Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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HER2-IN-11

Artikelnummer: TGM-T60896-100mg

Description: HER2-IN-11 is a psoralen derivative that induces apoptosis, exhibits light-activated cytotoxicity, and demonstrates anti-breast cancer activity [1]. Target: Others

MW:

325.27 D

ab 1.440,00 €

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HbF inducer-1

Artikelnummer: TGM-T60898-100mg

Description: HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable. Target: Others

MW:

325.36 D

ab 1.440,00 €

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IRAK4-IN-11

Artikelnummer: TGM-T60899-100mg

Description: IRAK4-IN-11 (compound 6) is a potent IRAK4 inhibitor with an IC50 of 0.008 µM, demonstrating cell pIRAK4 potencies with an IC50 of 0.19 µM [1]. Target: Others

MW:

325.37 D

ab 1.440,00 €

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Miaosporone A

Artikelnummer: TGM-T60906-100mg

Description: Miaosporone A is an angucyclic quinone which shows cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells. Miaosporone A has antibacterial activity against Mycobacterium tuberculosis and antimalarial activity against Plasmodium falciparum K1 with IC50 values of...

MW:

326.34 D

ab 1.440,00 €

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EGFR/HER2-IN-8

Artikelnummer: TGM-T60938-100mg

Description: EGFR/HER2-IN-8 (compound 34) is an inhibitor of EGFR, HER2, and DHFR with IC50 values of 0.45 µM, 0.244 µM, and 5.669 µM, respectively. It demonstrates anticancer activity against several cancer cell lines, exhibiting a high safety profile and selectivity indices, making it useful for cancer research...

MW:

328.39 D

ab 1.440,00 €

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ChE/Abeta1-42-IN-1

Artikelnummer: TGM-T60940-100mg

Description: ChE/Abeta1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Abeta1-42 with excellent BBB permeability, exhibiting IC50 values of 0.062 µM for AChE, 0.767 µM for BuChE, and 1.227 µM for Abeta1-42 aggregation. ChE/Abeta1-42-IN-1 is a potent multi-targeted anti-Alzheimer's disease agent...

MW:

328.41 D

ab 1.440,00 €

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LSD1-IN-15

Artikelnummer: TGM-T60941-100mg

Description: LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor that inhibits LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.149, 0.028, and 0.327 µM, respectively. LSD1-IN-15 induces cell growth arrest in LNCaP cells of prostate cancer, with an IC50 value of 9.9 µM [1]. Target: Others

MW:

328.41 D

ab 1.440,00 €

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MC2652

Artikelnummer: TGM-T60942-100mg

Description: MC2652 (compound 1a) is a potent LSD1 inhibitor with high inhibitory effects in MV4-11 and NB4 leukemia cells and exhibits antiproliferative activity against LNCaP prostate cancer cells [1]. Target: Others

MW:

328.41 D

ab 1.440,00 €

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Antitubercular agent-15

Artikelnummer: TGM-T60945-100mg

Description: Antitubercular agent-15 (Compound 5n) is an antitubercular agent with low cytotoxicity against pulmonary fibroblasts and macrophages. The MIC90 values against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152, and CF161 are 0.73, 7.69, 9.38, 18.80, 7.53, and 7.31 µg/mL, respectively [1]. Target: Others

MW:

328.47 D

ab 1.440,00 €

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Complex III-IN-2

Artikelnummer: TGM-T60949-100mg

Description: Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor with antifungal activity, exhibiting EC50 values of 29.31 mg/L against R. solani and 29.98 mg/L against Sclerotinia sclerotiorum [1]. Target: Others

MW:

328.86 D

ab 1.440,00 €

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Antitumor agent-50

Artikelnummer: TGM-T60975-100mg

Description: Antitumor agent-50 (compound 1a) is a thiazolidinone. Antitumor agent-50 is an effective antitumor agent that has the potential for the research of osteosarcoma (OS) [1]. Target: Others

MW:

331.36 D

ab 1.440,00 €

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COX-2-IN-7

Artikelnummer: TGM-T60978-100mg

Description: COX-2-IN-7 (compound 4a) is a potent and selective COX-2 inhibitor with greater selectivity than Celecoxib and an IC50 value of 6.585 µM. It exhibits good anti-inflammatory properties and low ulcerogenic activity in vivo[1]. Target: Others

MW:

331.41 D

ab 1.440,00 €

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