Produkte von AdipoGen Life Sciences

AdipoGen

AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.

Mehr Informationen unter: www.adipogen.com

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Anti-Polyglutamate chain [Poly-E]
Anti-Polyglutamate chain [Poly-E]

Artikelnummer: AG-25B-0030-C050

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
Schlagworte: Anti-Poly-E, pAb (IN105), Anti-Poly-Glu
Anwendung: WB, ICC
Wirt: Rabbit
Spezies-Reaktivität: broad
440,00 €
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Anti-FLIP, clone Dave-2
Anti-FLIP, clone Dave-2

Artikelnummer: AG-20B-0005-C100

Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian...
Schlagworte: I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1
Anwendung: IP, WB
Wirt: Rat
Spezies-Reaktivität: human , mouse
462,00 €
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Nigericin, sodium salt
Nigericin, sodium salt

Artikelnummer: AG-CN2-0020-M005

Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
Schlagworte: Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464
Anwendung: Ionophore
CAS 28643-80-3
ab 72,00 €
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Anti-CD40 (mouse), clone FGK45) (preservative free)
Anti-CD40 (mouse), clone FGK45) (preservative free)

Artikelnummer: AG-20B-0036PF-C500

Recognizes mouse CD40. Liquid. In PBS. CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The interaction of CD40-CD40L is...
Schlagworte: Tumor Necrosis Factor Receptor Superfamily Member 5, CD40L Receptor
Anwendung: FC, Bioassays
Wirt: Rat
Spezies-Reaktivität: mouse
ab 149,00 €
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SB203580
SB203580

Artikelnummer: AG-CR1-0030-M001

Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferative, PDK1 inhibitor, Anti-inflammatory, Review.
Schlagworte: 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole
Anwendung: p38 MAP kinase inhibitor
CAS 152121-47-6
MW: 377,4 D
ab 39,00 €
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Paclitaxel
Paclitaxel

Artikelnummer: AG-CN2-0045-M005

Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
Schlagworte: Taxol, BMS 181339-01, NSC 125973
Anwendung: Apoptosis Inducer
Wirt: Taxus brevifolia
CAS 33069-62-4
MW: 853,9 D
ab 22,00 €
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Periostin (human) ELISA Kit
Periostin (human) ELISA Kit

Artikelnummer: AG-45B-0004-KI01

Protein function: Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX By similarity. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization. [The UniProt...
Schlagworte: PN, OSF2, POSTN, OSF-2, Periostin, Osteoblast-specific factor 2
Anwendung: ELISA
Spezies-Reaktivität: human
627,00 €
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Thapsigargin (high purity)
Thapsigargin (high purity)

Artikelnummer: AG-CN2-0003-M001

Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
Anwendung: SERCA inhibitor, Ca2+ releaser
CAS 67526-95-8
MW: 650,8 D
ab 55,00 €
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Progranulin (human) (rec.) (untagged)
Progranulin (human) (rec.) (untagged)

Artikelnummer: AG-40A-0188Y-C050

Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
Schlagworte: GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor
Anwendung: Cell culture
Exprimiert in: Human cells
Ursprungsart: human
MW: 74 kD
ab 220,00 €
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Latrunculin B
Latrunculin B

Artikelnummer: AG-CN2-0031-M001

Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
Schlagworte: LAT-B, NSC 339663
Anwendung: Actin polymerization inhibitor
CAS 76343-94-7
MW: 395,5 D
ab 154,00 €
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Y-27632 . dihydrochloride
Y-27632 . dihydrochloride

Artikelnummer: AG-CR1-3564-M010

Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stellate cell growth inhibition. Antinociceptive. Blocks...
Schlagworte: Y-27632 - 2HCL, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
Anwendung: ROCK kinase inhibitor
CAS 129830-38-2
MW: 320.2 D
ab 55,00 €
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Anti-Caspase-1 (p10) (mouse), clone Casper-2
Anti-Caspase-1 (p10) (mouse), clone Casper-2

Artikelnummer: AG-20B-0044-C100

Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4...
Schlagworte: Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE
Anwendung: WB
Wirt: Mouse
Spezies-Reaktivität: mouse
462,00 €
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