Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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URAT1 inhibitor 3

Artikelnummer: TGM-T60724-100mg

Description: URAT1 inhibitor 3 is a potent, orally active, selective inhibitor of URAT1 (IC50 = 0.8 nM) demonstrating urate-lowering efficacy, suitable for research in gout and hyperuricemia [1]. Target: Others

MW:

307.13 D

ab 1.440,00 €

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TMX-4113

Artikelnummer: TGM-T60740-100mg

Description: TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1alpha(CK1alpha) degrader [1]. Target: Others

MW:

308.38 D

ab 1.327,00 €

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HDAC10-IN-2

Artikelnummer: TGM-T60760-100mg

Description: HDAC10-IN-2 (compound 10c) is a potent and highly selective HDAC10 inhibitor (IC50 = 20 nM) that regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1]. Target: Others

MW:

310.39 D

ab 1.440,00 €

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MMG-11 quarterhydrate

Artikelnummer: TGM-T60763-100mg

Description: MMG-11 quarterhydrate is a potent and selective antagonist of human TLR2, inhibiting both TLR2/1 and TLR2/6 signaling with low cytotoxicity. The IC50 values for Pam3CSK4-induced hTLR2/1 and Pam2CSK4-induced hTLR2/6 responses are 1.7 µM and 5.7 µM, respectively [1]. Target: Others

MW:

310.78 D

ab 1.156,00 €

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COX-2/PI3K-IN-2

Artikelnummer: TGM-T60769-100mg

Description: COX-2/PI3K-IN-2 (compound 5f) possesses anti-inflammatory and anti-cancer properties, functioning as a selective inhibitor of COX-2 (Ki = 3.02 nM) and a potent inhibitor of PI3K (IC50 = 2.78 nM) [1]. Target: Others

MW:

311.34 D

ab 1.440,00 €

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ERRgamma agonist-1

Artikelnummer: TGM-T60772-100mg

Description: ERRgamma agonist-1 can be used in neuropsychological disorders research. ERRgamma agonist-1 increases the ERRgamma transcriptional activities that is a potent agonist of ERRgamma [1]. Target: Others

MW:

311.38 D

ab 1.440,00 €

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Anti-Influenza agent 3

Artikelnummer: TGM-T60778-100mg

Description: Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with low cytotoxicity for MDCK epithelial cells, inhibiting the M2 WT and S31N ion channel conductivity. It has an EC50 value of 3.29 µM for A/HK/68 (H3N2, M2-WT) and 2.45 µM for A/WSN/33 (H1N1, M2-S31N) strain [1]. Target: Others

MW:

311.87 D

ab 1.440,00 €

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CD73-IN-13

Artikelnummer: TGM-T60779-100mg

Description: CD73-IN-13 is able to be used in a medicament preparing for tumor-related diseases. CD73-IN-13 is a potent inhibitor of CD73 which is closely associated with tumor growth, angiogenesis and metastasis [1]. Target: Others

MW:

312.25 D

ab 1.440,00 €

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Aurora/LIM kinase-IN-1

Artikelnummer: TGM-T60783-100mg

Description: Aurora/LIM kinase-IN-1 (Compound F114) is a potent dual inhibitor of aurora and LIM kinases. It inhibits the proliferation and invasion of glioblastoma multiforme (GBM), making it a potential candidate for drug development in GBM and other cancers. Aurora and LIM kinases are involved in neoplastic cell...

MW:

312.37 D

ab 1.440,00 €

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SARS-CoV-2-IN-6

Artikelnummer: TGM-T60785-100mg

Description: SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with an IC50 value of 73 nM. Target: Others

MW:

312.75 D

ab 945,00 €

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5-HT7R antagonist 1

Artikelnummer: TGM-T60790-100mg

Description: 5-HT7R antagonist 1 is a G protein-biased antagonist with a Ki of 6.5 nM for 5-HT7R. Target: Others

MW:

313.23 D

ab 1.440,00 €

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Antitubercular agent-11

Artikelnummer: TGM-T60791-100mg

Description: Antitubercular agent-11 (Compound 1e) contains a bulkier electron-donating group (Bu-t) and exhibits the best MIC value of 0.060 µg/mL [1]. Target: Others

MW:

313.31 D

ab 1.440,00 €

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