Produkte von Indigo Biosciences
Indigo Biosciences, Inc. wurde im Jahr 2005 in State College, Pennsylvania von Dr. Jack Vanden Heuvel und Dr. Blake Peterson gegründet. Das biowissenschaftliche Unternehmen konzentriert sich auf Produkte und Dienstleistungen im Bereich in vitro-Toxikologie und Kernrezeptoren. Diese Rezeptoren stellen eine wichtige Klasse von therapeutischen Wirkstoffzielen dar. Hierbei sind quantitative Aktivitätsassays noch immer eine besondere Herausforderung für die Biotechnologie. Die beiden Gründer des Unternehmens sind international anerkannte Spezialisten auf diesem Gebiet und nutzten ihre gesammelte Expertise in der Kernrezeptorbiologie, Toxikologie, medizinischer Chemie und Molekularbiologie, um die Technologie-Plattform für diese Produkte zu entwickeln.
Mehr Informationen unter: www.indigobiosciences.com
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ADRB3 Reporter Assay System (human)
Artikelnummer: IB-IB32202
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Beta 3 (ADRB3). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRB3. In addition to ADRB1 Reporter Cells, this kit provides...
| Schlagworte: | ADRB3, Beta-3 adrenoreceptor, Beta-3 adrenergic receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
GLP-1R Inhibition Reporter Assay System (human)
Artikelnummer: IB-IB33101
Protein Function: G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449, PubMed:7517895, PubMed:8216285, PubMed:8405712). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and...
| Schlagworte: | GLP1R, Glucagon-like peptide 1 receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
ADRA2A Reporter Assay System (human)
Artikelnummer: IB-IB34002
This is an all-inclusive cell-based luciferase reporter assay kit targeting the Human Adrenoceptor Alpha 2A (ADRA2A). INDIGO's ADRA2A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA2A. In addition to ADRA2A Reporter Cells, this kit provides...
| Schlagworte: | ADRA2A, Alpha-2A adrenoreceptor, Alpha-2A adrenergic receptor, Alpha-2 adrenergic receptor subtype C10 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
AVPR2 Reporter Assay System (human)
Artikelnummer: IB-IB37202
This is an all-inclusive cell-based luciferase reporter assay kit targeting the Human Arginine Vasopressin Receptor 2 (AVPR2). INDIGO's AVPR1B reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the AVPR2. In addition to AVPR2 Reporter Cells, this kit...
| Schlagworte: | AVPR2, AVPR V2, Vasopressin V2 receptor, Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
CHRM1 Activation Reporter Assay System (human)
Artikelnummer: IB-IB44001
This is an all-inclusive cell-based luciferase reporter assay kit for the activation of Human Cholinergic Receptor, Muscarinic 1 (CHRM1). INDIGO's CHRM1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the CHRM1. In addition to CHRM1 Reporter Cells,...
| Schlagworte: | CHRM1, Muscarinic acetylcholine receptor M1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
CHRM1 Inhibition Reporter Assay System (human)
Artikelnummer: IB-IB44101
This is an all-inclusive cell-based luciferase reporter assay kit for the inhibition of Human Cholinergic Receptor, Muscarinic 1 (CHRM1). INDIGO's CHRM1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the CHRM1. In addition to CHRM1 Reporter Cells,...
| Schlagworte: | CHRM1, Muscarinic acetylcholine receptor M1 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
GCGR Reporter Assay System (human)
Artikelnummer: IB-IB45002
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Glucagon Receptor (GCGR). INDIGO's GCGR reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the GCGR. In addition to GCGR Reporter Cells, this kit provides two...
| Schlagworte: | GCGR, Glucagon receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
PrRPR Reporter Assay System (human)
Artikelnummer: IB-IB49001
This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Prolactin-Releasing Peptide Receptor (PrRPR / GPR10). INDIGO's PrRPR reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the PrRPR. In addition to PrRPR Reporter...
| Schlagworte: | hGR3, PRLHR, G-protein coupled receptor 10, Prolactin-releasing peptide receptor |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
TPOR Reporter Assay System [Human]
Artikelnummer: IB-IB20001
This assay utilizes proprietary human cells that provide constitutive expression fo the Human Thrombopoietin Receptor (TPOR). TPOR, also known as MPL or CD110, is a member of the type I cytokine receptor superfamily. Thrombopoietin (TPO), the physiological activator of TPOR, is a glycoprotein that regulates...
| Schlagworte: | MPL, TPOR, CD110, TPO-R, Proto-oncogene c-Mpl, Thrombopoietin receptor, Myeloproliferative leukemia protein |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
FGFR/beta-Klotho Reporter Assay System [Human]
Artikelnummer: IB-IB22001
The family of Fibroblast Growth Factors (FGFs) comprise approximately 23 members that are related by core sequence and structure conservation, with the majority of FGFs being secreted signaling proteins. Secreted FGFs are predominantly autocrine and paracrine factors, with only three members evolved to function as...
| Schlagworte: | Fibroblast Growth Factor Receptor 1c , FGFR1c/beta-Klotho, BKL, KLB, BetaKlotho, Beta-klotho, Klotho beta-like protein,... |
| Anwendung: | Functional activity screening, for endocrine FGF Signaling |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
AVPR1B Reporter Assay System (human)
Artikelnummer: IB-IB37101
This is an all-inclusive cell-based luciferase reporter assay kit targeting the Human Arginine Vasopressin Receptor 1B (AVPR1B). INDIGO's AVPR1B reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the AVPR1B. In addition to AVPR1B Reporter Cells, this...
| Schlagworte: | V1bR, AVPR3, AVPR1B, AVPR V3, AVPR V1b, Vasopressin V3 receptor, Vasopressin V1b receptor, Antidiuretic hormone receptor 1b |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.588,00 €
AVPR1B Reporter Assay System (human)
Artikelnummer: IB-IB37102
This is an all-inclusive cell-based luciferase reporter assay kit targeting the Human Arginine Vasopressin Receptor 1B (AVPR1B). INDIGO's AVPR1B reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the AVPR1B. In addition to AVPR1B Reporter Cells, this...
| Schlagworte: | V1bR, AVPR3, AVPR1B, AVPR V3, AVPR V1b, Vasopressin V3 receptor, Vasopressin V1b receptor, Antidiuretic hormone receptor 1b |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €