Produkte von Indigo Biosciences
Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.
Mehr Informationen unter: www.indigobiosciences.com
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PPARalpha (rat) Reporter Assay Kit
Artikelnummer: IB-R00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the rat peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or rPPARalpha. INDIGO's reporter cells include...
| Schlagworte: | PPARA, NR1C1, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | rat |
ab 1.588,00 €
TRbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB01101
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human thyroid hormone receptor beta (NR1A2), a ligand-dependent transcription factor commonly referred to as TRbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | THRB, ERBA2, c-erbA-2, c-erbA-beta, Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
PPARalpha (mouse) Reporter Assay Kit
Artikelnummer: IB-M00111
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the mouse peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or mPPARalpha. INDIGO's reporter cells include...
| Schlagworte: | Ppara, Nr1c1, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
ab 1.588,00 €
PPARdelta (rat) Reporter Assay Kit
Artikelnummer: IB-R00121
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the rat peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or rPPARdelta. INDIGO's reporter cells include...
| Schlagworte: | Ppard, PPARb, Protein Ppard, Peroxisome proliferator-activated receptor beta, Peroxisome proliferator activated receptor... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | rat |
ab 1.588,00 €
PXR (Rat) Reporter Assay System
Artikelnummer: IB-R07001
Protein function: Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific...
| Schlagworte: | Pxr, Nr1i2, Pregnane X receptor, Orphan nuclear receptor PXR, Nuclear receptor subfamily 1 group I member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | rat |
ab 1.588,00 €
![FGFR/beta-Klotho Reporter Assay System [Human]](https://www.biomol.com/media/image/78/af/99/IB-IB22002_200x200.png "FGFR/beta-Klotho Reporter Assay System [Human]")
FGFR/beta-Klotho Reporter Assay System [Human]
Artikelnummer: IB-IB22002
The family of Fibroblast Growth Factors (FGFs) comprise approximately 23 members that are related by core sequence and structure conservation, with the majority of FGFs being secreted signaling proteins. Secreted FGFs are predominantly autocrine and paracrine factors, with only three members evolved to function as...
| Schlagworte: | Fibroblast Growth Factor Receptor 1c , FGFR1c/beta-Klotho, BKL, KLB, BetaKlotho, Beta-klotho, Klotho beta-like protein,... |
| Anwendung: | Functional activity screening, For endocrine FGF Signaling |
| Spezies-Reaktivität: | human |
4.175,00 €
INDIGlo Luciferase Detection Reagent Kit
Artikelnummer: IB-LDR-10
INDIGlo Luciferase Detection Reagent (LDR) is formulated to deliver steady, long-lived luminescence signal from mammalian reporter cells expressing firefly luciferase. For convenience, the reagent is provided 'ready to use', without the requirement to first re-constitute powder-form components. INDIGlo LDR works...
| Anwendung: | Steady, long-lived luminescence signal, Firefly luciferase reporter |
| Spezies-Reaktivität: | broad |
ab 206,00 €
Rat ERa Reporter Assay System
Artikelnummer: IB-R00401
This Rat Estrogen Receptor Alpha (rERalpha) assay kit is an all-inclusive firefly luciferase reporter assay system that includes in addition to rERalpha Reporter Cells, two optimized media for use during cell culture and (optionally) in diluting the test samples, a reference agonist, Luciferase Detection Reagent, a...
| Schlagworte: | ER, Esr, Esr1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | rat |
ab 1.588,00 €
Mouse AhR Reporter Assay System
Artikelnummer: IB-M06001
This Mouse Aryl Hydrocarbon Receptor (mAhR) assay kit is an all-inclusive firefly luciferase reporter assay system that includes in addition to mAhR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, a reference agonist (MeBIO), Luciferase Detection Reagent, and...
| Schlagworte: | Ahr, AhR, Ah receptor, Aryl hydrocarbon receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | mouse |
ab 1.588,00 €
![ERRb Reporter Assay System [Human]](https://www.biomol.com/media/image/7e/96/ce/IB-IB08011_200x200.png "ERRb Reporter Assay System [Human]")
ERRb Reporter Assay System [Human]
Artikelnummer: IB-IB08011
This Estrogen-related Receptor Beta (ERRbeta) assay kit is an all-inclusive firefly luciferase reporter assay system that includes, in addition to ERRbeta Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference inverse-agonist 4-Hydroxy Tamoxifen,...
| Schlagworte: | Human ERRb Reporter Assay System, ERRB2, RR-beta, ERR beta-2, Estrogen receptor-like 2, Steroid hormone receptor ERR2,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
![ERRb Reporter Assay System [Human]](https://www.biomol.com/media/image/71/19/46/IB-IB08012_200x200.png "ERRb Reporter Assay System [Human]")
ERRb Reporter Assay System [Human]
Artikelnummer: IB-IB08012
This Estrogen-related Receptor Beta (ERRbeta) assay kit is an all-inclusive firefly luciferase reporter assay system that includes, in addition to ERRbeta Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference inverse-agonist 4-Hydroxy Tamoxifen,...
| Schlagworte: | Human ERRb Reporter Assay System, ERRB2, RR-beta, ERR beta-2, Estrogen receptor-like 2, Steroid hormone receptor ERR2,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
![TPOR Reporter Assay System [Human]](https://www.biomol.com/media/image/04/85/f6/IB-IB20002_200x200.png "TPOR Reporter Assay System [Human]")
TPOR Reporter Assay System [Human]
Artikelnummer: IB-IB20002
This assay utilizes proprietary human cells that provide constitutive expression fo the Human Thrombopoietin Receptor (TPOR). TPOR, also known as MPL or CD110, is a member of the type I cytokine receptor superfamily. Thrombopoietin (TPO), the physiological activator of TPOR, is a glycoprotein that regulates...
| Schlagworte: | MPL, TPOR, CD110, TPO-R, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €