Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

Für die Filterung wurden keine Ergebnisse gefunden!

LXR agonist 2

Artikelnummer: TGM-T64148-100mg

Description: LXR agonist 2 is a potent agonist of the LXR (liver X receptor). LXR agonist 2 stabilises NCOA1 (coactivator), which in turn agonises the LXR. Target: Others

MW:

586.16 D

ab 1.440,00 €

Detailansicht

Bewerten

AChE/BChE-IN-1

Artikelnummer: TGM-T64156-100mg

Description: AChE/BChE-IN-1 is a potent dual inhibitor of acetylcholinesterase and butyrylcholinesterase with blood-brain barrier permeability, exhibiting IC50 values of 1.06 nM for hAChE and 7.3 nM for hBChE, and showing antioxidant effects. AChE/BChE-IN-1 can be used in Alzheimer's disease research. Target: Others

MW:

587.11 D

ab 1.440,00 €

Detailansicht

Bewerten

MraY-IN-3

Artikelnummer: TGM-T64160-100mg

Description: MraY-IN-3 (12a) is a potent inhibitor of bacterial translocase MraY with an IC50 of 140 µM and a concentration of 46 µg/ml. Target: Others

MW:

587.75 D

ab 1.440,00 €

Detailansicht

Bewerten

XIAP degrader-1

Artikelnummer: TGM-T64161-100mg

Description: XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP). Target: Others

MW:

587.75 D

ab 1.440,00 €

Detailansicht

Bewerten

AChE-IN-5

Artikelnummer: TGM-T64162-100mg

Description: AChE-IN-5 (compound 5) is an orally active substance that effectively penetrates the blood-brain barrier and exhibits significant in vitro biological activity against AChE/5-HT1A/SERT, with an IC50 of 2.29 nM. Target: Others

MW:

587.8 D

ab 1.440,00 €

Detailansicht

Bewerten

Gln-AMS TFA

Artikelnummer: TGM-T64165-25mg

Description: Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki of 1.32 µM for glutaminyl-tRNA synthetase. Target: Others

MW:

588.47 D

ab 1.374,00 €

Detailansicht

Bewerten

EGFR-IN-18

Artikelnummer: TGM-T64170-100mg

Description: EGFR-IN-18 is a potent inhibitor of the enzymatic activity of the L858R/T790M/C797S mutant EGFR (4.9 nM) and is also able to reduce the enzymatic activity of wild-type EGFR (47 nM). Target: Others

MW:

588.68 D

ab 1.440,00 €

Detailansicht

Bewerten

LXR antagonist 2

Artikelnummer: TGM-T64171-100mg

Description: LXR antagonist 2 (compound 10rr) is a potent LXR (liver X receptor) inverse agonist, targeting LXRbeta (IC50: 0.36 µM) and LXRalpha (IC50: 2.25 µM). It serves as an adipogenesis inhibitor, downregulating LXR target genes SREBP-1c, ACC, FAS, and SCD-1, and demonstrates hypolipidemic activity in Triton...

MW:

588.76 D

ab 1.440,00 €

Detailansicht

Bewerten

MraY-IN-1

Artikelnummer: TGM-T64172-100mg

Description: MraY-IN-1 (compound 12a) is a potent inhibitor (IC50: 140 µM) of the bacterial translocase MraY. MraY-IN-1 has antibacterial activity against Escherichia coli K12 (MIC50: 7 µg/ml), Bacillus subtilis W23 (MIC50: 12 µg/ml) and Pseudomonas fluorescens Pf-5 (MIC50: 46 µg/ml). /MraY-IN-1 can be used for...

MW:

588.76 D

ab 1.440,00 €

Detailansicht

Bewerten

Cap-dependent endonuclease-IN-2

Artikelnummer: TGM-T64177-100mg

Description: Cap-dependent endonuclease-IN-2 is a potent inhibitor of cap-dependent nucleic acid endonucleases (CEN) and significantly inhibits influenza A virus RNA polymerase activity. Target: Others

MW:

589.59 D

ab 1.440,00 €

Detailansicht

Bewerten

HP590

Artikelnummer: TGM-T64182-100mg

Description: HP590 is a novel, potent, orally active STAT3 inhibitor (STAT3 luciferase activity: IC50=27.8 nM, ATP inhibition: IC50=24.7 nM). HP590 has an anti-proliferative effect on gastric cancer cells and induces apoptosis. Target: Others

MW:

590.52 D

ab 1.080,00 €

Detailansicht

Bewerten