Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Caspase-1 (mouse) matched antibody pair detection set
Artikelnummer: AG-46B-0003-KI01
Detects mouse Caspase-1 (p10 and p20 domain). Does not detect human Caspase-1. Contains sufficient materials to run ELISAs on 5 x 96-well plates. Sensitivity: 100 pg/ml. Contains standard protein, coating and detection antibodies and Streptavidin-HRP.
| Schlagworte: | ICE, p45, Casp1, Il1bc, CASP-1, IL-1BC, Caspase-1, EC=3.4.22.36, Caspase-1 subunit p10, Caspase-1 subunit p20, IL-1... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
715,00 €
Salinosporamide A
Artikelnummer: AG-CN2-0444-C100
Potent, irreversible inhibitor of all the 3 proteolytic activities of the mammalian 20S proteasome. beta5 subunit: chymotrypsin-like (EC50 = 3.5nM) beta2 subunit: trypsin-like (EC50 = 28nM) beta1 subunit: caspase-like or peptidyl-glutamyl peptide-hydrolyzing (PGPH) (EC50 = 430nM) Potent anticancer compound. Triggers...
| Schlagworte: | SalA, Marizomib, NPI-0052 |
| Anwendung: | Potent irreversible mammalian 20S proteasome subunit beta1/2/5 inhibitor |
| CAS | 437742-34-2 |
| MW: | 313,8 D |
ab 143,00 €
Asialo-GM1
Artikelnummer: AG-CN2-9008-M001
Semisynthetic. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions,...
| Schlagworte: | Ceramide tetrahexoside, Gangliotetraosylceramide, Asialoganglioside-GM1 |
| Anwendung: | Acidic glycosphingolipid |
| CAS | 71012-19-6 |
| MW: | 1255,6 D |
ab 215,00 €
![Anti-Poly(ADP-ribose) [PAR], clone 10H](https://www.biomol.com/media/image/36/96/a8/AG-20T-0001-C050_200x200.jpg "Anti-Poly(ADP-ribose) [PAR], clone 10H")
Anti-Poly(ADP-ribose) [PAR], clone 10H
Artikelnummer: AG-20T-0001-C050
Recognizes poly(ADP-ribose) synthesized by a broad range of PARPs (poly(ADP-ribose) polymerases), including human, mouse, rat or Drosophila PARP enzymes. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Processes such as transcription, repair and replication that require efficient DNA...
| Anwendung: | FC, ICC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | Drosophila, human, mouse, rat |
ab 231,00 €
Celastrol
Artikelnummer: AG-CN2-0460-M005
Red solid. Soluble in DMSO, ethanol or dimethylformamide. Insoluble in water. Anti-obesity agent. Potent leptin sensitizer, Antioxidant, Potent lipid peroxidation inhibitor, NADPH oxidases (NOX1, 2, 4 and 5) inhibitor, Anti-inflammatory. NF-kappaB inhibitor, HSP90 inhibitor and HSP70 inducer, Anticancer agent....
| Schlagworte: | Tripterine, NSC 70931 |
| Anwendung: | Antiobesity agent, 20S proteasome chymotrypsin-like activity inhibitor |
| CAS | 34157-83-0 |
| MW: | 450,6 D |
ab 55,00 €
N-Acetyl-D-glucosamine
Artikelnummer: AG-CN2-0489-G005
White to off-white solid. Soluble in DMSO (10mg/ml) or water. N-Acetyl-D-glucosamine (D-GlcNAc) is a non-toxic derivatized glucose monosaccharide found in polymers (Peptidoglycan, PGN) of bacterial cell walls, chitin (e.g. fungi, invertebrates, crustaceans), hyaluronic acids and various glycans. It is also...
| Schlagworte: | D-GlcNAc, GlcNAc, NAG, 2-(Acetylamino)-2-deoxy-D-glucose |
| Anwendung: | Cytoprotective agent |
| CAS | 7512-17-6 |
| MW: | 221,2 D |
ab 11,00 €
Troglitazone
Artikelnummer: AG-CR1-3565-M005
Potent and selective PPARgamma agonist with no activation of PPARalpha and PPARdelta. Anti-diabetic agent with potent glucose-lowering effects and decreasing insulin. resistance in adipose tissues. Stimulates adipogenesis. Apoptosis and cell cycle arrest inducer in several cancer cell lines. Inhibits vascular smooth...
| Schlagworte: | 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazlidinedione,... |
| Anwendung: | PPARgamma agonist |
| CAS | 97322-87-7 |
| MW: | 441,5 D |
72,00 €
Anti-Caspase-8 (human), clone C15
Artikelnummer: AG-20B-0057-C100
Recognizes the p18 subunit of human caspase-8. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized...
| Schlagworte: | Anti-Casp-8, Anti-CAP4, Anti-FADD-like ICE, EC=3.4.22.61 |
| Anwendung: | ICC, IP, WB |
| Wirt: | mouse |
| Spezies-Reaktivität: | human |
ab 264,00 €
(-)-Epigallocatechin gallate
Artikelnummer: AG-CN2-0063-M025
Potent anticancer compound - Anti-angiogenic. VEGF, VE-cadherin phosphorylation, matrix metalloproteinase and urokinase-plasminogen activator (uPA) inhibitor - Anti-inflammatory. NF-kappaB inhibitor. Modulates chronic inflammatory diseases, such as type 2 diabetes, rheumatoid arthritis, inflammatory bowel disease -...
| Schlagworte: | Epigallocatechin-3-gallate, CCRIS 3729, Teavigo, NVP-XAA 723 |
| Anwendung: | NF-kappaB inhibitor |
| Wirt: | green tea |
| CAS | 989-51-5 |
| MW: | 458,4 D |
ab 28,00 €
Colistin sulfate (USP Grade)
Artikelnummer: AG-CN2-0065-G001
Very potent polymyxin antibiotic - Has only one amino acid difference compared to polymyxin B - Antimicrobial - Targets the lipopolysaccharide (LPS) of the outer membrane of Gram-negative bacteria. Competitively displaces divalent cations (Ca2 and Mg2) from the negatively-charged phosphate groups LPS, causing...
| Schlagworte: | Polymyxin E, Belcomycin, Colimycin |
| Anwendung: | Antibiotic |
| Wirt: | Bacillus polymyxa |
| CAS | 1264-72-8 |
ab 39,00 €
Z-Leu-Leu-Glu-AMC
Artikelnummer: AG-CP3-0022-M005
Solid lyophilized powder. Soluble in DMSO. Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (PGPH) (caspase-like) activity of the 20S proteasome, Excitation: 380nm. Emission: 460nm.
| Schlagworte: | Z-LLE-AMC, Proteasome Substrate II |
| Anwendung: | Fluorogenic proteasome substrate |
| CAS | 348086-66-8 |
| MW: | 664,8 D |
ab 44,00 €
Carboplatin
Artikelnummer: AG-CR1-3591-M025
White to off-white powder. Soluble in water. Potent platinum-based antineoplastic agent. Analog of cisplatin (Prod. No. AG-CR1-3590) with reduced nephrotoxicity and higher stability, Antitumor agent, Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and...
| Schlagworte: | cis-Diammine(cyclobutane-1,1-dicarboxylate-O,O')platinum(II), NSC201345, NSC241240, JM-8, Paraplatin, Cbdca |
| Anwendung: | Apoptosis inducer, DNA crosslinker |
| CAS | 41575-94-4 |
| MW: | 371,3 D |
ab 39,00 €