Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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2-Deoxy-D-glucose
Artikelnummer: AG-CR1-3681-G005
Non-metabolizable glucose analog. An indirect inhibitor of hexokinase (HK), inhibiting the rate limiting step of glycolysis and consequently decreases glycolysis. Inhibits phosphorylation of glucose by hexokinase, which consequently results in the depletion in cellular ATP, the inhibition of protein glycosylation...
| Schlagworte: | 2-Deoxyglucose, 2-Deoxy-D-arabinohexose, Ba2758, NSC 15293 |
| Anwendung: | Non-metabolizable glucose analog |
| CAS | 154-17-6 |
| MW: | 164.2 D |
ab 50,00 €
LY-294,002
Artikelnummer: AG-CR1-0108-M005
Potent, cell permeable, highly specific PI(3)K (phosphoinositide 3-kinase) inhibitor, Acts on the ATP-binding site of the enzyme, Antagonizes P-glycoprotein-mediated multidrug resistance, Blocks Akt phosphorylation, Pim-1 kinase inhibitor.
| Schlagworte: | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one, LY294002 |
| Anwendung: | PI3K inhibitor |
| CAS | 154447-36-6 |
| MW: | 307,4 D |
ab 22,00 €
Progranulin (mouse) ELISA Kit
Artikelnummer: AG-45A-0019YTP-KI01
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the...
| Schlagworte: | Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 671,00 €
Genipin
Artikelnummer: AG-CN2-0481-M100
White to off-white solid. Soluble in DMSO (50mg/ml), ethanol (5mg/ml), methanol or acetone. Slightly soluble in water. Cell permeable inhibitor of uncoupling protein 2 (UCP2), Increases glucose-stimulated insulin secretion, mitochondrial membrane potential and ATP levels in pancreatic island cells, Anticancer,...
| Schlagworte: | (+)-Genipin, Methyl (1S,2R,6S)-2-hydroxy-9-(hydroxymethyl)-3-oxabicyclo[4.3.0]nona-4,8-diene-5-carboxylate |
| Anwendung: | Cell permeable UCP2 inhibitor |
| CAS | 6902-77-8 |
| MW: | 226,2 D |
ab 61,00 €
Oxaliplatin
Artikelnummer: AG-CR1-3592-M005
White to off-white powder. Soluble in DMSO or water. Slightly soluble in methanol. Insoluble in ethanol. Potent platinum-based antineoplastic agent with wide spectrum anticancer activity, Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription...
| Schlagworte: | Diaminocyclohexane oxalatoplatinum, 1-OHP, ACT 078, RP 54780, NSC 266046 |
| Anwendung: | Apoptosis inducer, DNA crosslinker |
| CAS | 61825-94-3 |
| MW: | 397,3 D |
ab 39,00 €
(+)-Aphidicolin
Artikelnummer: BVT-0307-M005
Antibiotic, Reversible inhibitor of eukaryotic nuclear DNA replication, Useful for cell synchronization, Blocks the cell cycle at early S phase, Prolongs the half life of DNA methyltransferase, Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin, Acts...
| Schlagworte: | NSC234714, BRN4689958, ICI69653 |
| Anwendung: | Eukaryotic nuclear DNA replication inhibitor |
| CAS | 38966-21-1 |
| MW: | 338,5 D |
ab 75,00 €
6-ECDCA
Artikelnummer: AG-CR1-3560-M005
Potent and selective farnesoid X receptor FXR agonist (EC50= 99nM) [1]. Induces SHP in HSCs to suppress TIMP-1 expression [2]. Apoptosis inducer [2]. Protects against liver fibrosis development in rat in vivo [2]. Displays anticholeretic activity in rat in vivo [3]. Promotes preadipocyte differentiation [4]....
| Schlagworte: | 6alpha-Ethyl-chenodeoxycholic acid, 6-alpha-ECDC, Obeticholic acid, INT-747, OCA |
| Anwendung: | FXR agonist |
| CAS | 459789-99-2 |
| MW: | 420,3 D |
ab 22,00 €
Dynasore
Artikelnummer: AG-CR1-0045-M005
Dynamin GTPase inhibitor, Endocytosis inhibitor, Viral infection inhibitor, Destabilizes actin filaments, Inhibits entry of Trypanosoma into macrophages.
| Schlagworte: | 3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide . H2O |
| Anwendung: | Dynamin GTPase inhibitor |
| CAS | 304448-55-3 |
| MW: | 322,3 D |
ab 44,00 €
Anti-DLK1 (human), clone PF299-1
Artikelnummer: AG-20A-0070-C100
Recognizes human DLK1. Does not cross-react with mouse DLK1. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. DLK1 (Protein delta homolog 1, Preadipocyte factor 1, Pref-1) is a regulator of adipocyte differentiation found in serum and urine. DLK1 might be a decoy ligand. Serum or plasma...
| Schlagworte: | Protein Delta Homolog 1, Fetal Antigen 1, Preadipocyte Factor 1, Pref-1, FA1 |
| Anwendung: | ELISA, FC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 237,00 €
Anti-TRAIL-R2 (human), clone HS201
Artikelnummer: AG-20B-0023-C100
Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex...
| Schlagworte: | TRAIL Receptor 2, DR5, KILLER, TNFRSF10B, CD262 |
| Anwendung: | FC, FA (Blocking), ICC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
396,00 €
BAFF (60-mer), Soluble (human, rec.), highly active
Artikelnummer: AG-40B-0112-C010
Human BAFF (amino acids 134-285) is fused at the N-terminus to a His-tag. Lyophilized. Binds to human and mouse BAFF-R, TACI and BCMA. Relative binding affinity (EC50) for BAFF-R (human): 3ng/ml. Increases B cell survival /Proliferation. Increases CD21 / CD23 expression on B cells in vivo. Activates BAFF-R, TACI and...
| Schlagworte: | BLyS, TALL-1, CD257, B-cell activating factor, TNFSF 13B, Tumor necrosis factor ligand superfamily member 13B |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human, mouse |
ab 297,00 €
Enterocin
Artikelnummer: AG-CN2-0116-M001
Potent antibiotic. Bacteriocidin. Antibacterial. Broad spectrum activity against Gram-positive and Gram-negative bacteria.Herbicidal.Enterocin is a small molecular weight secondary metabolite and should not be confused with bacterial proteins isolated from Enterococci generically referred to as 'enterocins'.
| Schlagworte: | Vulgamycin |
| Anwendung: | Antibiotic |
| Wirt: | Streptomyces sp |
| CAS | 59678-46-5 |
| MW: | 444,4 D |
ab 66,00 €