Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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MS-275
Artikelnummer: AG-CR1-0032-M001
HDAC 1 inhibitor, Antitumor compound, Antiproliferative, TGF-beta type II receptor inducer, Apoptosis inducer, Anti-inflammatory, Angiogenesis inhibitor, Review.
| Schlagworte: | N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxy-carbonyl)aminomethyl]benzamide, MS-27-275 |
| Anwendung: | HDAC 1 inhibitor |
| CAS | 209783-80-2 |
| MW: | 376,4 D |
ab 17,00 €
IBMX
Artikelnummer: AG-CR1-3512-M500
Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
| Schlagworte: | 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3 |
| Anwendung: | Phosphodiesterase inhibitor |
| CAS | 28822-58-4 |
| MW: | 222,3 D |
ab 121,00 €
Menadione
Artikelnummer: AG-CR1-3631-G001
Off-white to yellow solid. Soluble in DMSO (20mg/ml), ethanol (10mg/ml) or dimethylformamide (30mg/ml). Insoluble in water. Synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2 (menaquinone) after alkylation in vivo. The 1,4-naphthoquinone (NQ)...
| Schlagworte: | Vitamin K3, NSC4170, 2-Methyl-1,4-naphthalenedione |
| Anwendung: | Anticancer compound, Apoptosis inducer |
| CAS | 58-27-5 |
| MW: | 172,2 D |
ab 22,00 €
Anti-BAFF (mouse), clone Sandy-2 (blocking) (preservative...
Artikelnummer: AG-20B-0063PF-C500
BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's...
| Schlagworte: | Anti-Baff, Anti-Tnfsf13b |
| Anwendung: | FA, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
ab 462,00 €
X-Gal
Artikelnummer: AG-CC1-0003-G001
Chromogenic substrate for beta-galactosidase, Used in gene cloning (together with IPTG (Prod. No. AG-CC1-0002) to indicate whether a cell expresses the beta-galactosidase enzyme, which is encoded by the lacZ gene, in a technique called blue/white screening, Distinguishes between recombinant and non-recombinant...
| Schlagworte: | 5-Bromo-4-chloro-3-indolyl beta-D-galactoside |
| Anwendung: | beta-galactosidase substrate |
| CAS | 7240-90-6 |
| MW: | 408,6 D |
ab 28,00 €
LAG-3 (human):Fc (human, rec.)
Artikelnummer: AG-40B-0031-C050
The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1. Liquid. In PBS. Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in...
| Schlagworte: | Lymphocyte Activation Gene-3, FDC Protein, CD223 |
| Anwendung: | Bioassays |
| Exprimiert in: | CHO cells |
| Ursprungsart: | human, monkey, mouse |
| MW: | 80 kD |
363,00 €
Heptelidic acid
Artikelnummer: AG-CN2-0118-M001
Antibiotic - Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH - Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation - Antimalarial - Apoptosis inhibitor....
| Schlagworte: | Koningic acid, Avocettin, FO-4443, BRN 5091359 |
| Anwendung: | Antibiotic |
| Wirt: | Trichoderma sp |
| CAS | 74310-84-2 |
| MW: | 280,3 D |
ab 143,00 €
Aspterric acid
Artikelnummer: AG-CN2-0132-M001
Isolated from Penicillium sp. Antibiotic. Pollen growth and development inhibitor.
| Anwendung: | Antibiotic |
| CAS | 67309-95-9 |
| MW: | 266,3 D |
198,00 €
Boromycin
Artikelnummer: AG-CN2-0166-M001
Off-white solid. Soluble in DMSO, ethanol or methanol. Boron containing macrolide antibiotic, Antibacterial, Antiprotozoal (Plasmodium, Babesia), Anti-HIV compound, Ca2+ homeostasis modulator, Potentiator of bleomycin-induced anti-tumor activity, Used as a chiral selector in capillary electrophoresis.
| Schlagworte: | Antibiotic A 28829, Ivomycin, NSC216128 |
| Anwendung: | Antibiotic |
| CAS | 34524-20-4 |
| MW: | 879,9 D |
ab 132,00 €
Rebeccamycin
Artikelnummer: BVT-0139-C250
Antibiotic, Weak topoisomerase I (Topo I) inhibitor, Structurally similar to staurosporine, Does not show any inhibitory activity against protein kinases, Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells). Isolated from...
| Schlagworte: | NSC 359079, BRN 4732638 |
| Anwendung: | Topoisomerase I (Topo I) inhibitor |
| CAS | 93908-02-2 |
| MW: | 570,4 D |
ab 100,00 €
Meglumine
Artikelnummer: AG-CN2-0413-G005
White to off-white crystalline powder. Soluble in DMSO or water. Slightly soluble in ethanol. Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances, Counter ion used to replace sodium. It is impermeable towards cell...
| Schlagworte: | N-Methyl-D-glucamine, NSC52907, NSC7391, 1-Deoxy-1-methylaminosorbitol |
| Anwendung: | Excipient, Counter ion |
| CAS | 6284-40-8 |
| MW: | 195,2 D |
ab 28,00 €
COVID-19 Forschung
Tofacitinib
Artikelnummer: AG-CR1-3625-M005
Off-white to pale yellow solid. Soluble in DMSO or ethanol. Potent cell permeable JAK3 inhibitor (IC50 = 1nM). Shows also JAK-1 inhibitory activity, Immunosuppressive and anti-inflammatory agent, Inhibits signaling through heterodimeric receptors associated with JAK3, JAK1, or both of them, with functional...
| Schlagworte: | CP-690550, Xeljanz, Tasocitinib |
| Anwendung: | Cell-permeable JAK3 inhibitor |
| CAS | 477600-75-2 |
| MW: | 312,4 D |
ab 77,00 €