Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Epoxomicin
Artikelnummer: AG-CN2-0422-C100
White to off-white solid. Soluble in DMSO. Insoluble in water. Antibiotic, Potent anticancer compound, Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome...
| Schlagworte: | Antibiotic BU 4061T |
| Anwendung: | Antibiotic, anticancer compound, Cell-permeable irreversible 20S proteasome inhibitor |
| CAS | 134381-21-8 |
| MW: | 554,7 D |
ab 83,00 €
D-erythro-Dihydrosphingosine 1-phosphate
Artikelnummer: AG-CR1-0005-M001
Saturated analog of sphingosine 1-phosphate (1-SP1), Ligand for sphingosine 1-phophate (S1P/EDG) receptors, Negative control for intracellular effects of sphingosine 1-phosphate, Induces chemotaxis, Antifibrotic.
| Schlagworte: | (2S,3R)-Dihydro-sphingosine 1-phosphate, Dihydro-S1P, dhS1P |
| Anwendung: | Bioassays |
| MW: | 381,5 D |
ab 105,00 €
JC-10 (high purity)
Artikelnummer: AG-CR1-3600-M005
Deep blue to violet solid. Soluble in water or DMSO. JC-10 is superior analog of JC-1, useful for determining mitochondrial membrane potential (MMP) in cells by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-10 is a cationic, lipophilic dye that accumulates in mitochondria of...
| Schlagworte: | Enhanced JC-1 |
| Anwendung: | Mitochondrial function assays |
| MW: | 600 D |
ab 83,00 €
Progranulin (human) (rec.)
Artikelnummer: AG-40A-0068Y-C050
Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...
| Schlagworte: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Anwendung: | Cell culture |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 76 kD |
ab 187,00 €
Astaxanthin
Artikelnummer: AG-CN2-0055-M025
Potent antioxidant carotenoid. Free radical scavenger. Reduces oxidative stress. Anticancer compound. Anti-inflammatory. Blocks NF-kappaB activatin. Anti-hypertensive. Cardiovascular protective. Improves neuronal stem cell potential. Neuroprotective. Inhibits tumor invasion. Apoptosis inducer. Increases insulin...
| Schlagworte: | all-trans-Astaxanthin, Ovoester, NSC635689, 3,3'-Dihydroxy-beta-carotene-4,4'-dione, CCRIS 7118, HSDB 7468 |
| Anwendung: | Antioxidant |
| CAS | 472-61-7 |
| MW: | 596,8 D |
ab 50,00 €
COVID-19 Forschung
Ebselen
Artikelnummer: AG-CR1-0031-M025
Glutathione peroxidase mimetic, Peroxynitrite scavenger, Anti-inflammatory Antioxidant, Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+ATPase and NADPH oxidase inhibitor, Antifungal, Review.
| Schlagworte: | 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one |
| Anwendung: | Antioxidant, Glutathione peroxidase mimetic |
| CAS | 60940-34-3 |
| MW: | 274,2 D |
ab 18,00 €
Necrostatin-1
Artikelnummer: AG-CR1-2900-M005
Synthetic. Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase...
| Schlagworte: | Nec-1, MTH-Trp, MTH-DL-Tryptophan, Methyl-thiohydantoin DL-tryptophan,... |
| Anwendung: | IDO inhibitor |
| CAS | 4311-88-0 |
| MW: | 259,3 D |
ab 44,00 €
DLL1 (human):Fc (human) (rec.)
Artikelnummer: AG-40A-0116Y-C010
Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and...
| Schlagworte: | DLL1, Delta1, H-Delta-1, Delta-like protein 1, Drosophila Delta homolog |
| Anwendung: | Bioassay |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
| MW: | 100 kD |
ab 253,00 €
Ionomycin . calcium salt
Artikelnummer: AG-CN2-0418-M001
White to off-white solid. Soluble in DMSO, ethanol or methanol. Antibiotic, Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators, Ionomycin also transports Pb2+ and some...
| Schlagworte: | Antibiotic SQ 23377, EM 94 |
| Anwendung: | Antibiotic, Potent and highly selective Ca2+ ionophore |
| CAS | 56092-82-1 |
| MW: | 747,1 D |
ab 72,00 €
Cucurbitacin B
Artikelnummer: AG-CN2-0472-M001
Off-white powder. Soluble in DMSO. Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation, Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties, Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell...
| Schlagworte: | Cuc B, 1,2-Dihydro-alpha-elaterin, Amarine, NSC 49451, NSC 144154 |
| Anwendung: | Microtubule polymerization inhibitor |
| CAS | 6199-67-3 |
| MW: | 558,7 D |
ab 39,00 €
Pioglitazone
Artikelnummer: AG-CR1-0067-M005
Thiazolidinedione (TZD) reference compound, Selective PPARgamma agonist, Selectively activates PPARgamma-1, Anti-diabetic , decreasing insulin resistance in adipose tissue, Is about one tenth as potent as rosiglitazone, Lipid metabolism modulator, Estrogen synthesis inhibitor, NF-kappaB inhibitor, Neuroprotective.
| Schlagworte: | 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 111025-46-8 |
| MW: | 356,4 D |
ab 22,00 €
Pseudouridimycin
Artikelnummer: AG-CN2-0316-M001
Isolated from Streptomyces sp. Off-white to yellow powder. Soluble in DMSO or water. Peptidyl nucleoside antibiotic. Selective nucleoside-analog inhibitor of bacterial RNA polymerase (RNAP). Inhibits RNAP through a distinctive binding site on RNAP (the NTP addition site) and mechanism (competition with UTP for...
| Schlagworte: | PUM |
| Anwendung: | Antibiotic, Bacterial RNA polymerase inhibitor |
| CAS | 1566586-52-4 |
| MW: | 486.4 D |
ab 171,00 €