Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Anti-TRAIL-R1 (human), clone HS101
Artikelnummer: AG-20B-0022-TRIAL
Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex...
| Schlagworte: | TRAIL Receptor 1, DR4, APO2, TNFRSF10A, CD261 |
| Anwendung: | FC, FA (Blocking), ICC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
160,00 €
Anti-TRAIL-R3 (human), clone HS301
Artikelnummer: AG-20B-0024-TRIAL
Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL...
| Schlagworte: | TRAIL Receptor 3, DcR1, TRID, TNFRSF10C, CD263 |
| Anwendung: | FC, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
160,00 €
Anti-TRAIL-R4 (human), clone HS402
Artikelnummer: AG-20B-0025-TRIAL
Recognizes human TRAIL-R4. Does not cross-react with human TRAIL-R1, -R2 or -R3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R4 is a receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL...
| Schlagworte: | TRAIL Receptor 4, TRUNDD, DcR2, TNFRSF10D, CD264 |
| Anwendung: | FC, ICC, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
160,00 €
Anti-TRAIL (human), clone HS501
Artikelnummer: AG-20B-0026-TRIAL
Recognizes human TRAIL. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TNF-related apoptosis-inducing ligand (TRAIL, Apo2L,CD253, TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved at the cell...
| Schlagworte: | Apo-2L, TNFSF10, CD253 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
160,00 €
Anti-TRAIL-R3 (human), clone TR3.06
Artikelnummer: AG-20B-0029-TRIAL
Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL...
| Schlagworte: | TRAIL Receptor 3, DcR1, TRID, TNFRSF10C, CD263 |
| Anwendung: | FC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
160,00 €
Anti-BAFF-R (mouse), clone 9B9
Artikelnummer: AG-20B-0034-TRIAL
Recognizes mouse BAFF-R. Liquid. In PBS containing 0.02% sodium azide. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
| Schlagworte: | BAFF Receptor, BR3, BlySR3, CD268, TNFRSF13C |
| Anwendung: | FC, Bioassays |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
160,00 €
Anti-TACI (mouse), clone 1A-10
Artikelnummer: AG-20B-0035-TRIAL
Recognizes mouse TACI. Liquid. In PBS containing 0.02% sodium azide. Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
| Schlagworte: | Transmembrane Activator and CAML Interactor, CD267, TNFRSF13B |
| Anwendung: | FC |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
160,00 €
Anti-BAFF (human), clone 1-35-1
Artikelnummer: AG-20B-0037-TRIAL
Recognizes human BAFF. Liquid. In PBS containing 0.02% sodium azide. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of...
| Schlagworte: | BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B |
| Anwendung: | FC |
| Wirt: | Rat |
| Spezies-Reaktivität: | human |
160,00 €
Anti-PIDD (mouse), clone Lise-1
Artikelnummer: AG-20B-0038-TRIAL
Recognizes mouse PIDD. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and...
| Schlagworte: | p53-induced protein with a death domain, Leucine-rich repeat and death domain-containing protein, Lrdd |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
160,00 €
Anti-NAIP1/2/5 (mouse), clone Naipa-1
Artikelnummer: AG-20B-0045-TRIAL
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to...
| Schlagworte: | Neuronal Apoptosis Inhibitory Protein 1, 2, 5, Baculoviral IAP Repeat-containing Protein 1a, 1b, 1e, Birc 1a, 1b, 1e |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
160,00 €
Anti-NLRP6/NALP6 (human), clone Clint-1
Artikelnummer: AG-20B-0046-TRIAL
The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to...
| Schlagworte: | NACHT-, LRR and PYD domains-containing Protein 6, Nod-like Receptor Pyrin Domain-containing Protein 6, NLRP6, Angiotensin... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
160,00 €
Anti-Notch1 (mouse), clone 22E5
Artikelnummer: AG-20B-0051-TRIAL
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development...
| Schlagworte: | Anti-Notch1, Anti-NOTCH-1, Anti-Notch ortholog 1, Anti-translocation-associated, Anti-TAN1, Anti-translocation-associated... |
| Anwendung: | FC |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
160,00 €