Produkte von Indigo Biosciences
Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.
Mehr Informationen unter: www.indigobiosciences.com
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GR Bioassay for Environmental Sample Monitoring
Artikelnummer: IB-EM00201
This Glucocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to ER Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Dexamethasone, Luciferase...
| Schlagworte: | GR, GRL, NR3C1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
ER Bioassay for Environmental Sample Monitoring
Artikelnummer: IB-EM00431
This Estrogen Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to ER Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist 17beta-estradiol (E2),...
| Schlagworte: | ER, ESR, ESR1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
MR Bioassay for Environmental Sample Monitoring
Artikelnummer: IB-EM00501
This Mineralocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to MR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Aldosterone, Luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
AR Bioassay for Environmental Sample Monitoring
Artikelnummer: IB-EM03001
This Androgen Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to AR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, Luciferase Detection Reagent, and a cell culture-ready...
| Schlagworte: | AR, DHTR, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
AhR Bioassay for Environmental Sample Monitoring
Artikelnummer: IB-EM06001
This Aryl Hydrocarbon Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to AhR Reporter Cells, this kit includes are two optimized media for use during cell culture and in diluting the user's test samples, Luciferase Detection...
| Schlagworte: | AhR, bHLHe76, Ah receptor, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
GM-CSFR Reporter Assay System (Human)
Artikelnummer: IB-IB30001
This Granulocyte-Macrophage Colony-Stimulating Factor Receptor (GM-CSFR) assay kit is an all-inclusive luciferase reporter assay system that includes, in addition to GM-CSFR Reporter Cells, optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample...
| Schlagworte: | CD116, CSF2R, CDw116, CSF2RA, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, Granulocyte-macrophage colony-stimulating factor... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
GM-CSFR Reporter Assay System (Human)
Artikelnummer: IB-IB30002
This Granulocyte-Macrophage Colony-Stimulating Factor Receptor (GM-CSFR) assay kit is an all-inclusive luciferase reporter assay system that includes, in addition to GM-CSFR Reporter Cells, optimized culture medium for use in reviving the cryopreserved cells, a culture medium for use in preparing test sample...
| Schlagworte: | CD116, CSF2R, CDw116, CSF2RA, GMR-alpha, GMCSFR-alpha, GM-CSF-R-alpha, Granulocyte-macrophage colony-stimulating factor... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
MR Reporter Assay System (Mouse)
Artikelnummer: IB-M00501
This Mouse Mineralocorticoid Receptor (MR) assay kit is an all-inclusive mouse MR reporter assay system that includes, in addition to mouse MR Reporter Cells, two optimized media for use during cell culture and (optionally) in diluting the test samples, a reference agonist, Luciferase Detection Reagent, a cell...
| Schlagworte: | MR, Mlr, Nr3c2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
1.588,00 €
LXRb Reporter Assay System (dog)
Artikelnummer: IB-D00301
| Schlagworte: | Nuclear receptor subfamily 1 group H member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | dog |
1.588,00 €
LXRa Reporter Assay System (dog)
Artikelnummer: IB-D00311
| Schlagworte: | Nuclear receptor subfamily 1 group H member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | dog |
1.588,00 €
INSRb Reporter Assay System (human)
Artikelnummer: IB-IB28002
Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
| Schlagworte: | INSR, EC=2.7.10.1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
IGF-1R Reporter Assay System (human)
Artikelnummer: IB-IB29001
Protein function: Receptor tyrosine kinase which mediates actions of insulin- like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of...
| Schlagworte: | IGF1R, EC=2.7.10.1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €