Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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G418, sulfate
Artikelnummer: AG-CN2-0030-G005
Isolated from Micromonospora rhodorangea. Antibiotic. Cytotoxic to prokaryotic and eukaryotic cells by inhibiting the protein synthesis. Apoptosis inducer. Widely employed in the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II. Antiviral. Assay:...
| Schlagworte: | Geneticin, Antibiotic G418, BRN 1669188 |
| Anwendung: | Apoptosis inducer |
| CAS | 108321-42-2 |
ab 36,00 €
MTSSL
Artikelnummer: AG-CR1-3573-M050
Highly reactive, thiol-specific spin-label. Specific conformational probe of thiol site structure by its minimal rotational freedom and distance from the covalent disulfide linkage to the macromolecule under study. Used to label cysteine residues in proteins (site-directed labeling, SDS-labeling). Allows protein...
| Schlagworte: | Mts-SL, MTSL, (1-Oxyl-2,2,5,5-tetramethylpyrroline-3- methyl)methanethiosulfonate, Otmpmms |
| Anwendung: | Protein labeling, Thiol-specific spin-label |
| Wirt: | Synthetic |
| CAS | 81213-52-7 |
| MW: | 264,3 D |
ab 88,00 €
JC-1
Artikelnummer: AG-CR1-3568-M001
5 x 1 mg. The membrane-permeant dual-emission potential-sensitive JC-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-1 dye can be used as an indicator of mitochondrial membrane potential in a variety...
| Schlagworte: | 5,5',6,6'-Tetrachloro-1,1',3,3'-tetraethylbenzimidazolylcarbocyanine iodide |
| Anwendung: | Mitochondrial membrane potential indicator, FC |
| CAS | 3520-43-2 |
| MW: | 652,2 D |
ab 66,00 €
Semaglutide
Artikelnummer: AG-CP3-0040-M025
Synthetic. Soluble in aqueous solution (5% AcOH) (1mg/ml). Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner. Longer-acting alternative to liraglutide. Chemically similar to...
| Schlagworte: | Semaglutide (free acid), NN 9535, NNC 0113-0217, Ozempic,... |
| Anwendung: | Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist |
| CAS | 910463-68-2 |
| MW: | 4113.6 D |
ab 33,00 €
Anti-acetyl-alpha-Tubulin, clone TEU318
Artikelnummer: AG-20B-0068-C100
Detects K40 acetylation of alpha-tubulin, signal specifically increased by modification with tubulin acetyl transferase alpha-TAT1. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule...
| Schlagworte: | Anti-acetyl-Tubulin alpha chain, (acetylated Lys40, K40) |
| Anwendung: | WB, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | broad |
374,00 €
Antibiotic PF 1052
Artikelnummer: BVT-0338-M001
Antibiotic, Antibacterial, antifungal and phytotoxic. Isolated from Phoma sp.
| Schlagworte: | (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methyle... |
| Anwendung: | Bioassays |
| CAS | 147317-15-5 |
| MW: | 429,6 D |
ab 125,00 €
ONX 0914
Artikelnummer: AG-CR1-3674-M005
Synthetic. Chemical. CAS: 960374-59-8. Formula: C31H40N4O7. MW: 580.7. Synthetic. Potent and selective 20S immunoproteasome inhibitor. Targets the beta5i subunit [LMP7] of the 20S immunoproteasome (IC50=73nM) and with minimal crossreactivity to the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome...
| Schlagworte: | N-[2-(4-Morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]-L-tyrosina... |
| Anwendung: | Potent, selective 20S immunoproteasome (PSMB8) inhibitor |
| CAS | 960374-59-8 |
| MW: | 580,7 D |
ab 66,00 €
Artemisinin
Artikelnummer: AG-CN2-0467-M500
White solid. Soluble in DMSO or ethanol. Anti-malaria, Apoptosis inducer, Anti-cancer, Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO).
| Schlagworte: | Qinghaosu, Arteannuin |
| Anwendung: | Antimalaria, Apoptosis inducer, Anticancer |
| CAS | 63968-64-9 |
| MW: | 282,3 D |
ab 39,00 €
Ruxolitinib
Artikelnummer: AG-CR1-3624-M100
White to off-white solid. Soluble in DMSO or ethanol. Insoluble in water. Antineoplastic, anti-inflammatory and immunomodulating agent, Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50 = 322nM), Affects DC...
| Schlagworte: | INCB018424, INC 424 |
| Anwendung: | JAK1 inhibitor, JAK2 inhibitor |
| CAS | 941678-49-5 |
| MW: | 306,4 D |
ab 72,00 €
Papaverine . hydrochloride
Artikelnummer: AG-CN2-0414-G001
White to off-white crystalline powder. Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water. Smooth muscle relaxant and vasodilator, Phosphodiesterase PDE10A inhibitor, Antiviral, Antipsychotic.
| Schlagworte: | 6,7-Dimethoxy-1-veratrylisoquinoline, NSC 35443, NCI-C56359 |
| Anwendung: | Phosphodiesterase PDE10A inhibitor |
| CAS | 61-25-6 |
| MW: | 375,9 D |
ab 24,00 €
(S)-Roscovitine
Artikelnummer: AG-MR-C0002-M005
Soluble in DMSO, ethanol or methanol. Stock solutions can be made up to 10 mM in DMSO. (S)-enantiomer of (R)-roscovitine (Prod. No. MR-C0001). Potent selective cyclin-dependent kinase 1 (CDK1) inhibitor. Potential neuroprotectant for stroke. Crosses the blood brain barrier. Inhibits CDK5, consequently blocking...
| Schlagworte: | 6-Benzylamino-2-(S)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine |
| Anwendung: | CDK1 inhibitor |
| CAS | 186692-45-5 |
| MW: | 354,5 D |
ab 88,00 €
GE2270A
Artikelnummer: AG-CN2-0303-M001
Isolated from Planobispora rosea. White to off-white powder. Soluble in DMSO or other organic solvents. Thiopeptide antibiotic. Antibacterial agent by inhibiting bacterial protein synthesis. Active against numerous Gram-positive pathogens, including methicillin-resistant strains of Staphylococcus aureus and...
| Schlagworte: | Antibiotic GE 2270A, MDL 62879 |
| Anwendung: | Thiopeptide antibiotic, EF-Tu inhibitor |
| CAS | 134861-34-0 |
| MW: | 1290.5 D |
ab 105,00 €