COX-2 (human) Inhibitor Screening Assay Kit

COX-2 (human) Inhibitor Screening Assay Kit
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
Cay701080-96 96 wells -

5 - 10 Werktage*

469,00 €
 
COX-1 and COX-2 catalyze the production of the prostaglandin (PG) and thromboxane precursor PGH2.... mehr
Produktinformationen "COX-2 (human) Inhibitor Screening Assay Kit"
COX-1 and COX-2 catalyze the production of the prostaglandin (PG) and thromboxane precursor PGH2. COX-2 is primarily responsible for the biosynthesis of PGs under acute inflammatory conditions. The COX-2 (human recombinant) Inhibitor Screening Assay measures PGF2alpha that is produced by SnCl2 reduction of COX-2-derived PGH2. PGF2alpha is quantified via enzyme immunoassay (EIA) using a broadly specific antiserum that binds to all the major PG compounds. This assay includes human recombinant COX-2 and is an excellent tool which can be used for general inhibitor screening, or to eliminate false positive leads generated by less specific methods. Synonyms: Cyclooxygenase 2. Origin: Animal/Sheep.
Schlagworte: Cyclooxygenase 2
Hersteller: Cayman Chemical
Hersteller-Nr: 701080

Eigenschaften

Anwendung: Inhibitor screening
Immunogen: Prostaglandin E1 100%|Prostaglandin E2 100%|Prostaglandin F1alpha 100%|Prostaglandin F2alpha 100%|Prostaglandin F3alpha 51.3%|Prostaglandin E2 Ethanolamide 44.0%|6-keto Prostaglandin F1alpha 43.6%|8-iso Prostaglandin F2alpha 38.4%|8-iso Prostaglandin E2 28.5%|Prostaglandin D2 26.6%|8-iso-2,3-dinor Prostaglandin F1alpha 20.0%|Prostaglandin E3 9.5%|Thromboxane B2 5.0%|12(S)-HHTrE 0.25%|Leukotriene D4 0.2%|Arachidonic Acid <0.01%|Leukotriene B4 <0.01%|Leukotriene C4 <0.01%|Leukotriene E4 <0.01%|Misoprostol <0.01%|Misoprostol (free acid) <0.01%|Prostaglandin A1 <0.01%|Prostaglandin A2 <0.01%|Prostaglandin A3 <0.01%|Prostaglandin B1 <0.01%|15-keto Prostaglandin E2 <0.01%|13,14-dihydro-15-keto Prostaglandin F2alpha <0.01%
Format: Solid Phase

Handhabung & Sicherheit

Lagerung: -80°C
Versand: -20°C (International: -80°C)
Signalwort: Danger
GHS-Piktogramme:
H-Sätze: H225, H227, H301, H302, H311, H314, H315, H316, H317, H319, H331, H400
P-Sätze: P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P273, P280, P301+310, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P310, P311, P312, P321, P330, P332+313, P333+313, P337+313, P361+364, P362+364, P363, P370+378, P391, P403, P403+233, P403+235,
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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