Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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BRD4 D1-IN-2

Artikelnummer: TGM-T64192-100mg

Description: BRD4 D1-IN-2 (compound 26) is a selective and potent inhibitor of BRD4 D1, exhibiting an IC50 value of less than 0.092 µM and a 15 nM affinity for BRD4 D1, with over 500-fold selectivity for BRD2 D1 and BRD4 D2. Target: Others

MW:

592.7 D

ab 1.440,00 €

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AKR1C3-IN-5

Artikelnummer: TGM-T64193-100mg

Description: AKR1C3-IN-5 (Compound 6e) is a potent inhibitor of AKR1C3, derived from drupanin, with significant activity against MCF-7 cells (IC50: 9.6 ± 3 µM, SI: 5.5). AKR1C3 enzymes are overexpressed in hormone-dependent prostate and breast tumors. Target: Others

MW:

592.72 D

ab 1.440,00 €

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Antibacterial agent 112

Artikelnummer: TGM-T64197-100mg

Description: Antibacterial agent 112 (compound 2) is a potent antibacterial agent with a minimum inhibitory concentration (MIC) of 1250 µM against B. subtilis, E. coli, E. faecalis, S. typhimurium, and S. aureus microorganisms. A3N19 is an HIV-1 antibody with antibacterial activity. Target: Others

MW:

593.59 D

ab 1.440,00 €

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4-Nitrophenyl dodecanoate

Artikelnummer: TGM-T64931-100mg

Description: 4-Nitrophenyl dodecanoate (p-Nitrophenyl laurate) is a substrate for lipase and can be used to assess lipase activity. Target: Others. Smiles: CCCCCCCCCC CC(=O)Oc1ccc(cc1)[N+]([O-])=O

MW:

321.41 D

ab 30,00 €

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Antibacterial agent 70

Artikelnummer: TGM-T64201-100mg

Description: Antibacterial Agent 70, a novel dihydropyrimidinone-imidazole hybrid antimicrobial agent, has a minimum inhibitory concentration (MIC) of 0.5 µg/ml. Target: Others

MW:

594.08 D

ab 1.440,00 €

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T-Type calcium channel inhibitor 2

Artikelnummer: TGM-T64203-100mg

Description: T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, specifically acting on Cav3.1 (alpha1G) with an IC50 of 31.0 µM, Cav3.2 (alpha1H) with an IC50 of 83.1 µM, and Cav3.3 (alpha1I) (alpha1H). T-Type calcium channel inhibitor 2 exhibited cytotoxicity...

MW:

594.78 D

ab 1.440,00 €

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FAK-IN-6

Artikelnummer: TGM-T64207-100mg

Description: FAK-IN-6 is a potent inhibitor of FAK (IC50: 1.415 nM) that exhibits anti-proliferative effects on certain cancer cell lines, and can be used to study pancreatic cancer. Target: Others

MW:

596.04 D

ab 1.440,00 €

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SM-433 hydrochloride

Artikelnummer: TGM-T64217-25mg

Description: SM-433 hydrochlorid is a Smac mimetic, an inhibitor of inhibitory apoptosis proteins (IAPs). SM-433 hydrochlorid is able to bind XIAP BIR3 protein with a potent IC50 <1 µM. Target: Others

MW:

598.18 D

ab 1.488,00 €

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Keap1-Nrf2-IN-1 TFA

Artikelnummer: TGM-T64218-100mg

Description: Keap1-Nrf2-IN-1 TFA (compound35) is a Keap1-Nrf2 protein-protein interaction inhibitor (IC50: 43 nM) that activates Nrf2-regulated cytoprotective responses and antagonizes acetaminophen-induced liver injury in both cellular and in vivo models. Target: Others

MW:

598.54 D

ab 1.440,00 €

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JAK2 JH2 binder-1

Artikelnummer: TGM-T64227-100mg

Description: JAK2 JH2 binder-1 is a potent and selective JAK2 JH2 binder (Ki: 37.1 nM). JAK2 JH2 binder-1 has the potential to be used in the study of various myeloproliferative neoplasms. Target: Others

MW:

599.62 D

ab 1.440,00 €

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Antifungal agent 25

Artikelnummer: TGM-T64235-100mg

Description: Antifungal agent 25 is an effective, broad-spectrum, metabolically stable antifungal agent in vivo. antifungal agent 25 exhibits antifungal effects against both Candida albicans and fluconazole-resistant Candida albicans. Target: Others

ab 1.440,00 €

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ASB14780

Artikelnummer: TGM-T64237-100mg

Description: ASB14780 is a 4-phenoxy derivative and an inhibitor of cytoplasmic phospholipase cPLA2alpha (IC50: 20 nM). Target: Others

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