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Sancycline
Sancycline

Artikelnummer: Cay23100-5

Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Cay-14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from...
Schlagworte: 6-Demethyl-6-deoxytetracycline, GS 2147,...
Anwendung: Antibacterial, Tetracycline antibiotic, Protein biosynthesis inhibitor, 30S subunit inhibitor
CAS 808-26-4
MW: 414.4 D
ab 43,00 €
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Chlortetracycline
Chlortetracycline

Artikelnummer: Cay23302-5

Chlortetracycline is a broad-spectrum antibiotic originally isolated from S. aureofaciens. It inhibits growth of both Gram-positive and Gram-negative bacteria at a range of 0.1-100 µg/ml against A. aerogenes, D. pneumoniae, E. coli, K. pneumoniae, P. morganii, and several species of Haemophilus, Neisseria,...
Schlagworte: 7-Chlortetracycline,...
Anwendung: Broad-spectrum antibiotic, Protein biosynthesis inhibitor
CAS 57-62-5
MW: 478.9 D
ab 237,00 €
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Rolitetracycline
Rolitetracycline

Artikelnummer: Cay23479-5

Rolitetracycline is a tetracycline antibiotic with bacteriostatic activity at low concentrations (7.8 µg/ml) and bactericidal activity at high concentrations (15.6 µg/ml) against E. coli. It has additive and synergistic effects with penicillin and cephalothin, respectively, in vitro against 34 E. coli and S. aureus...
Schlagworte: Pyrrolidinylmethyltetracycline, SQ 15,659,...
Anwendung: Antibacterial, Protein biosynthesis inhibitor
CAS 751-97-3
MW: 527.6 D
ab 163,00 €
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Doxycycline (hyclate)
Doxycycline (hyclate)

Artikelnummer: Cay14422-1

Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix metalloproteinase-8 (MMP-8) and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, when used at a concentration of 30 µM. It can be...
Schlagworte: (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-...
Anwendung: Antibiotic
CAS 24390-14-5
MW: 1025.9 D
ab 43,00 €
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Anhydrochlortetracycline (hydrochloride)
Anhydrochlortetracycline (hydrochloride)

Artikelnummer: Cay19941-1

Anhydrochlortetracycline is an impurity of the tetracycline antibiotic chlortetracycline formed by acid degradation. It is a poor inhibitor of protein synthesis and has minor antimicrobial activity against various strains of actinomycetes.Formal Name:...
Schlagworte: (4S,4aS,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthac...
Anwendung: Chlortetracycline impurity
CAS 65490-24-6
MW: 497.3 D
ab 109,00 €
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Tetracycline (hydrochloride)
Tetracycline (hydrochloride)

Artikelnummer: Cay14328-10

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems....
Schlagworte: (4S,4aS,5aS,6S,12aS)-...
Anwendung: Antibiotic
CAS 64-75-5
MW: 480.9 D
ab 48,00 €
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Minocycline (hydrochloride hydrate)
Minocycline (hydrochloride hydrate)

Artikelnummer: Cay14454-25

Minocycline is a broad-spectrum tetracycline antibiotic. It is active against E. faecium in vitro (MIC = 16 mg/L). Minocycline (20 mg/kg every 12 hours) reduces the number of bacteria in the lung in a mouse model of multidrug resistant A. baumannii-induced pneumonia. It reduces spinal cord lesion size and improves...
Schlagworte: NSC 141993,...
Anwendung: Antibiotic
MW: 493.9 D
ab 43,00 €
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Oxytetracycline
Oxytetracycline

Artikelnummer: Cay18076-10

Oxytetracycline is a broad-spectrum tetracycline antibiotic that inhibits protein synthesis in both Gram-positive and Gram-negative bacteria. The features of its biosynthesis often serve as a representative example for understanding the synthesis of other type II polyketides. Oxytetracycline is also used to examine...
Schlagworte: NSC 9169, Terramycin,...
Anwendung: Antibiotic, Protein synthesis inhibitor
CAS 79-57-2
MW: 460.4 D
ab 43,00 €
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Epitetracycline (hydrochloride)
Epitetracycline (hydrochloride)

Artikelnummer: Cay19470-10

Epitetracycline is an epimer of the antibiotic tetracycline (Cay-14328). Epimers of tetracycline form without catalysis and are considered degradation products. Epitetracycline has decreased activity as an antibiotic or a Tet repressor effector but may have stronger toxic effects in animals.Formal Name:...
Schlagworte: 4-epi-Tetracycline, Quatrimycin,...
Anwendung: Tetracycline degradation product
CAS 23313-80-6
MW: 480.9 D
ab 77,00 €
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Methacycline (hydrochloride)
Methacycline (hydrochloride)

Artikelnummer: Cay21338-1

Methacycline is a tetracycline-class antibiotic that is active against a wide range of Gram-positive and Gram-negative organisms. It is readily absorbed from the gastrointestinal tract and reaches a maximum concentration at about the fourth hour, declining to a negligible amount in about 24 hours. It is more active...
Schlagworte: 6-methylene Oxytetracycline, Rondomycin,...
Anwendung: Antibiotic, Antibacterial, Protein biosynthesis inhibitor
CAS 3963-95-9
MW: 478.9 D
ab 43,00 €
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Isochlortetracycline
Isochlortetracycline

Artikelnummer: Cay22125-1

Isochlortetracycline is an inactive alkaline degradation product of the broad-spectrum antibiotic chlortetracycline. This molecule appears to be a product of in vivo chlortetracycline metabolism with epimerization rates exceeding >50%, and high levels can be detected in the yolks of eggs from chickens exposed to...
Schlagworte: 7-Chloroisotetracycline, Isoaureomycin,...
Anwendung: Chlortetracycline metabolite, Reference standard
CAS 514-53-4
MW: 478.9 D
ab 77,00 €
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4-epi-Chlortetracycline (hydrochloride)
4-epi-Chlortetracycline (hydrochloride)

Artikelnummer: Cay16663-500

Chlortetracycline is an analog of tetracycline (Cay-14328), a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects of the innate immune response. 4-epi-Chlortetracycline is an epimer of...
Schlagworte: 7-chloro-2-Naphthacenecarboxamide,...
Anwendung: Antibiotic, Innate immune response suppressor
CAS 101342-45-4
MW: 515.3 D
ab 125,00 €
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Demeclocycline (hydrochloride)
Demeclocycline (hydrochloride)

Artikelnummer: Cay21759-500

Demeclocycline is a broad-spectrum tetracycline antibiotic produced by S. aureofaciens. It has antimicrobial activity against ~3,200 pathogenic Gram-positive and Gram-negative bacteria in vitro that is 2-fold greater than that of tetracycline (Cay-14328). The bactericidal action of demeclocycline is comparable to...
Schlagworte: Demethylchlortetracycline, Demethyltetracycline,...
Anwendung: Antibiotic
CAS 64-73-3
MW: 501.3 D
ab 115,00 €
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Meclocycline
Meclocycline

Artikelnummer: Cay27940-5

Meclocycline is a tetracycline antibiotic. It has broad antimicrobial activity in vitro, including growth inhibition of the bacterium S. epidermidis when used at a concentration of 0.8 µg/ml. Meclocycline inhibits lactate dehydrogenase (LDH) release and cell toxicity induced by expression of htt-N63-148Q, a mutant...
Schlagworte: GS-2989, NSC 78502,...
Anwendung: Antibacterial, protein biosynthesis inhibitor, tetracycline antibiotic
CAS 2013-58-3
MW: 476.9 D
ab 212,00 €
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Epioxytetracycline
Epioxytetracycline

Artikelnummer: Cay27987-1

Epioxytetracycline is a degradation product of the antibiotic oxytetracycline (Cay-18076). It has been found in swine manure compost and wastewater and is considered a pollutant.Formal Name:...
Schlagworte: 4-epi-Oxytetracycline,...
Anwendung: Oxytetracycline degradation product
CAS 14206-58-7
MW: 460.4 D
ab 163,00 €
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beta-Apooxytetracycline
beta-Apooxytetracycline

Artikelnummer: Cay27099-500

beta-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. beta-Apooxytetracycline is a degradation product formed from oxytetracycline (Cay-18076) via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge...
Schlagworte: beta-Apo-Oxytetracycline, beta-Apoterramycin,...
Anwendung: Potential impurity, Degradation product
CAS 18751-99-0
MW: 442.4 D
ab 54,00 €
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Epianhydrotetracycline (hydrochloride)
Epianhydrotetracycline (hydrochloride)

Artikelnummer: Cay27954-1

Epianhydrotetracycline (EATC) is a degradation product of the antibiotic tetracycline (Cay-14328). EATC is active against Pseudomonas, Agrobacterium, Moraxella, Bacillus, and E. coli (MIC50s = 0.75-16 mg/L).Formal Name:...
Schlagworte: EATC,...
Anwendung: Tetracycline degradation product, Antibiotic
CAS 4465-65-0
MW: 462.9 D
ab 43,00 €
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Sancycline (hydrochloride)
Sancycline (hydrochloride)

Artikelnummer: Cay28118-25

Sancycline is a semisynthetic tetracycline antibiotic that is more active than tetracycline (Cay-14328) against 339 strains of anaerobic bacteria (average MIC90s = 1 and 32 µg/ml, respectively). Sancycline is active against tetracycline-resistant E. coli, S. aureus, and E. faecalis strains with MICs ranging from...
Schlagworte: 6-Demethyl-6-deoxytetracycline, NSC 51812,...
Anwendung: Antibacterial tetracycline antibiotic
CAS 6625-20-3
MW: 450.9 D
ab 205,00 €
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Doxycycline-d3 (hyclate)
Doxycycline-d3 (hyclate)

Artikelnummer: Cay28528-1

Doxycycline-d3 is intended for use as an internal standard for the quantification of doxycycline (Cay-14422) by GC- or LC-MS. Doxycycline is a broad-spectrum tetracycline antibiotic. It inhibits bacterial protein synthesis by binding to ribosomes. Doxycycline also selectively inhibits human matrix...
Schlagworte: (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-(6-methyl-d)-1,11-diox...
Anwendung: GC-MS, LC-MS, Internal standard, Quantification, Antibacterial, Protein biosynthesis inhibitor
MW: 894.9 D
432,00 €
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