Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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MG-132
Artikelnummer: AG-CP3-0011-M005
Soluble in DMSO or ethanol. Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kappaB activation inhibitor through IkappaB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin...
| Schlagworte: | Z-Leu-Leu-Leu-CHO, Z-LLL-CHO, Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, MG132 |
| Anwendung: | Proteasome inhibitor |
| CAS | 133407-82-6 |
| MW: | 476 D |
ab 22,00 €
Anti-FLIP, clone Dave-2
Artikelnummer: AG-20B-0005-C100
Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian...
| Schlagworte: | I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1 |
| Anwendung: | IP, WB |
| Wirt: | Rat |
| Spezies-Reaktivität: | human , mouse |
462,00 €
Nigericin, sodium salt
Artikelnummer: AG-CN2-0020-M005
Isolated from Streptomyces hygroscopicus. Antibiotic. High affinity ionophore for monovalent cations such as H, K, Na, Pb2. Shows antibacterial (Gram-positive), antifungal, antitumor and antiviral activity. Disrupts membrane potential and Golgi apparatus in mitochondria. NLRP3/NALP3 activator. Signals through...
| Schlagworte: | Antibiotic K 178, Helexin C, Polyetherin A, BRN 1696755, Azalomycin M, Antibiotic X-464 |
| Anwendung: | Ionophore |
| CAS | 28643-80-3 |
ab 72,00 €
Anti-CD40 (mouse), clone FGK45) (preservative free)
Artikelnummer: AG-20B-0036PF-C500
Recognizes mouse CD40. Liquid. In PBS. CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The interaction of CD40-CD40L is...
| Schlagworte: | Tumor Necrosis Factor Receptor Superfamily Member 5, CD40L Receptor |
| Anwendung: | FC, Bioassays |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
ab 149,00 €
SB203580
Artikelnummer: AG-CR1-0030-M001
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferative, PDK1 inhibitor, Anti-inflammatory, Review.
| Schlagworte: | 4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole |
| Anwendung: | p38 MAP kinase inhibitor |
| CAS | 152121-47-6 |
| MW: | 377,4 D |
ab 39,00 €
Paclitaxel
Artikelnummer: AG-CN2-0045-M005
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Schlagworte: | Taxol, BMS 181339-01, NSC 125973 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
ab 22,00 €
Thapsigargin (high purity)
Artikelnummer: AG-CN2-0003-M001
Colorless to white amorphous powder. Soluble in DMSO or 100% ethanol. Chemical. CAS: 67526-95-8. Formula: C34H50O12. MW: 650.8. Isolated from Thapsia garganica. Intracellular Ca2+ signaling probe. Specific and sensitive inhibitor of SERCA. Non-TPA/PMA tumor promoter. Histamine release inducer. Apoptosis inducer....
| Anwendung: | SERCA inhibitor, Ca2+ releaser |
| CAS | 67526-95-8 |
| MW: | 650,8 D |
ab 55,00 €
Y-27632 . dihydrochloride
Artikelnummer: AG-CR1-3564-M010
Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stellate cell growth inhibition. Antinociceptive. Blocks...
| Schlagworte: | Y-27632 - 2HCL, (R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride |
| Anwendung: | ROCK kinase inhibitor |
| CAS | 129830-38-2 |
| MW: | 320.2 D |
ab 55,00 €
Progranulin (human) (rec.) (untagged)
Artikelnummer: AG-40A-0188Y-C050
Signal peptide and human progranulin (aa 1-593) is untagged. Reflects the native sequence with no additional aa. Activates phospho-ERK1/2 in neuronal mouse P19 cells. Regulates food intake and body weight. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as...
| Schlagworte: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Anwendung: | Cell culture |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 74 kD |
ab 220,00 €
Latrunculin B
Artikelnummer: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Schlagworte: | LAT-B, NSC 339663 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
ab 154,00 €
Anti-Caspase-1 (p10) (mouse), clone Casper-2
Artikelnummer: AG-20B-0044-C100
Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4...
| Schlagworte: | Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
462,00 €
Ganglioside GM1 . sodium salt (bovine brain)
Artikelnummer: AG-CN2-9000-M001
Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
| Schlagworte: | GM1 . Na, Monosialoganglioside GM1 . Na |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 37758-47-7 |
| MW: | 1545,8 D |
ab 110,00 €