Produkte von Indigo Biosciences
Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.
Mehr Informationen unter: www.indigobiosciences.com
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Zebrafish ERa Reporter Assay System
Artikelnummer: IB-Z00401
The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
| Schlagworte: | ER, esr, esr1, ER-alpha, Estrogen receptor, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Zebrafish |
ab 1.588,00 €
Zebrafish TRb Reporter Assay System
Artikelnummer: IB-Z01101
The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
| Schlagworte: | TRb, thrb, nr1a2, TRbeta1, TR-beta, Thyroid hormone receptor beta, Thyroid hormone receptor beta-1, Nuclear receptor... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Zebrafish |
ab 1.588,00 €
Zebrafish RARalpha A Reporter Assay System
Artikelnummer: IB-Z02201
The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
| Schlagworte: | nr1b1a, zRAR alpha, RAR-alpha-A, RAR-alpha-2.A, Retinoic acid receptor alpha, Retinoic acid receptor alpha-A, Retinoic... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Zebrafish |
ab 1.588,00 €
Zebrafish AR Reporter Assay System
Artikelnummer: IB-Z03001
The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
| Schlagworte: | Androgen receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Zebrafish |
ab 1.588,00 €
Zebrafish AhR Reporter Assay System
Artikelnummer: IB-Z06001
The principle application of this assay product is in the screening of test samples to quantify functional activities, either agonist or antagonist. This kit product is an all-inclusive assay system that includes, in addition to Reporter Cells, two optimized media for use during cell culture and (optionally) in...
| Schlagworte: | Aryl hydrocarbon receptor 1B |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Zebrafish |
ab 1.588,00 €
Expression Profiling of Clinically Relevant CYPs...
Artikelnummer: IB-UGE1003-48
The reagents and materials provided in the assay kit for the Expression Profiling of Clinically Relevant CYPs are formatted to allow for two alternative cell culture setups. In one scenario 48 culture wells may be set up at two different times. In the other assay scenario 96 culture wells may be set up at one time....
| Spezies-Reaktivität: | human |
1.911,00 €
Drug-Induced Hepatotoxicity Assay Utiilizing upcyte...
Artikelnummer: IB-ULC1003-48
The principal application of this assay is to rapidly screen test compounds to identify those that induce acute liver cell toxicity. This kit includes two aliquots of cryopreserved Luminescent Reporter Hepatocytes (upcyte(R)), donor 10-13, isolated from an adult Caucasian female, that have been further modified to...
| Spezies-Reaktivität: | human |
1.617,00 €
Human TEAD4/YAP Assay System, 96-well format assays
Artikelnummer: IB-IB16001
Kits are offered in different assay formats to accommodate researchers' needs: 3x 32, 1x 96, and 1x 384 assay formats for screening small numbers of test compounds, as well as custom bulk reagents for HTS applications. Assay systems are all inclusive, providing reporter cells, optimized growth media, media for...
| Schlagworte: | RTEF1, TEAD4, TEAD-4, TEA domain family member 4, Transcription factor RTEF-1, Transcription factor 13-like 1,... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
Nuclear Factor of Activated T cells (NFAT)
Artikelnummer: IB-IB18001
This Nuclear Factor of Activated T cells (NFAT) kit product is an all-inclusive assay system that includes addition to NFAT Reporter Cells, two optimized media for use during cells culture and in diluting test samples, the calcineurin-NFAT pathway activator Ionomycin, Luciferase Detection Reagent, and a cell...
| Anwendung: | Functional activity screening |
ab 1.588,00 €
Nuclear Factor of Activated T cells (NFAT)
Artikelnummer: IB-IB18002
This Nuclear Factor of Activated T cells (NFAT) kit product is an all-inclusive assay system that includes addition to NFAT Reporter Cells, two optimized media for use during cells culture and in diluting test samples, the calcineurin-NFAT pathway activator Ionomycin, Luciferase Detection Reagent, and a cell...
| Anwendung: | Functional activity screening |
4.175,00 €
Cannabinoid Type 1 Receptor (CB1R) Reporter Assay System...
Artikelnummer: IB-IB19002
This assay uses proprietary human cells that provide constitutive expression of the Human Cannabinoid Type 1 Receptor, also referred to as CB1R. CB1R is one of the two main cannabinoid receptors identified as part of the endocannabinoid system. CB1R is highly expressed in the central nervous system, but also in...
| Schlagworte: | CB1, CNR, CB-R, CNR1, CANN6, Cannabinoid receptor 1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Human |
4.175,00 €
Fibroblast Growth Factor Receptors 1 & 2 for Paracrine...
Artikelnummer: IB-IB21002
The family of Fibroblast Growth Factors (FGFs) comprise approximately 23 members that are related by core sequence and structure conservation, with the majority of FGFs being secreted signaling proteins. Secreted FGFs are predominantly autocrine and paracrine factors, with only three members evolved to function as...
| Schlagworte: | CD331, FLT-2, FGFR1, BFGFR, N-sam, FGFR-1, bFGF-R-1, Proto-oncogene c-Fgr, Fms-like tyrosine kinase 2, Fibroblast growth... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | Human |
4.175,00 €