Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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CD40L (human) (multimeric) (rec.)
Artikelnummer: AG-40B-0010-C010
Human CD40L (amino acids 116-261) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-111) and a FLAG(R)-tag. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86) (ED50: <1ng/ml). Lyophilized. Contains PBS. MultimericCD40L is a high activity construct in which two...
| Schlagworte: | MegaCD40L(TM), Soluble (human, rec.), ACRP30headless:CD40L, ACRP30headless:CD154, ACRP30headless:TNFSF5, ADIPOQ-CD40L |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
ab 374,00 €
Trolox
Artikelnummer: AG-CR1-3639-M500
White to off-white or pale yellow solid. Soluble in DMSO (20mg/ml), 100% ethanol (20mg/ml) or methanol (5mg/ml). Slightly soluble in water (~1mg/ml) and PBS (3mg/ml). Cell permeable and water soluble derivative of vitamin E, Potent antioxidant. Efficiently prevents formation of different reactive oxygen species,...
| Schlagworte: | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, Trolox C |
| Anwendung: | Potent antioxidant |
| CAS | 53188-07-1 |
| MW: | 250,3 D |
ab 44,00 €
Actinomycin D
Artikelnummer: BVT-0089-M005
Antibiotic, Antitumor compound, Cytotoxic, Apoptosis inducer, RNA synthesis inhibitor, DNA intercalating agent, Mcl-1 expression inhibitor, p53 pathway activator. Isolated from Streptomyces parvulus.
| Schlagworte: | Actinomycin IV, Actinomycin C1, Dactinomycin |
| Anwendung: | p53 pathway activator |
| CAS | 50-76-0 |
| MW: | 1255,4 D |
ab 55,00 €
Ganglioside GQ1b . tetrasodium salt (bovine brain)
Artikelnummer: AG-CN2-9007-C500
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GQ1b . 4Na, Tetrasialoganglioside GQ1b . 4Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 68652-37-9 |
| MW: | 2416,6 D |
ab 193,00 €
Daptomycin
Artikelnummer: AG-CN2-0542-M100
Isolated from Streptomyces sp. Appearance: Off-white to pale yellow powder. Solubility: Soluble in water (25mg/ml), DMSO (50mg/ml) or methanol (5mg/ml). Identity: Determined by 1H-NMR. InChi Key: DOAKLVKFURWEDJ-RWDRXURGSA-N Smiles:...
| Schlagworte: | LY146032, Dapcin, Cubicin, Cidecin |
| Anwendung: | Cyclic lipopeptide, Calcium-dependent antibiotic, Antibacterial, Cell membrane function inhibitor |
| CAS | 103060-53-3 |
| MW: | 1620.7 D |
ab 66,00 €
Anti-Jagged-1 (human), clone J1G53-3, FITC conjugated
Artikelnummer: AG-20A-0049F-C050
Recognizes human Jagged-1. Detects a band of about 180kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is...
| Schlagworte: | Protein Jagged-1, CD339, JAG1 |
| Anwendung: | FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
297,00 €
![PS-341 [Bortezomib]](https://www.biomol.com/media/image/e7/b4/85/AG-CR1-3602-M005_200x200.png "PS-341 [Bortezomib]")
PS-341 [Bortezomib]
Artikelnummer: AG-CR1-3602-M005
White solid. Soluble in DMSO, ethanol or methanol. Slightly soluble in water. Highly potent, selective and reversible cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome, Calpain and cathepsin inhibitor, Autophagy activator, Anticancer...
| Schlagworte: | PS-341, LDP-341, MLM-341, MG-341, NSC-681239, Proteasome Inhibitor |
| Anwendung: | Highly potent selective, reversible, cell permeable proteasome inhibitor |
| CAS | 179324-69-7 |
| MW: | 384,2 D |
ab 55,00 €
Ganglioside GD1a . disodium salt (bovine brain)
Artikelnummer: AG-CN2-9003-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GD1a . 2Na, Disialoganglioside GD1a . 2Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 12707-58-3 |
| MW: | 1836,1 D |
ab 110,00 €
Anti-TRAIL-R2 (human), clone TR2.21
Artikelnummer: AG-20B-0028-C100
Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex...
| Schlagworte: | TRAIL Receptor 2, DR5, KILLER, TNFRSF 10B, CD262 |
| Anwendung: | FC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
396,00 €
Anti-IDO (human)
Artikelnummer: AG-25A-0029-C100
Recognizes human IDO. Detects a band of about 45kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and...
| Schlagworte: | Indoleamine 2,3-dioxygenase, INDO |
| Anwendung: | ELISA, FC, ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
347,00 €
Kdo2-Lipid A (ready-to-use)
Artikelnummer: AG-CU1-0001-M001
Defined substructure of the Re mutant of lipopolysaccharide (LPS), Endotoxin activity equal to Re LPS, Strong activator (<10ng/ml) of macrophages via toll-like receptor 4 (TLR4), Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice by IL-6 ELISA, Facilitates...
| Schlagworte: | (3-Deoxy-D-manno-octulosonic acid)2-Lipid A, TLR4, CD284, hToll, Toll-like receptor 4 activation |
| Anwendung: | TLR4 activator |
| MW: | 2326,7 D |
143,00 €
Rosiglitazone
Artikelnummer: AG-CR1-3570-M010
Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and...
| Schlagworte: | BRL 49653, HSDB 7555, TDZ 01 |
| Anwendung: | PPAR-gamma agonist |
| Wirt: | Synthetic |
| CAS | 122320-73-4 |
| MW: | 357,4 D |
ab 33,00 €