Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Semaglutide . AcOH
Artikelnummer: AG-CP3-0032-M025
Solid lyophilized powder. Soluble in aqueous solution (5% AcOH) (1mg/ml). Chemical. CAS: 910463-68-2 (parent). Formula: C187H291N45O59 . C2H4O2. MW: 4113.6 . 60.0. Synthetic. Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon...
| Schlagworte: | NN 9535, NNC 0113-0217, Ozempic |
| Anwendung: | GLP-1 receptor agonist |
| MW: | 4173.6 D |
ab 61,00 €
COVID-19 Forschung
GS-441524 (Remdesivir Metabolite)
Artikelnummer: AG-CR1-3722-M050
Soluble in DMSO (10mg/ml) or DMF (10mg/ml). GS-441524 is the active metabolite of the broad-spectrum antiviral Remdesivir. GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of...
| Anwendung: | Antiviral nucleoside analog, active remdesivir metabolite |
| CAS | 1191237-69-0 |
| MW: | 291.3 D |
ab 55,00 €
Anti-Fibronectin (EDA), mAb (blocking) (IST-9)...
Artikelnummer: AG-20B-6001YPF-C100
Fibronectin is a major component of the extracellular matrix that binds to integrins, cell surfaces and various compounds including collagen, fibrin, heparin, DNA and actin. It occurs in two main forms: plasma and cellular fibronectin. EDA (Extra Domain A)-containing cellular fibronectin (EDA-FN) plays a major role...
| Schlagworte: | FN, Cold-insoluble Globulin, CIG, Fibronectin (EIIIA) |
| Anwendung: | ELISA, FUNC (Blocking), ICC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | chicken, bovine, dog, human, monkey, mouse, swine, rat |
ab 308,00 €
Anti-TRAIL-R3 (human), clone TR3.06
Artikelnummer: AG-20B-0029-C100
Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL...
| Schlagworte: | TRAIL Receptor 3, DcR1, TRID, TNFRSF10C, CD263 |
| Anwendung: | FC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
396,00 €
Angiopoietin-2 (human) (rec.)
Artikelnummer: AG-40B-0114-3010
Human angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG-tag. Lyophilized. Contains PBS with trehalose and Brij35. Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical...
| Schlagworte: | Ang-2, Ang2, Angpt2 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 70 kD |
ab 226,00 €
Convulxin
Artikelnummer: AG-CN2-0465-C050
Lyophilized. Soluble in organic buffer (HEPES). Glycoprotein GPVI receptor agonist. Can be used for studies on platelet receptors, Activates mammalian platelets via binding and clustering of GPVI-receptors under physiological conditions. Occupation and clustering of GPVI activates Src family kinases, phosphorylates...
| Schlagworte: | CVX |
| Anwendung: | Glycoprotein VI GP6 receptor agonist |
| CAS | 37206-04-5 |
| MW: | 84 kD |
1.210,00 €
(+)-Brefeldin A
Artikelnummer: BVT-0190-M001
Protein transport from ER to Golgi inhibitor, ADP-ribosylation factor (Arf) inhibitor, Cytotoxic, Antibiotic, Antiviral, Apoptosis inducer, Antitumor compound, Intracellular collagen degradation inhibitor. Isolated from Eupenicillium brefeldianum.
| Schlagworte: | Ascotoxin, Decumbin |
| Anwendung: | Protein transport from ER to Golgi inhibitor, ADP-ribosylation factor (Arf) inhibitor |
| CAS | 20350-15-6 |
| MW: | 280,4 D |
45,00 €
Swinholide A
Artikelnummer: AG-CN2-0035-C050
Isolated from marine sponge Theonella swinhoei. Cell permeable dimeric dilactone macrolide - Cytotoxic compound - Specific actin filament (F-actin) inhibitor - Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin) - Depolymerizes actin filaments (F-actin) -...
| Anwendung: | F-actin depolymerization |
| CAS | 95927-67-6 |
| MW: | 1389,9 D |
ab 108,00 €
Jasplakinolide
Artikelnummer: AG-CN2-0037-C050
Isolated from Jaspis splendens. Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for...
| Schlagworte: | Jaspamide, NSC 613009 |
| Anwendung: | Actin polymerization inducer |
| CAS | 102396-24-7 |
| MW: | 709,7 D |
ab 275,00 €
(R)-Roscovitine
Artikelnummer: AG-CR1-0006-M005
Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in G1 phase, Antitumor compound, Activates the mitogen-activated...
| Schlagworte: | 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine |
| Anwendung: | CDK inhibitor |
| CAS | 186692-46-6 |
| MW: | 354,5 D |
ab 33,00 €
Venturicidin A
Artikelnummer: BVT-0454-M001
White solid. Soluble in DMSO, methanol, acetone or dichloromethane. Insoluble in hexane or water. 20-Membered macrolide glycoside, Antibiotic and antifungal agent, Shows antitrypanosomal and antimalarial activity, Potent inhibitor of mitochondrial and bacterial ATP synthase, Inhibitor of F0F1-ATPase,...
| Schlagworte: | Aabomycin A1 |
| Anwendung: | Macrolide antibiotic, F0F1-ATPase inhibitor |
| CAS | 33538-71-5 |
| MW: | 750,0 D |
135,00 €
Terrein
Artikelnummer: BVT-0193-M010
Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion...
| Schlagworte: | NSC 291308, 4,5-Dihydroxy-3-(1-propenyl)-2-cyclopenten-1-one |
| Anwendung: | Antibacterial, Phytotoxin |
| CAS | 582-46-7 |
| MW: | 154,2 D |
ab 125,00 €