Produkte von Indigo Biosciences
Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.
Mehr Informationen unter: www.indigobiosciences.com
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ADRB2 Reporter Assay System (human)
Artikelnummer: IB-IB32101
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Beta 2 (ADRB2). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRB2. In addition to ADRB2 Reporter Cells, this kit provides...
| Schlagworte: | ADRB2, ADRB2R, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
PPARgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00102
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
| Schlagworte: | NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
PPARalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00112
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor alpha (NR1C1), a ligand-dependent transcription factor commonly referred to as PPARA or PPARalpha. INDIGO's reporter cells include...
| Schlagworte: | NR1C1, PPARA, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1, Peroxisome proliferator-activated receptor alpha |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
PPARdelta (human) Reporter Assay Kit
Artikelnummer: IB-IB00122
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor delta (NR1C2), a ligand-dependent transcription factor commonly referred to as PPARD or PPARdelta. INDIGO's reporter cells include...
| Schlagworte: | NUCI, NUC1, NR1C2, PPARD, PPAR-beta, PPAR-delta, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
LXR (human) Reporter Assays Panel
Artikelnummer: IB-IB00321-48P
INDIGO's panel of LXR Assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (NR1H3) and beta (NR1H2), ligand-dependent transcription factors commonly referred to as LXRalpha and LXRbeta. INDIGO's reporter cells include the luciferase reporter gene functionally linked to an...
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
2.176,00 €
ERbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00412
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the full-length human estrogen receptor 2 (NR3A2), a ligand-dependent transcription factor commonly referred to as ERbeta. INDIGO's reporter cells include the luciferase reporter gene...
| Schlagworte: | ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
ER (human) Reporter Assays Panel
Artikelnummer: IB-IB00421-48P
INDIGO's panel of ER assays utilizes non-human mammalian cells engineered to express human estrogen receptors alpha (ER1, NR3A1) and beta (ER2, NR3A2), ligand-dependent transcription factors commonly referred to as ERalpha and ERbeta. INDIGO's ER reporter cells include the luciferase reporter gene functionally...
| Schlagworte: | estrogen receptor alpha, ER1, NR3A1, estrogen receptor beta, ER2, NR3A2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
2.176,00 €
VDR (human) Reporter Assay Kit
Artikelnummer: IB-IB00702
This nuclear receptor assay system utilizes proprietary human cells engineered to provide constitutive, high-level expression of the human vitamin D receptor (NR1I1), a ligand-dependent transcription factor commonly referred to as VDR. INDIGO's reporter cells include the luciferase reporter gene functionally linked...
| Schlagworte: | VDR, NR1I1, Vitamin D3 receptor, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
RXRalpha (human) Reporter Assay Kit
Artikelnummer: IB-IB00802
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor alpha (NR2B1), a ligand-dependent transcription factor commonly referred to as RXRA or RXRalpha. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRA, NR2B1, Retinoid X receptor alpha, Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
RXRbeta (human) Reporter Assay Kit
Artikelnummer: IB-IB00812
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor beta (NR2B2), a ligand-dependent transcription factor commonly referred to as RXRB or RXRbeta. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRB, NR2B2, Retinoid X receptor beta, Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
RXRgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00822
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
RXR (human) Reporter Assays Panel
Artikelnummer: IB-IB00831-32P
INDIGO's panel of RXR reporter assays utilizes non-human mammalian cells engineered to individually express human retinoic acid receptors, RXRalpha (NR2B1), RXRbeta (NR2B2), or RXRgamma (NR2B3). INDIGO's RXR reporter cells include the luciferase reporter gene functionally linked to a responsive promoter. Thus,...
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
2.176,00 €