Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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COMP (rat):Angiopoietin-1 (human) (rec.)
Artikelnummer: AG-40B-0147-C010
More potent than native angiopoietin-1. The protein forms tetrameric structures. The fibrinogen-like domain (aa 284-498) of human angiopoietin-1 is fused at the N-terminus to the coiled-coil domain of rat COMP (cartilage oligomeric matrix protein) and to a FLAG®-tag. Soluble, stable and more potent angiopoietin-1...
| Schlagworte: | ANG-1, ANGPT1, KIAA0003, Angiopoietin-1 |
| Anwendung: | Cell culture |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
| MW: | 25 kD |
ab 253,00 €
Vincristine . sulfate
Artikelnummer: AG-CN2-0446-M005
White to light-yellow powder. Soluble in water, DMSO or methanol. Immunosuppressant, Anticancer compound. Chemotherapeutic agent, Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins, Apoptosis inducer and cell cycle inhibitor in G2/M phase, Autophagy inhibitor. Inhibits...
| Schlagworte: | VCR, 22-Oxovincaleukoblastine, NSC 67574, Oncovin, Lilly 37231, Leucristine, Leurocristine, LS-228 |
| Anwendung: | Tubulin polymerization inhibitor |
| CAS | 2068-78-2 |
| MW: | 923,1 D |
ab 50,00 €
Triptolide
Artikelnummer: AG-CN2-0448-M010
Crystalline solid. Soluble in DMSO. Sparingly soluble in ethanol. Potent immunosuppressant with anti-inflammatory and antitumor properties, Exhibits potent antiproliferative activity, induces apoptosis, modulates autophagy and inhibits cell cycle regulators, Inhibits global gene transcription by inducing degradation...
| Schlagworte: | PG 490, NSC163062 |
| Anwendung: | Potent immunosuppressant, XPB inhibitor |
| CAS | 38748-32-2 |
| MW: | 360,4 D |
ab 28,00 €
COVID-19 Forschung
Leupeptin . Hemisulfate
Artikelnummer: AG-CP3-7000-M025
Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic...
| Schlagworte: | Acetyl-L-leucyl-L-leucyl-L-argininal . Hemisulfate |
| Anwendung: | Protease inhibitor, TMPRSS2 inhibitor |
| CAS | 103476-89-7 |
| MW: | 475.6 D |
ab 44,00 €
17-AAG
Artikelnummer: BVT-0244-M005
Potent, less toxic analog of geldanamycin, Inhibits the essential ATPase activity of HSP90, Telomerase activity inhibitor, Apoptosis inducer, Antitumor compound. Semi-synthetic derivative from geldanamycin.
| Schlagworte: | 17-(Allylamino)-17-desmethoxygeldanamycin |
| Anwendung: | Hsp90 inhibitor |
| CAS | 75747-14-7 |
| MW: | 585,7 D |
ab 25,00 €
Trypacidin
Artikelnummer: BVT-0442-M001
White to off-white solid. Soluble in DMSO, acetone or dichloromethane. Antibiotic, Antibacterial and antiprotozoal (trypanocidal), Toxic to human A549 lung cells, Necrosis inducer, Toxic to human bronchial epithelial cells, Stimulating the growth of corn seedling roots, Inhibits IL-6 secretion, collagen IV and...
| Anwendung: | Antibiotic, Antibacterial and antiprotozoal (trypanocidal) |
| CAS | 1900-29-4 |
| MW: | 344,3 D |
ab 125,00 €
Imiquimod
Artikelnummer: AG-CR1-3569-M250
Immune response modulator. Anti-inflammatory. TLR7 agonist. Stimulates proinflammatory cytokine production interferon-alpha (IFN-alpha), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) and activates NF-kappaB. Caspase-3 activator that directly induces procaspase-3 cleavage. Anti-cancer compound....
| Schlagworte: | 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline, S26308, R-837 |
| Anwendung: | TLR7 agonist |
| Wirt: | Synthetic |
| CAS | 99011-02-6 |
| MW: | 240,3 D |
ab 50,00 €
Necrosulfonamide
Artikelnummer: AG-CR1-3705-M005
Off-white to yellow solid. Soluble in DMSO (20mg/ml) or DMF (20mg/ml). Insoluble in water. Chemical. CAS: 1360614-48-7. Formula: C18H15N5O6S2. MW: 461.5. Inhibitor of necroptosis, by blocking mixed lineage kinase domain-like protein (MLKL), a key substrate of receptor-interacting serine-threonine kinase 3 (RIP3)....
| Schlagworte: | NSA, (2E)-N-[4-[[(3-methoxy-2-pyrazinyl)amino]sulfonyl]phenyl]-3-(5-nitro-2-thienyl)-2-propenamide |
| Anwendung: | Necroptosis inhibitor, MLKL inhibitor |
| CAS | 1360614-48-7 |
| MW: | 461,5 D |
ab 50,00 €
Adiponectin (rat, rec.)
Artikelnummer: AG-40A-0004Y-C050
Rat adiponectin (amino acids 16-244) is fused at the N-terminus to a FLAG(R)-tag. Induces the phosphorylation of acetyl-CoA carboxylase (ACC) in C2C12 cells. Liquid. 0.2µm-filtered solution in 30mM TRIS-Cl, pH 8.5. ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural...
| Schlagworte: | ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30kDa |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | rat |
| MW: | 30 kD |
396,00 €
Merafloxacin
Artikelnummer: AG-CR1-3756-M005
Merafloxacin is a fluoroquinolone broad-spectrum antibacterial compound. It is an inhibitor of bacterial DNA gyrase and Type II DNA topoisomerase. It demonstrated excellent activity against Gram-positive organisms and less potent activity against Gram-negative bacteria. Merafloxacin is a programmed -1 ribosomal...
| Schlagworte: | CI-934, PD 114843, 1-Ethyl-7-(3-((ethylamino)methyl)-1-pyrrolidinyl)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic... |
| Anwendung: | Antibacterial, Ribosomal frameshifting SARS-CoV-2 inhibitor |
| CAS | 91188-00-0 |
| MW: | 379,4 D |
ab 88,00 €
Anti-IL-1alpha (p18) (mouse), clone Teo-1
Artikelnummer: AG-20B-0064-C100
Protein function: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to...
| Schlagworte: | Anti-Il1a, Anti-IL-1 alpha, Anti-Interleukin-1 alpha |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
176,00 €
Anti-Fis1
Artikelnummer: AG-25B-0007V-C100
1 mg/ml. Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission. Protein function: Involved in the fragmentation of the mitochondrial...
| Schlagworte: | Anti-FIS1, Anti-TTC11, Anti-hFis1, Anti-CGI-135, Anti-FIS1 homolog, Anti-TPR repeat protein 11, Anti-Mitochondrial fission... |
| Anwendung: | ICC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
369,00 €