Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Rapamycin
Artikelnummer: AG-CN2-0025-M001
Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
| Schlagworte: | Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024 |
| Anwendung: | mTOR inhibitor, Immunsuppressant, Apoptosis inducer |
| CAS | 53123-88-9 |
| MW: | 914,2 D |
ab 28,00 €
Caspase-1 (mouse) ELISA Kit
Artikelnummer: AG-45B-0002-KI01
Detection Type: Colorimetric. Assay Type: Sandwich 96 well assay. Sample Type: Cell Culture Supernatant. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 33pg/ml. Detects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1. Caspase-1 is the best-described inflammatory caspase. It...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
660,00 €
Ganglioside GM1 . sodium salt (bovine brain)
Artikelnummer: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
ab 110,00 €
YM-254890
Artikelnummer: AG-CN2-0509-MC05
Off-white solid. Soluble in DMSO (10mg/ml). Cyclic depsipeptide composed of unique amino acids differing from normal amino acids, Membrane permeable, potent and selective Galphaq family inhibitor, Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095&mu,M) by blocking the exchange of GDP for...
| Schlagworte: | QS 3666A |
| Anwendung: | G alpha q family inhibitor |
| CAS | 568580-02-9 |
| MW: | 960,1 D |
ab 220,00 €
Empagliflozin
Artikelnummer: AG-CR1-3619-M010
White solid. Soluble in DMSO. Slightly soluble in water or ethanol. Antidiabetic agent, Potent and selective sodium glucose co-transporter 2 (SGLT-2) inhibitor. >,300-fold selectivity over SGLT-1, 4, 5 and 6, SGLT-2 is found almost exclusively in the proximal tubules of nephronic components in kidneys. Inhibition...
| Schlagworte: | Jardiance, BI-10773 |
| Anwendung: | Antidiabetic agent, SGLT2 inhibitor |
| CAS | 864070-44-0 |
| MW: | 450,9 D |
ab 77,00 €
Asprosin (human) ELISA Kit
Artikelnummer: AG-45B-0010-KI01
Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein Fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to...
| Schlagworte: | FBN |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
605,00 €
Gasdermin D (mouse) ELISA Kit
Artikelnummer: AG-45B-0011-KI01
Detects full-length and cleaved mouse Gasdermin D (C-terminus) in cell culture supernatants and cell extracts. Does not cross-react with human gasdermin D. Sensitivity: 14pg/ml. Range: 15.6 to 1000pg/ml. Protein function: Gasdermin-D, N-terminal: Promotes pyroptosis in response to microbial infection and danger...
| Schlagworte: | Gsdmd, Gsdmdc1, Gasdermin Domain-containing Protein 1, Gasdermin-D (C-terminal), GSDMD-CT |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
660,00 €
Staurosporine
Artikelnummer: AG-CN2-0022-M001
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. Inhibits protein...
| Schlagworte: | Antibiotic AM2282, Antibiotic 230, CCRIS 3272 |
| Anwendung: | Protein kinase inhibitor, Apoptosis inducer |
| CAS | 62996-74-1 |
| MW: | 466,5 D |
ab 33,00 €
FGL1 (human) ELISA Kit
Artikelnummer: AG-45B-0022-KI01
ELISA Kit. Assay Type: Sandwich. Detection Type: Colorimetric. Sample Type: Cell Culture Supernatant,Plasma,Serum. Range: 7.8 to 500pg/ml. Sensitivity: 1.8pg/ml. FGL1 (Fibrinogen-like protein 1, also called Hepatocyte-derived fibrinogen-related protein 1, HFREP-1 or Hepassocin) was initially identified as an...
| Schlagworte: | Fibrinogen-like Protein 1, FGL-1, Hepatocyte-derived Fibrinogen-related Protein 1, HFREP-1, Hepassocin |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
660,00 €
Nampt (Visfatin/PBEF) (human) ELISA Kit
Artikelnummer: AG-45A-0006YEK-KI01
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form...
| Schlagworte: | PBEF, NAMPT, Nampt, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 693,00 €
IL-36alpha (human) ELISA Kit
Artikelnummer: AG-45B-0013-KI01
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) are members of the IL-1 cytokine family that bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. IL-36alpha, beta and gamma cytokines, similarly to IL-1beta, need to be processed to...
| Schlagworte: | FIL1E, IL-1F6, IL-1 epsilon, FIL1 epsilon, Interleukin-36 alpha, Interleukin-1 epsilon, Interleukin-1 family member 6 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
660,00 €
Acyl-CoA-binding Protein (human) ELISA Kit
Artikelnummer: AG-45B-0019-KI01
Colorimetric Sandwich ELISA Assay. Detects human ACBP in serum, plasma and cell culture supernatant. Range: 0.03125 to 2ng/ml. Sensitivity: 26pg/ml. Acyl-coenzyme A (CoA)-binding protein (ACBP) is an ubiquitously expressed 86 aa polypeptide that binds medium- and long-chain acyl-CoA esters with very high affinity....
| Schlagworte: | ACBP, Diazepam-binding Inhibitor, DBI, Endozepine, EP |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
660,00 €