Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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Suramin, hexasodium salt
Artikelnummer: AG-CR1-3575-M050
Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-specific growth factors inhibitor (including PDGF, EGF, aFGF and bFGF). TGF-beta1...
| Schlagworte: | Germanin, NSC 34936, SK 24728 |
| Anwendung: | ATPase Inhibitor |
| Wirt: | Synthetic |
| CAS | 129-46-4 |
| MW: | 1429,1 D |
ab 77,00 €
(+)-Brefeldin A
Artikelnummer: AG-CN2-0018-M005
Isolated from Penicillium janthinellum. Protein transport from ER to Golgi inhibitor. ADP-ribosylation factor (Arf) inhibitor. Cytotoxic. Antibiotic. Antiviral. Apoptosis inducer. Antitumor compound. Intracellular collagen degradation inhibitor.
| Schlagworte: | Ascotoxin, Decumbin, Cyanein, Synergisidin |
| Anwendung: | ADP-ribosylation factor (Arf) inhibitor, Apoptosis inducer |
| CAS | 20350-15-6 |
| MW: | 280,4 D |
ab 44,00 €
Puromycin-2HCl
Artikelnummer: AG-CN2-0078-M100
Aminonucleoside antibiotic - Protein synthesis inhibitor. Disrupts peptide transfer on ribosomes (acting as an acyl-tRNA analog) causing premature chain termination during translation. Translational inhibitor in prokaryotic and eukaryotic cells in both in vitro and in vivo systems - Inhibits the transport of...
| Schlagworte: | CL16,536, NSC 3055, Stylomycin |
| Anwendung: | Antibiotic |
| Wirt: | Bacillus polymyxa |
| CAS | 58-58-2 |
ab 44,00 €
SAG . dihydrochloride (water soluble)
Artikelnummer: AG-CR1-3585-M005
Soluble in water or DMSO. Cell permeable Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Induces Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo. Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations....
| Schlagworte: | N-Methyl-N?-(3-pyridinylbenzyl)-N?-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane . 2HCl |
| Anwendung: | SMO agonist |
| CAS | 364590-63-6 |
| MW: | 581 D |
ab 39,00 €
Anti-IL-33 (human), clone IL33305B
Artikelnummer: AG-20A-0041-C100
Recognizes human IL-33. Does not cross-react with mouse IL-33. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be...
| Schlagworte: | Interleukin-33, IL-1F11, NF-HEV |
| Anwendung: | ELISA, FA (Blocking), IHC, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 253,00 €
H-89 . dihydrochloride
Artikelnummer: AG-CR1-0002-M005
Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) inhibitor, Apoptosis enhancer, Tool to study protein crystal...
| Schlagworte: | N-[2-(p-Bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide . 2HCl |
| Anwendung: | PKA/PKG inhibitor, PKC inhibitor |
| CAS | 127243-85-0 |
| MW: | 519.3 D |
ab 28,00 €
BAY 11-7082
Artikelnummer: AG-CR1-0013-M010
IkappaBalpha kinase inhibitor, NF-kappaB inhibitor, Potential anti-inflammatory agent, Apoptosis inducer, Inhibits the release of proinflammatory cytokines, Inflammasome inhibitor Inhibits platelet aggregation.
| Schlagworte: | (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile |
| Anwendung: | NFkappaB inhibitor |
| CAS | 19542-67-7 |
| MW: | 207,3 D |
ab 66,00 €
Averufin
Artikelnummer: AG-CN2-0527-M001
Mycotoxin. Isolated from fungus Aspergillus versicolor. Biosynthetic precursor of aflatoxins. Antibiotic. Shows moderate antibacterial activity against Gram-positive bacteria. Oxidative phosphorylation (OXPHOS) inhibitor. Inhibits succinate cytochrome c reductase complex (III) of the respiratory chain in...
| Schlagworte: | (2S,6S)-7,9,11-Trihydroxy-2-methyl-3,4,5,6-tetrahydro-2H-2,6-epoxyanthra[2,3-b]oxocine-8,13-dione, BRN1299991 |
| Anwendung: | Mycotoxin, Aflatoxin biosynthesis intermediate, Oxidative phosphorylation (OXPHOS) inhibitor |
| CAS | 14016-29-6 |
| MW: | 368.3 D |
154,00 €
COVID-19 Forschung
Chloroquine . diphosphate
Artikelnummer: AG-CR1-3721-G001
Soluble in water (20mg/ml). Chloroquine is a commonly used antimalarial drug, more toxic than its derivative hydroxychloroquine (Prod. No. AG-CR1-3720). Chloroquine has anti-inflammatory, immunomodulating, anti-infective, antiviral, antithrombotic and metabolic effects. It has anticancer properties, related to their...
| Schlagworte: | N4-(7-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine diphosphate, DL-Chloroquine, NSC 14050 |
| Anwendung: | Antimalarial, amebicide |
| CAS | 50-63-5 |
| MW: | 515.86 D |
ab 22,00 €
Anti-Caspase-1 (p20) (human) , clone Bally-1, Biotin...
Artikelnummer: AG-20B-0048B-C100
Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1...
| Schlagworte: | Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE |
| Anwendung: | WB |
| Wirt: | mouse |
| Spezies-Reaktivität: | human |
506,00 €
Anti-Angiopoietin-2 (human), mAb (rec.) (blocking)...
Artikelnummer: AG-27B-0016PF-C100
Recognizes human angiopoietin-2. Recognizes weakly mouse angiopoietin-2 (~10 x less efficiently by ELISA). Does not detect human angiopoietin-1. Anti-Angiopoietin-2 (human), mAb (rec.) (blocking) (Angy-2-1) is composed of human variable regions (VH and VL) (?-chain) of immunoglobulin fused to the mouse lgG2b Fc domain.
| Schlagworte: | Anti-ANG-2, Anti-ANGPT2, Anti-Angiopoietin-2 |
| Anwendung: | ELISA, FA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 402,00 €
COVID-19 Forschung
Anti-ACE2 (human), clone AC18F
Artikelnummer: AG-20A-0032-C050
Recognizes human ACE2. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional...
| Schlagworte: | SARS Receptor, Angiotensin-converting Enzyme 2, ACEH |
| Anwendung: | ELISA, FC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 220,00 €