Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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PIKfyve-IN-1

Artikelnummer: TGM-T60980-100mg

Description: PIKfyve-IN-1 is a cell-active and highly potent chemical probe that can be used for the PIKfyve research in virology. PIKfyve-IN-1 inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) (IC 50 = 6.9 nM)[1]. Target: Others

MW:

331.41 D

ab 1.440,00 €

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TRPC4/5-IN-1

Artikelnummer: TGM-T60981-100mg

Description: TRPC4/5-IN-1 can be used for the research of skin inflammatory diseases and proteinuric kidney diseases. TRPC4/5-IN-1 is a potent inhibitor of TRP channel 5/4 (TRPC5/4) with IC50 values of 0.54 µM and 2.06 µM, respectively. [1]. Target: Others

MW:

331.41 D

ab 1.440,00 €

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KCa2 channel modulator 2

Artikelnummer: TGM-T60986-100mg

Description: KCa2 channel modulator 2 (compound 2q) is an effective, subtype-selective K/Ca 2 channel positive modulator with similar potency on the human K Ca 2.3 channel and rat K Ca 2.2a subtypes, exhibiting EC50 values of 0.60 µM and 0.64 µM, respectively [1]. Target: Others

MW:

331.78 D

ab 1.440,00 €

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FTO-IN-6

Artikelnummer: TGM-T60994-100mg

Description: FTO-IN-6 is a selective inhibitor of the fat mass and obesity-associated protein (FTO). Target: Others

MW:

332.27 D

ab 1.440,00 €

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GL0388

Artikelnummer: TGM-T60997-100mg

Description: GL0388 is a Bax activator and leads to Bax insertion into mitochondrial membrane that induce Bax-mediated apoptosis. GL0388 inhibits tumor growth of breast cancer xenograft in vivo which also exhibits antiproliferative activities against a variety of cancer cells with IC50 values of 0.299-1.57 µM [1]....

MW:

332.37 D

ab 834,00 €

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AEP-IN-1

Artikelnummer: TGM-T61004-100mg

Description: APE-IN-1 can be used for the early diagnosis and drug research of Alzheimer's disease. APE-IN-1 is a potent Asparagine endopeptidase (AEP) inhibitor with IC 50 value of 89 nM [1]. Target: Others

MW:

333.43 D

ab 1.440,00 €

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CA IX-IN-1

Artikelnummer: TGM-T62387-100mg

Description: CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) with demonstrated antitumour effects. Target: Others

MW:

430.43 D

ab 1.440,00 €

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KB-5492 FA

Artikelnummer: TGM-T62396L-10mg

Description: KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS ??128-52-56-8. Target: Sigma receptor. Smiles: O=C(CN1CCN(CC1)CC2=CC(OC)=C(C(OC)=C2)OC)OC3=CC=C(C=C3)OC.[H]C(O)=O. References: Morimoto Y,et al. Effects of KB-5492, a new anti-ulcer agent, on ethanol- and acidified...

Schlagworte:	KB-5492 FA(113594-64-2 Free base)
MW:	476.52 D

ab 53,00 €

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KDM1/CDK1-IN-1

Artikelnummer: TGM-T62405-100mg

Description: KDM1/CDK1-IN-1 (compound 4) is a potent inhibitor of KDM1 (IC50: 0.096 µM) and CDK1 (IC50: 0.078 µM), blocking the cell cycle of HOP-92 cells in the G2/M phase and inducing apoptosis. It is highly cytotoxic to CCRF-CEM cells (IC50: 16.34 µM), HOP-92 cells (IC50: 3.45 µM), and Hep-G2 cells (IC50: 7.79...

MW:

431.47 D

ab 1.440,00 €

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AD012

Artikelnummer: TGM-T62831-100mg

Description: AD012 is a dual inhibitor of cACE/NEP that utilizes the previously reported C-domain selective ACE inhibitor lenopril-tryptophan synthesis, potentially offering potent anti-hypertensive and cardioprotective effects. Target: Others

MW:

456.53 D

ab 1.440,00 €

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Antitumor agent-54

Artikelnummer: TGM-T62835-100mg

Description: Antitumor agent-54 (Compound C11) is a 14-3-3eta protein inhibitor (KD: 35 µM). antitumor agent-54 inhibits several typical human hepatocellular carcinoma cell lines. antitumor agent-54 blocks the cell cycle in the G1-S phase and induces apoptosis, showing good metabolic stability. It exhibits good...

MW:

456.58 D

ab 1.440,00 €

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