Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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FABPs ligand 6

Artikelnummer: TGM-T62870-25mg

Description: FABPs ligand 6 (MF6) is an inhibitor of FABP5 (Kd: 874 nM) and FABP7 (Kd: 20 nM), and can be used in the study of multiple sclerosis. Target: Others

MW:

458.52 D

1.032,00 €

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LRRK2-IN-6

Artikelnummer: TGM-T62871-100mg

Description: LRRK2-IN-6 (compound 22) is an orally active, selective leucine-rich repeat protein kinase 2 (LRRK2) inhibitor with blood-brain barrier permeability, inhibiting GS LRRK2 (IC50: 4.6 µM) and WT LRRK2 (IC50: 49 µM). LRRK2-IN-6 exhibited inhibitory effects on the autophosphorylation of LRRK2 at Ser1292 and...

MW:

458.52 D

ab 1.440,00 €

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Anticancer agent 14

Artikelnummer: TGM-T62873-100mg

Description: Anticancer agent 14 is a lead compound (IC50: 0.20-0.65 µM) that blocks the cell cycle of breast cancer cells, induces apoptosis, and causes loss of mitochondrial membrane potential. Target: Others

MW:

458.59 D

ab 1.440,00 €

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Zalunfiban dihydrochloride

Artikelnummer: TGM-T62878-100mg

Description: Zalunfiban (RUC-4) dihydrochloride is a selective and potent platelet alphaIIbbeta3 antagonist with an IC50 of 45 nM, suitable for studying myocardial infarction. Target: Others

MW:

459.35 D

ab 1.023,00 €

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alpha-Glucosidase-IN-19

Artikelnummer: TGM-T62891-100mg

Description: Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 µM) with antidiabetic effects. Target: Others

MW:

459.6 D

ab 1.440,00 €

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AZ-PFKFB3-67 quarterhydrate

Artikelnummer: TGM-T62894-100mg

Description: AZ-PFKFB3-67 quarterhydrate is a selective and potent inhibitor of the metabolic kinase PFKFB3 kinase, acting on PFKFB3 (IC50: 11 nM), PFKFB2 (IC50: 159 nM) and PFKFB1 (IC50: 1130 nM). Target: Others

MW:

460.01 D

ab 1.127,00 €

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EZH2-IN-12

Artikelnummer: TGM-T62896-100mg

Description: EZH2-IN-12 (Compound 5) is a potent inhibitor of EZH2, which has potential for studies of CNS malignancies. Target: Others

MW:

460.35 D

ab 1.440,00 €

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GLS-1-IN-1

Artikelnummer: TGM-T62905-100mg

Description: GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor effective against Hep G2, MCF 7, and MCF 10A cells. Target: Others

MW:

460.57 D

ab 1.440,00 €

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TAS-117 hydrochloride

Artikelnummer: TGM-T62907-25mg

Description: TAS-117 hydrochloride is a selective, potent, orally active allosteric Akt inhibitor, acting on Akt1 (IC50: 4.8 nM), Akt2 (IC50: 1.6 nM) and Akt3 (IC50: 44 nM). TAS-117 hydrochloride stimulates anti-myeloma activity, enhances lethal endoplasmic reticulum stress induced by proteasome inhibition, and can...

MW:

460.96 D

ab 1.763,00 €

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Antibacterial agent 62

Artikelnummer: TGM-T62910-100mg

Description: Antibacterial agent 62 is a novel redox cycle anti-tuberculosis compound exhibiting significant bactericidal activity against both growing and phenotypically resistant non-growing (nutrient deficient) bacteria. Target: Others

MW:

461.44 D

ab 1.440,00 €

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