.120
TGFBR2 (Transforming Growth Factor Beta Receptor 2) is a Protein Coding gene. Diseases associated with TGFBR2 include Loeys-Dietz Syndrome 2 and Esophageal Cancer. Among its related pathways are SMAD2/3 MH2 Domain Mutants in Cancer and Extracellular vesicle-mediated signaling in recipient cells. GO annotations...
| Schlagworte: | Anti-TGFR-2, Anti-TGFBR2, Anti-TbetaR-II, EC=2.7.11.30, Anti-TGF-beta receptor type-2, Anti-TGF-beta receptor type II,... |
| Anwendung: | WB, IHC (paraffin), ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €