Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Sclerotiorin
Artikelnummer: AG-CN2-0054-M001
Antibacterial, weak antagonist of human endothelin receptor A (ETA) and B (ETB), Cholesteryl ester transfer protein (CETP) activity inhibitor, Grb2-Shc binding inhibitor, potent aldose reductase inhibitor, potent reversible, non-competitive soybean lipoxygenase-1 (LOX-1) inhibitor, antioxidant. Free radical...
| Schlagworte: | (S-(R*,R*-(E,E)))-Sclerotiorin |
| Anwendung: | Lox-1 inhibitor |
| CAS | 549-23-5 |
| MW: | 390,9 D |
ab 99,00 €
Luteolin
Artikelnummer: AG-CN2-0098-M005
Yellow solid. Soluble in DMSO, DMF, methanol or ethanol. Slightly soluble in water. Anticancer and antimetastatic, alpha-Glucosidase inhibitor, Topoisomerase I Inhibitor, Apoptosis inducer, Anti-inflammatory, 15-Lipoxygenase (15-LOX) inhibitor, IL-6 production inhibitor, Fatty acid synthase (FAS) inhibitor,...
| Schlagworte: | 3',4',5,7-Tetrahydroxyflavone, Luteolol, BRN 0292084, C.I. Natural Yellow 2, Digitoflavone, Flacitran, Flavopurpol,... |
| Anwendung: | 15-LOX inhibitor |
| CAS | 491-70-3 |
| MW: | 286,2 D |
ab 22,00 €
DAPT
Artikelnummer: AG-CR1-0016-M005
Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42), Reduces Abeta levels in vivo, Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD), Does not inhibit persenilinase, Notch processing inhibitor, Enhances...
| Schlagworte: | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432,5 D |
ab 77,00 €
6BIO
Artikelnummer: AG-CR1-0056-M001
Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
| Schlagworte: | 2Z,3E)-6-Bromoindirubin-3-oxime |
| Anwendung: | PDPK1 inhibitor |
| CAS | 667463-62-9 |
| MW: | 356,2 D |
ab 39,00 €
MnTBAP chloride
Artikelnummer: AG-CR1-0133-M050
Cell permeable superoxide dismutase (SOD) mimetic, Potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO), Neuronal apoptosis inhibitor, Protects T cells from superoxide generation, caspase-dependent DNA loss and cell death,...
| Schlagworte: | Manganese (III) tetrakis (4-benzoic acid)porphyrin chloride |
| Anwendung: | SOD mimetic |
| MW: | 879,2 D |
ab 28,00 €
Anti-Neutrophils (mouse), blocking, clone Nimp-R14...
Artikelnummer: AG-20B-0043PF-M002
Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse...
| Anwendung: | FC, IHC, ICC, FA (Blocking) |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
ab 319,00 €
Jagged-1 (human):Fc (human, rec.)
Artikelnummer: AG-40A-0081-C050
Signal peptide and extracellular domain of human Jagged-1 (HJ1, CD339) (amino acids 1-1067) are fused at the C-terminus to the Fc portion of human IgG1. Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells. Liquid. 0.2µm-filtered solution in PBS. Jagged-1 is a ligand for multiple...
| Schlagworte: | Protein Jagged-1, hJ1, CD339, JAG1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 150 kD |
ab 242,00 €
Sterigmatocystin
Artikelnummer: BVT-0171-M001
Isolated from Aspergillus sp. (strain WDMH51). Soluble in DMSO, ethanol, methanol, pyridine or acetone. Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor....
| Schlagworte: | NSC 201423, NSC 204986 |
| Anwendung: | DNA synthesis inhibitor |
| CAS | 10048-13-2 |
| MW: | 324,3 D |
ab 60,00 €
Liraglutide
Artikelnummer: AG-CP3-0034-M001
Long-acting acylated glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic and antiobesity agent used clinically to treat type 2 diabetes mellitus. Binding to GLP-1R, activates AMP-activated protein kinase, consequently stimulates insulin secretion in pancreatic beta cells and suppresses glucagon secretion...
| Schlagworte: | Arg34Lys26-(N-?-(?-Glu(N-?-hexadecanoyl)))-GLP-1(7-37), NN2211, NNC 90-1170, Victoza |
| Anwendung: | GLP-1 receptor agonist |
| CAS | 204656-20-2 |
| MW: | 3751.2 D |
ab 55,00 €
Everolimus
Artikelnummer: AG-CN2-0520-M001
White to off-white solid. Soluble in DMSO (50mg/ml), ethanol (50mg/ml), methanol or DMF. Insoluble in water. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that...
| Schlagworte: | 42-O-(2-Hydroxyethyl)rapamycin, NVP-RAD001, RAD001, SDZRAD, Zortress, Afinitor, Certican, Votubia |
| CAS | 159351-69-6 |
| MW: | 958,2 D |
ab 36,00 €
Remdesivir
Artikelnummer: AG-CR1-3713-M025
Soluble in DMSO (50mg/ml). Remdesivir is an adenosine triphosphate analog with broad-spectrum antiviral activity. It is a prodrug that metabolizes into its active form GS-441524 (Prod. No. AG-CR1-3722). GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of...
| Schlagworte: | GS-5734 |
| Anwendung: | Antiviral, Adenosine triphosphate analog |
| CAS | 1809249-37-3 |
| MW: | 602.6 D |
ab 77,00 €
Anti-beta-Tubulin (beta-monoE), pAb (IN115)
Artikelnummer: AG-25B-0039-C050
Polyglutamylation is an evolutionarily conserved protein post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. The most prominent substrate is tubulin, the building block of microtubules (MTs). Polyglutamylation has been found on both, alpha- and...
| Schlagworte: | Anti-TUBB2, Anti-TUBB2A, Anti-Tubulin beta-2A chain, Anti-Tubulin beta class IIa |
| Anwendung: | WB, ICC, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
429,00 €