Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Anti-Asc (AL177) (preservative free)
Artikelnummer: AG-25B-0006PF-C100
Recognizes human and mouse Asc. Liquid. From rabbit. Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the...
| Schlagworte: | Anti-ASC, Anti-TMS1, Anti-hASC, Anti-CARD5, Anti-PYCARD, Anti-PYD and CARD domain-containing protein, Anti-Target of... |
| Anwendung: | FA, ICC, IHC, IP, WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
462,00 €
Anti-APRIL (mouse), mAb (rec.) (blocking) (Apry-1-1)...
Artikelnummer: AG-27B-0001PF-C100
APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-1) is an antibody developed by...
| Schlagworte: | Anti-Tnfsf13, Anti-A proliferation-inducing ligand, Anti-Tumor necrosis factor ligand superfamily member 13, Anti-CD256,... |
| Anwendung: | ELISA, FA (Blocking), IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
ab 429,00 €
Lactacystin
Artikelnummer: AG-CN2-0104-C100
Induces neuritogenesis, Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP, multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit, apoptosis inducer, anticancer compound, upregulates HSP70 and HSP22, induces differentiation and...
| Anwendung: | Irreversible proteasome inhibitor |
| CAS | 133343-34-7 |
| MW: | 376,4 D |
ab 77,00 €
BAY 58-2667 . hydrochloride
Artikelnummer: AG-CR1-3509-M001
Nitric oxide (NO)- and heme-independent soluble guanylyl cyclase activator. Shows potent cardiovascular effects. Improves cardiopulmonary hemodynamics in patients with acute decompensated heart failure. Exhibits potent vasodilator and antiplatelet activity. Anti-aggregating agent.
| Schlagworte: | Cinaciguat . hydrochloride |
| Anwendung: | Soluble guanylyl cyclase activator |
| CAS | 1240669-95-7 |
| MW: | 565,6 D |
99,00 €
Beauvericin
Artikelnummer: AG-CN2-0043-M001
Antibiotic. Apoptosis inducer. Acyl-CoA:cholesterol acyltransferase inhibitor. Anticancer compound. Antihaptotactic and antimetastatic. Antiangiogenic compound. Antibacterial, antiprotozal, antiviral and antifungal compound. Shows ionophoric properties. Cytotoxic. Genotoxic. Potently interacts with ABCB1 and ABCG2...
| Anwendung: | Apoptosis inducer |
| Wirt: | Beauveria sp. |
| CAS | 26048-05-5 |
| MW: | 784 kD |
ab 39,00 €
AICAR
Artikelnummer: AG-CR1-0061-M010
Soluble in water (9 mg/ml), DMSO or dimethyl formamide. Cell permeable AMP-activated protein kinase (AMPK) activator. Insulin mimetic. Adipocyte differentiation inhibitor. Apoptosis inducer. PPARalpha inhibitor. mTOR inhibitor. P70S6K inhibitor. LPS-induced TNF-alpha production inhibitor. TORC2 phosphorylation...
| Schlagworte: | 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside |
| Anwendung: | AMPK activator |
| CAS | 2627-69-2 |
| MW: | 258,2 D |
ab 33,00 €
AdipoRon
Artikelnummer: AG-CR1-0154-M010
Soluble in DMSO, 100% ethanol or methanol. Insoluble in water. Orally-active adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 at low ?m concentration. Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells. Activates peroxisome proliferator-activated...
| Schlagworte: | 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide |
| Anwendung: | Adiponectin receptor agonist |
| CAS | 924416-43-3 |
| MW: | 428,5 D |
ab 66,00 €
Simocyclinone D8
Artikelnummer: BVT-0290-M001
Antibiotic, Bacterial DNA gyrase inhibitor: Staphylococcus aureus (IC50= 1.45µM), E.coli (IC50= 0.41µM), Human topoisomerase II (Topo II) inhibitor (IC50= 100µM), Antibacterial (Gram-positive), Antitumor compound. Isolated from Streptomyces antibioticus Tü 6040.
| Anwendung: | Bacterial DNA gyrase inhibitor, Human topoisomerase II (Topo II) inhibitor |
| CAS | 301845-97-6 |
| MW: | 932,3 D |
120,00 €
IL-33 (human, rec.) (His)
Artikelnummer: AG-40A-0042-C050
Human IL-33 (amino acids 112-270) is fused at the C-terminus to a His-tag. Activates human ST2-dependent NF-kappaB pathway. Liquid. 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell...
| Schlagworte: | Interleukin-33, IL-1F11, NF-HEV |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 18 kD |
ab 149,00 €
Ionomycin (free acid)
Artikelnummer: AG-CN2-0416-M001
Pale yellow liquid. Soluble in methanol or DMSO. Antibiotic, Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators, Ionomycin also transports Pb2+ and some other divalent...
| Schlagworte: | Antibiotic SQ 23377, EM 94 |
| Anwendung: | Antibiotic, Potent and highly selective Ca2+ ionophore |
| CAS | 56092-81-0 |
| MW: | 709,0 D |
ab 77,00 €
BAY 43-9006
Artikelnummer: AG-CR1-0025-M005
Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review.
| Schlagworte: | Sorafenib, N-[4-Chloro-3-(trifluoromethyl)phenyl]-([4-[2-(N-methylcarbamoyl)(4-pyridyloxy)]phenyl]amino)-carboxamide |
| Anwendung: | Raf kinase inhibitor |
| CAS | 284461-73-0 |
| MW: | 464,8 D |
ab 17,00 €
Aureothin
Artikelnummer: BVT-0303-M001
Oxidoreductase inhibitor, Antitrypanosomal, antibacterial, antifungal, insecticidal and pesticidal, Antitumor compound. Isolated from Streptomyces thioluteus.
| Schlagworte: | Mycolutein, Distacin, JA 2814K, Antibiotic 74A, BRN 0058476 |
| Anwendung: | Oxidoreductase inhibitor |
| CAS | 2825-00-5 |
| MW: | 397,4 D |
ab 235,00 €