Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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TIGIT (human):Fc (human) (rec.)
Artikelnummer: AG-40B-0162-C050
The extracellular domain of human TIGIT (aa 22-138) is fused at the C-terminus to the Fc portion of human IgG1. TIGIT (T cell immunoreceptor with Ig and ITIM domains) is a novel member of the immunoglobulin super family (IgSF). TIGIT and CD226 bind the same ligands, the two nectin-family members poliovirus receptor...
| Schlagworte: | TIGIT, VSIG9, T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, V-set... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~40-45 kD |
352,00 €
VISTA [B7-H5] (human):Fc (human) (rec.)
Artikelnummer: AG-40B-0163-C050
The extracellular domain of human VISTA (aa 33-194) is fused at the C-terminus to the Fc portion of human IgG1. Human VISTA is a 55- to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on...
| Schlagworte: | Sisp-1, PP2135, C10orf54, Platelet receptor Gi24, Stress-induced secreted protein-1, V-set domain-containing... |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | ~65-70 kD |
330,00 €
IL-36alpha (aa 6-158) (human) (rec.) (untagged)
Artikelnummer: AG-40B-0165-3010
Human IL-36alpha (aa Lys6-Phe158) is untagged. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including...
| Schlagworte: | FIL1E, IL36A, IL-1F6, FIL1 epsilon, IL-1 epsilon, Interleukin-36 alpha, Interleukin-1 epsilon, Interleukin-1 family member 6 |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | ~17 kD |
ab 204,00 €
IL-36gamma (aa 18-169) (human) (rec.) (untagged)
Artikelnummer: AG-40B-0166-3010
Human IL-36gamma (aa Ser18-Asp169) is untagged. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including...
| Schlagworte: | IL1E, IL36G, IL-1H1, IL-1F9, IL-1RP2, IL-1 epsilon, Interleukin-36 gamma, Interleukin-1 epsilon, IL-1-related protein 2,... |
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | ~17 kD |
ab 215,00 €
Slit2 (C fragment) (human) (rec.)
Artikelnummer: AG-40B-0168-3010
The Slits are secreted proteins that bind to Robo receptors and play a role in axon guidance and neuronal migration. The Slit family in mice and humans comprises three members: Slit1, Slit2 and Slit3. These are all extracellular matrix proteins of 180-200kDa. In vivo, Slit2 is cleaved into 140kDa N-terminal...
| Schlagworte: | SLIT2, SLIL3 |
| MW: | ~55 kD |
ab 127,00 €
VISTA [B7-H5] (human) (rec.) (His)
Artikelnummer: AG-40B-0177-3010
Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with lower expression on CD4+ and CD8+ T cells. VISTA is a new negative checkpoint regulator that...
| Schlagworte: | V-type Immunoglobulin Domain-containing Suppressor of T Cell Activation, Platelet Receptor Gi24, Stress-induced Secreted... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 3040 kD |
ab 165,00 €
PARP-1 [ARTD1] (E988K Mutant) (human) (rec.) Control
Artikelnummer: AG-40T-0015-C010
Human full-length inactive mutant E998K of PARP-1 is fused to a HA-tag and a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a...
| Schlagworte: | ADPRT, ARTD1, PARP1, PARP-1, ADPRT 1, EC=2.4.2.30, Poly[ADP-ribose] synthase 1, Poly [ADP-ribose] polymerase 1, NAD(+)... |
| Anwendung: | Negative control |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
160,00 €
GCN5 (human) (rec.) (His) (highly active)
Artikelnummer: AG-40T-0017-C002
Human GCN5 is fused to a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription...
| Schlagworte: | GCN5, KAT2A, HsGCN5, STAF97, EC=2.3.1.48, Lysine acetyltransferase 2A, Histone acetyltransferase GCN5, Histone... |
| Anwendung: | HAT enzyme assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
242,00 €
TIP60 (human) (rec.) (His) (highly active)
Artikelnummer: AG-40T-0019-C002
Human TIP60 is fused to a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation...
| Schlagworte: | KAT5, Tip60, HTATIP, EC=2.3.1.48, Lysine acetyltransferase 5, cPLA(2)-interacting protein, HIV-1 Tat interactive protein,... |
| Anwendung: | HAT enzyme assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
220,00 €
NF-kB (p65) (human) (rec.) (His) (highly active)
Artikelnummer: AG-40T-0020-C002
Human NF-kappaB (p65) is fused to a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol. NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are...
| Schlagworte: | RELA, NFKB3, Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide... |
| Anwendung: | EMSA, Transcription assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
253,00 €
EGFR, Soluble (human) (rec.)
Artikelnummer: AG-40T-0041-C025
Human EGFR (629aa) is fused at the C-terminus to a Strep-tag. Lyophilized. EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR...
| Schlagworte: | EGFR, ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1 |
| Anwendung: | Bioassay |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 85 kD |
495,00 €
VEGF-C (human) (rec.) (His)
Artikelnummer: AG-40T-0046-C020
Human VEGF-C (115aa) is fused at the C-terminus to a His-tag. Lyophilized. VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in...
| Schlagworte: | VRP, VEGFC, Flt4-L, VEGF-C, Flt4 ligand, Vascular endothelial growth factor C, Vascular endothelial growth factor-related... |
| Anwendung: | Bioassay |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 18-24 kD |
495,00 €