Produkte von AdipoGen Life Sciences
AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler*innen entwickeln dort neue Produkte für den Life Science-Markt in den Bereichen Krebs, Immunologie, Entzündung (der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.
Mehr Informationen unter: www.adipogen.com
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H-D-Val-Leu-Lys-pNA . 2HCl
Artikelnummer: AG-CP3-0042-M025
D-Val-Leu-Lys-p-nitroanilide is a selective colorimetric substrate for plasmin used to determine the formation of plasmin from plasminogen in amidolytic activity assays and plasminogen activating assays. Plasmin is a plasma serine protease whose main role is to dissolve fibrin blood clots. After cleavage by plasmin...
| Anwendung: | Photometric plasmin substrate |
| CAS | 62354-43-2 |
| MW: | 551.5 D |
ab 66,00 €
Anti-Cardif (human), clone Adri-1
Artikelnummer: AG-20B-0004-C100
Recognizes human Cardif. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I (retinoic acid-inducible gene I, Ddx58) and MDA5 (melanoma differentiation-associated gene 5, also known as Ifih1 or Helicard) are proteins that sense viral replication intermediates, such as double-stranded RNA and...
| Schlagworte: | CARD Adapter Inducing Interferon-beta, IPS-1, Interferon-beta Promoter Stimulator Protein 1, MAVS, Mitochondrial Antiviral... |
| Anwendung: | ICC, IHC, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
407,00 €
Anti-NLRP3/NALP3 (mouse), clone Cryo-1
Artikelnummer: AG-20B-0006-C100
Recognizes mouse NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like...
| Schlagworte: | NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
462,00 €
Anti-Caspase-4/11 (p20), clone Flamy-1
Artikelnummer: AG-20B-0060-C100
Recognizes endogenous full-length protein and activated (p20) fragment of mouse and human caspase-4/11
| Schlagworte: | Anti-CASP-4, Anti-CASP-11, Anti-Protease ICH-3, Anti-Ich3, EC=3.4.22.64 |
| Anwendung: | WB, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
385,00 €
Anti-DNER (human)
Artikelnummer: AG-25A-0102-C100
Recognizes human DNER (ED). Detects a band of about 98kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
| Schlagworte: | BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
182,00 €
Anti-NALP1/NLRP1 (human) (AL176)
Artikelnummer: AG-25B-0005-C100
Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Liquid. Neat serum containing 0.02% sodium azide. NALP1/NLRP1 is able to form cytoplasmic structures termed death effector filaments. It enhances and stimulates apoptosis through activation of different caspase cascades. It is involved in the...
| Schlagworte: | NACHT-, LRR- and PYD-containing protein 1, Caspase recruitment domain-containing protein 7, Death effector... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
374,00 €
Fc (human):FasL, Soluble (human) (rec.)
Artikelnummer: AG-40B-0132-3010
3 x 10 µg. Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates...
| Schlagworte: | SPA, APL, FasL, APTL, CD178, FASLG, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95 ligand, Fas antigen ligand, Soluble... |
| Anwendung: | FasL aggregation stimulator |
| Exprimiert in: | Human cells |
| Ursprungsart: | human, mouse |
| MW: | 50 kD |
ab 319,00 €
Jak/Src Inhibitor 1 . hydrochloride
Artikelnummer: AG-CR1-3647-M001
Yellow solid. Soluble in DMSO. Anticancer compound. Potent antiproliferative agent in vitro and in vivo, Combined inhibitor of pSTAT3 proteins such as JAK, SRC, ABL and class III/V receptor tyrosine kinases (RTK), including FLT3, c-KIT, CSF1-R, PDGFRs and VEGFRs, in nanomolar range.
| Schlagworte: | Debio 0617B . HCl,... |
| Anwendung: | Anticancer compound |
| CAS | 1332329-27-7 |
| MW: | 618,5 D |
143,00 €
Monosodium urate (crystals)
Artikelnummer: AG-CR1-3950-2002
NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.
| Schlagworte: | MSU (crystals), Uric acid (crystals) |
| Anwendung: | NLRP3/NALP3 inflammasome activator |
| Wirt: | Synthetic |
| CAS | 1198-77-2 |
| MW: | 167,1 D |
ab 94,00 €
Fumitremorgin C
Artikelnummer: BVT-0189-M001
Mycotoxin, Tremorgenic, Potent and specific inhibitor of the breast cancer resistance protein (BCRP, ABCG2), Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Isolated from Aspergillus fumigatus.
| Schlagworte: | Tryptoquivaline |
| Anwendung: | Breast cancer resistance protein inhibitor |
| CAS | 118974-02-0 |
| MW: | 379,5 D |
ab 90,00 €
Dimethylsulfoniopropionate . HCl
Artikelnummer: BVT-0468-M100
White needles. Stable salt form. Soluble in DMSO, methanol or water. Naturally occurring organosulfur compound, Osmolyte, osmoprotectant, Antioxidant, Cryoprotectant, Neuroprotective agent. Neuritogenic, Acts against immune-deficient diseases (e.g. cancer), Important in geochemistry, ecology and algal/plant...
| Schlagworte: | 3-Dimethylsulfoniopropionate, Dimethylpropiothetin (DMPT), (2-Carboxyethyl)dimethylsulfonium betaine |
| Anwendung: | Antioxidant, Cryoprotectant, Neuroprotective agent |
| CAS | 4337-33-1 |
| MW: | 170,7 D |
135,00 €
Raptinal
Artikelnummer: AG-CR1-2902-M005
Beige solid. Soluble in DMSO. Rapid apoptosis inducer that initiates intrinsic pathway caspase-dependent apoptosis within minutes in multiple cell lines and in vivo systems. Exerts anticancer activity in vivo, likely through the induction of apoptosis, Induces cell death against various cancer and non-cancerous cell...
| Schlagworte: | [9,9'-Bi-9H-fluorene]-9,9'-dicarboxaldehyde, NSC 610970 |
| Anwendung: | Rapid apoptosis inducer |
| CAS | 1176-09-6 |
| MW: | 386,4 D |
ab 33,00 €