Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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COVID-19 Forschung
Anti-ACE2 (human), clone AC18F
Artikelnummer: AG-20A-0032-C050
Recognizes human ACE2. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional...
| Schlagworte: | SARS Receptor, Angiotensin-converting Enzyme 2, ACEH |
| Anwendung: | ELISA, FC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 220,00 €
Vaspin (human) ELISA Kit
Artikelnummer: AG-45A-0017YEK-KI01
Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Culture Supernatant, Plasma, Serum. Sensitivity: 12pg/ml. Range: 0.016 to 1ng/ml. Vaspin (Visceral adipose tissue-derived serpin, Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated...
| Schlagworte: | OL-64, Vaspin, SERPINA12, Serpin A12, Visceral adipose-specific serpin, Visceral adipose tissue-derived serine protease... |
| Anwendung: | ELISA |
ab 660,00 €
Etoposide
Artikelnummer: AG-CR1-3572-M025
Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a...
| Schlagworte: | VP-16-213, NSC 141540 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Semisynthetic |
| CAS | 33419-42-0 |
| MW: | 588,6 D |
ab 33,00 €
Prostaglandin E2
Artikelnummer: AG-CL1-0001-M005
White solid. Soluble in ethanol (50 mg/ml), DMSO (50 mg/ml) or DMF (100 mg/ml). Sparingly soluble in PBS, pH 7.2 (5mg/ml). One of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme and acts on four kinds of receptor subtypes (EP1, EP2, EP3 and...
| Schlagworte: | PGE2, Dinoprostone, 9-Oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, Prostin E2, Prepidil, NSC165560,... |
| CAS | 363-24-6 |
| MW: | 352,5 D |
ab 33,00 €
Genistein
Artikelnummer: AG-CN2-0427-M010
White to off-white solid. Soluble in DMSO, slightly soluble in ethanol. Insoluble in water. Cell-permeable, reversible, substrate competitive tyrosine kinase inhibitor (including EGFR phosphorylation), implicated in almost all cell growth and proliferation signal cascades, Inhibitor of mammalian DNA topoisomerase...
| Schlagworte: | NSC 36586, Baichanin A, Differenol A, 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 446-72-0 |
| MW: | 270,2 D |
ab 28,00 €
Cucurbitacin E
Artikelnummer: AG-CN2-0474-M001
Off-white powder. Soluble in DMSO. Potent actin depolymerization inhibitor. Shown to have a different mechanism of action compared to jasplakinolide (Prod. No. AG-CN2-0037), binding to a different site, Binds specifically to filamentous actin (F-actin) forming a covalent bond at residue Cys257, stabilizing F-actin...
| Schlagworte: | Cuc E, alpha-Elaterin, alpha-Elaterine, NSC106399, BRN2343323 |
| Anwendung: | Actin depolymerization inhibitor |
| CAS | 18444-66-1 |
| MW: | 556,7 D |
ab 39,00 €
Suc-Leu-Leu-Val-Tyr-AMC
Artikelnummer: AG-CP3-0016-M005
Solid lyophilized powder. Soluble in DMSO. Fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome, calpains and other chymotrypsin-like proteases, Extinction: 380nm. Emission: 460 nm, This substrate is useful for inhibitor screening and kinetic analysis.
| Schlagworte: | Suc-LLVY-AMC, Proteasome Substrate, Calpain Substrate |
| Anwendung: | Fluorogenic proteasome substrate |
| CAS | 94367-21-2 |
| MW: | 763,9 D |
ab 39,00 €
Antipain . dihydrochloride
Artikelnummer: AG-CP3-7002-M005
White to off-white solid. Soluble in water, ethanol, methanol, DMSO or acetonitrile. Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D, Similar activity spectrum comparable to leupeptin...
| Schlagworte: | [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl |
| Anwendung: | Papain / trypsin / trypsin-like serine protease / cathepsin A & B & D inhibitor |
| CAS | 37682-72-7 |
| MW: | 677,6 D |
ab 44,00 €
Nocodazole
Artikelnummer: AG-CR1-0019-M005
Microtubule inhibitor, Antitumor compound, Mitosis inhibitor, Arrests the cell cycle at G2/M phase, Promotes tubulin depolymerization, Induces fragmentation of the Golgi complex, Inhibits the T cell antigen receptor, Stimulates the intrinsic GTPase activity of tubulin, Activates the JNK/SAPK signaling pathway,...
| Schlagworte: | Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate |
| Anwendung: | Microtubule inhibitor, Mitosis inhibitor |
| CAS | 31430-18-9 |
| MW: | 301,3 D |
ab 39,00 €
R-848
Artikelnummer: AG-CR1-3582-M005
Synthetic. Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates...
| Schlagworte: | Resiquimod, S 28463, R848 |
| Anwendung: | TLR7 ligand |
| CAS | 144875-48-9 |
| MW: | 314,4 D |
ab 55,00 €
Gentamicin sulfate (USP Grade)
Artikelnummer: AG-CN2-0066-G001
Aminoglycoside antibiotic - Protein synthesis inhibitor. Causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site - Antibacterial against Gram-negative aerobic bacteria, Gram-positive bacteria and mycoplasmas - Used as a...
| Schlagworte: | Apogen, Garamycin, Gentiomycin C, Refobacin, NSC-82261 |
| Anwendung: | Antibiotic |
| Wirt: | Micromonospora sp |
| CAS | 1405-41-0 |
ab 44,00 €
Stigmasterol
Artikelnummer: AG-CN2-0412-G001
White to off-white solid. Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water. Anti-hypercholestrolemic compound, Anti-inflammatory and immune-modulating effects, Anticancer compound. Chemopreventive, Cytostatic. Cell growth inhibitor, Antimutagenic, Potent in vitro antagonist of FXR (farnesoid...
| Schlagworte: | Stigmasterin, Phytosterol, beta-Stigmasterol, Serposterol, Wulzen anti-stiffness Factor, NSC8095 |
| Anwendung: | Chemopreventive compound |
| CAS | 83-48-7 |
| MW: | 412,7 D |
ab 44,00 €