Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Rapamycin
Artikelnummer: AG-CN2-0025-M001
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Schlagworte: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Anwendung: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
ab 28,00 €
YM-254890
Artikelnummer: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Schlagworte: | QS 3666A |
| Anwendung: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
ab 220,00 €
Forskolin
Artikelnummer: AG-CN2-0089-M025
Isolated from Coleus forskohlii. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor....
| Schlagworte: | Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489 |
| Anwendung: | Cell permeable adenylate cyclase activator |
| CAS | 66575-29-9 |
| MW: | 410,5 D |
ab 22,00 €
Empagliflozin
Artikelnummer: AG-CR1-3619-M010
White solid. Soluble in DMSO. Slightly soluble in water or ethanol. Antidiabetic agent, Potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor. >,300-fold selectivity over SGLT-1, 4, 5 and 6, SGLT-2 is found almost exclusively in the proximal tubules of nephronic components in kidneys. Inhibition...
| Schlagworte: | Jardiance, BI-10773 |
| Anwendung: | Antidiabetic agent, SGLT2 inhibitor |
| CAS | 864070-44-0 |
| MW: | 450,9 D |
ab 77,00 €
Periostin (human) ELISA Kit
Artikelnummer: AG-45B-0004-KI01
Protein function: Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX By similarity. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. [The UniProt...
| Schlagworte: | PN, OSF2, POSTN, OSF-2, Periostin, Osteoblast-specific factor 2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
627,00 €
FasL (human) (multimeric) (rec.)
Artikelnummer: AG-40B-0130-C010
Human FasL (aa 139-281) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG(R)-tag. Lyophilized. Contains PBS. MultimericFasL (human) is a high activity construct in which two trimeric FasL are artificially linked via the collagen domain of ACRP30. This construct very effectively simulates the...
| Schlagworte: | MegaFasL, Soluble (human) (rec.), SPA, APL, FasL, APTL, CD178, FASLG, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95... |
| Anwendung: | FasL aggregation stimulator |
| Exprimiert in: | Human cells |
| Ursprungsart: | human, mouse |
| MW: | 40 kD |
ab 363,00 €
Staurosporine
Artikelnummer: AG-CN2-0022-M001
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein...
| Schlagworte: | Antibiotic AM2282, Antibiotic 230, CCRIS 3272 |
| Anwendung: | Protein kinase inhibitor, Apoptosis inducer |
| CAS | 62996-74-1 |
| MW: | 466,5 D |
ab 33,00 €
G418, sulfate
Artikelnummer: AG-CN2-0030-G005
Isolated from Micromonospora rhodorangea. Antibiotic. Cytotoxic to prokaryotic and eukaryotic cells by inhibiting the protein synthesis. Apoptosis inducer. Widely employed in the selection of eukaryotic expression vectors, in combination with either aminoglycoside phosphotransferase 3' or APH II. Antiviral. Assay:...
| Schlagworte: | Geneticin, Antibiotic G418, BRN 1669188 |
| Anwendung: | Apoptosis inducer |
| CAS | 108321-42-2 |
ab 36,00 €
Semaglutide
Artikelnummer: AG-CP3-0040-M025
Synthetic. Soluble in aqueous solution (5% AcOH) (1mg/ml). Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner. Longer-acting alternative to liraglutide. Chemically similar to...
| Schlagworte: | Semaglutide (free acid), NN 9535, NNC 0113-0217, Ozempic,... |
| Anwendung: | Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist |
| CAS | 910463-68-2 |
| MW: | 4113.6 D |
ab 33,00 €
Anti-LAG-3 (human), clone 17B4), ATTO 647N conjugated
Artikelnummer: AG-20B-0012TS-T100
Recognizes human LAG-3. Liquid. In PBS containing 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function, and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely...
| Schlagworte: | Lymphocyte Activation Gene-3, FDC Protein, CD223 |
| Anwendung: | FC, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
462,00 €
Ganglioside GD1b . disodium salt (bovine brain)
Artikelnummer: AG-CN2-9004-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GD1b . 2Na, Disialoganglioside GD1b . 2Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 19553-76-5 |
| MW: | 1836,1 D |
193,00 €
Resveratrol
Artikelnummer: AG-CN2-0033-M050
Isolated from Polygonum cuspidatum. Its effects are numerous and include anti-cancer, anti-inflammatory, anti-fungal and has other beneficial cardiovascular effects.
| Schlagworte: | trans-3,4',5-Trihydroxystilbene, trans-Resveratrol, (E)-Resveratrol, 3,4',5-Stilbenetriol |
| Anwendung: | Antioxidant, Adipogenesis inhibitor, Chemopreventive |
| CAS | 501-36-0 |
| MW: | 228,2 D |
ab 33,00 €