Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
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TACI (Human): Fc (human) (rec) Mulitpack
Artikelnummer: AG-40B-0079-3050
B-cell activating factor belonging to the TNF family receptor (BAFF-R), B-cell maturation antigen (BCMA), and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) play critical functions in promoting B-cell survival by engaging the ligands a proliferation-inducing ligand (APRIL)...
| Schlagworte: | CD267, TACI, TNFRSF13B, Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B |
| Anwendung: | ELISA, WB |
| Exprimiert in: | HEK 293 cells |
| Ursprungsart: | human, mouse |
| MW: | 46 kD |
ab 314,00 €
BCMA (human):Fc (human, rec.)
Artikelnummer: AG-40B-0080-3050
(3 x 50µg). The extracellular domain of human BCMA (amino acids 2-54) is fused at the C-terminus to the Fc portion of human IgG1. Blocks the binding of BAFF and APRIL to their receptors BCMA and TACI, inhibiting BAFF- and APRIL-mediated B cell activation. Lyophilized. Contains PBS. BCMA is a receptor for BAFF and...
| Schlagworte: | B Cell Maturation Protein, CD269, TNFRSF17 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human, mouse |
| MW: | 40 kD |
ab 275,00 €
Fas (human):Fc (human, rec.)
Artikelnummer: AG-40B-0082-3050
(3 x 50µg). The Fc portion of human IgG1 is fused to the C-terminus of human Fas (amino acids 26-170). Lyophilized. Contains PBS. Binds human and mouse FasL. FasL is a cytokine that binds to Fas/ TNFRSF6, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis...
| Schlagworte: | Tumor Necrosis Factor Receptor Superfamily Member 6,TNFRSF6, Apo-1 Antigen, CD95 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | human, mouse |
| MW: | 47 kD |
ab 286,00 €
IL-1beta (mouse, rec.) (untagged) (3 x 10 µg)
Artikelnummer: AG-40B-0086-3010
Mouse IL-1beta (amino acids 118-269) is untagged. IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B cell maturation and proliferation and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the...
| Anwendung: | Bioassays |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 17 kD |
ab 242,00 €
IGFL (mouse) (rec.)
Artikelnummer: AG-40B-0091-C010
Mouse IGFL (aa 25-140) is fused at the N-terminus to a Flag(R)-tag. Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or...
| Schlagworte: | Insulin Growth Factor-like Family Member, Gm580, Igfl3, mIgfl |
| Anwendung: | Biochemical studies |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 12 kD |
385,00 €
RANK (mouse):Fc (human) (rec.)
Artikelnummer: AG-40B-0092-3050
Mouse RANK (aa 29-213) is fused at the C-terminus to the Fc portion of human IgG1. RANK (TRANCE-R, CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
| Schlagworte: | TNFRSF11A, ODFR, Osteoclast Differentiation Factor Receptor, CD266 |
| Anwendung: | RANKL binding studies |
| Exprimiert in: | Human cells |
| Ursprungsart: | human, mouse |
| MW: | 55 kD |
ab 275,00 €
Interleukin-36 gamma (IL-36gamma), (mouse, rec.), untagged
Artikelnummer: AG-40B-0100-C010
IL-36gamma (mouse) (aa 13-183) is untagged. Induces secretion of IL-6 in BMDCs. IL-36alpha (IL-1F6), IL-36beta(IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12,...
| Schlagworte: | Il1f9, Il36g, IL-1F9, Interleukin-36 gamma, Interleukin-1 family member 9 |
| Anwendung: | IL-6 secretion induction |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 17 kD |
215,00 €
Periostin (human) (rec.)
Artikelnummer: AG-40B-0104-3010
Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both...
| Schlagworte: | PN, OSF2, POSTN, OSF-2, Periostin, Osteoblast-specific factor 2 |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
| MW: | ~75 kD |
ab 171,00 €
CD40L (rat) (multimeric) (rec.)
Artikelnummer: AG-40B-0107-3010
(3 x 10 µg). Rat CD40L (amino acids 115-260) is fused at the N-terminus to mouse ACRP30headless (amino acids 18-111) and a FLAG(R)-tag. Induces B cells activation (as demonstrated by dose-dependent upregulation of CD86). Lyophilized. Contains PBS. MultimericCD40L is a high activity construct in which two trimeric...
| Schlagworte: | MegaCD40L(TM), Soluble (rat, rec.), ACRP30headless:CD40L, ACRP30headless:CD154, ACRP30headless:TNFSF5, ADIPOQ-CD40L |
| Anwendung: | Bioassays |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human, mouse, rat |
ab 363,00 €
IL-6 (mouse):Fc (human) (rec.)
Artikelnummer: AG-40B-0108-3010
The extracellular domain of mouse IL-6 (aa 25-211) is fused at the C-terminus to the Fc portion of human IgG2. Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is...
| Schlagworte: | Interleukin-6, B Cell Hybridoma Growth Factor, Interleukin HP-1 |
| Anwendung: | Bioassays |
| Exprimiert in: | Human cells |
| Ursprungsart: | mouse |
| MW: | 50 kD |
ab 94,00 €
Notch1 (mouse): Fc (human) (rec.), (3x 50µg)
Artikelnummer: AG-40B-0109-3050
The extracellular domain of mouse Notch1 (aa 19-488) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1.
| Schlagworte: | Notch1, NOTCH-1, Notch ortholog 1, translocation-associated, TAN1, translocation-associated notch protein 1, hN1. |
| Exprimiert in: | CHO cells |
| Ursprungsart: | mouse |
| MW: | 85 kD |
ab 209,00 €
EDAR (human):Fc (human) (rec.)
Artikelnummer: AG-40B-0116-3050
The extracellular domain of human EDAR (aa 27-183) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. The TNF family ligand ectodysplasin A (EDA) and its receptor EDAR are required for proper development of skin appendages such as hair, teeth and eccrine sweat glands. Loss of...
| Schlagworte: | DL, EDAR, EDA-A1 receptor, Downless homolog, Ectodysplasin-A receptor, Ectodermal dysplasia receptor, Anhidrotic... |
| Anwendung: | EDA-A1 activity inhibitor |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human, mouse |
| MW: | 50 kD |
ab 286,00 €