Produkte von TargetMol
TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.
Mehr Informationen unter: www.targetmol.com
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EGFR/HER2/DHFR-IN-1
Artikelnummer: TGM-T61596-100mg
Description: EGFR/HER2/DHFR-IN-1 is a highly selective and potent anticancer compound targeting MCF-7 breast cancer cells, acting as a multi-inhibitor for EGFR/HER2 kinase and DHFR enzymes, with IC50 values of 0.153 µM, 0.108 µM, and 0.291 µM, respectively. It induces cell cycle arrest at the G1/S phase and...
| MW: | 379.23 D |
ab 1.440,00 €
TLR7/8 antagonist 2
Artikelnummer: TGM-T61601-100mg
Description: TLR7/8 antagonist 2 (Compound 15) is a highly potent and orally active agonist of TLR7/8 with IC50 values of 4.9 nM for TLR7 and 0.6 nM for TLR8, making it a promising candidate for treating and investigating autoimmune diseases like lupus erythematosus, which involves inappropriate activation of TLR7...
| MW: | 379.47 D |
ab 1.440,00 €
Anticancer agent 35
Artikelnummer: TGM-T61602-100mg
Description: Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent that inhibits A549, A431, and PACA2 cell growth with IC50 values of 18.1 µg/mL, 4.0 µg/mL, and 18.9 µg/mL, respectively [1]. Target: Others
| MW: | 379.48 D |
ab 1.440,00 €
H3R antagonist 2
Artikelnummer: TGM-T61603-100mg
Description: H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist with inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of 180 nM, 880 nM, and 775 nM, respectively. With a Ki of 170 nM for hH3R, it demonstrates...
| MW: | 379.49 D |
ab 1.440,00 €
Hcyb1
Artikelnummer: TGM-T61617-100mg
Description: Hcyb1 is a potent and specific inhibitor of phosphodiesterase 2 (PDE2). It exhibits a high degree of selectivity for inhibiting PDE2A with an IC50 value of 0.57 µM. In addition, Hcyb1 displays over 250-fold selectivity against other recombinant members of the PDE family. Moreover, its pharmacological...
| MW: | 380.44 D |
ab 867,00 €
XN methyl pyrazole
Artikelnummer: TGM-T61619-100mg
Description: XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1]. Target: Others
| MW: | 380.44 D |
ab 1.440,00 €
AChE/PDE4-IN-1
Artikelnummer: TGM-T61620-100mg
Description: AChE/PDE4-IN-1 (compound 12c) is a highly effective and specific dual inhibitor of PDE4 and AChE, with IC50 values of 0.28 µM for AChE and 1.88 µM for PDE4D. This compound shows notable potential in reducing neuroinflammation associated with Alzheimer's disease research [1]. Target: Others
| MW: | 380.48 D |
ab 1.440,00 €
GABAA receptor agonist 2
Artikelnummer: TGM-T61625-100mg
Description: GABAA receptor agonist 2 (compound 4c) is a highly potent compound that exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, it produces GABAergic effects. Notably, compound 4c holds promise for...
| MW: | 380.52 D |
ab 1.440,00 €
iMDK quarterhydrate
Artikelnummer: TGM-T61627-100mg
Description: iMDK quarterhydrate, a potent PI3K inhibitor, is effective in inhibiting the growth factor MDK (also known as midkine or MK) while demonstrating suppression of non-small cell lung cancer (NSCLC). In combination with a MEK inhibitor, iMDK quarterhydrate demonstrates cooperative inhibition of NSCLC...
| MW: | 380.91 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
IAB15
Artikelnummer: TGM-T60648-100mg
Description: IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1]. Target: Others
| CAS | 2987139-91-1 |
| MW: | 297.27 D |
ab 1.440,00 €
Monoamine Oxidase B inhibitor 1
Artikelnummer: TGM-T60656-100mg
Description: Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active, and selective monoamine oxidase B (MAO-B) inhibitor (IC50 = 0.02 nM) capable of crossing the blood-brain barrier (BBB). It exhibits antioxidant and anti-neuroinflammatory activities and can be used in the study of Parkinson's...
| MW: | 298.31 D |
ab 1.440,00 €
hMAO-B/MB-COMT-IN-2
Artikelnummer: TGM-T60658-100mg
Description: hMAO-B/MB-COMT-IN-2 is a dual inhibitor of MAO-B/MB-COMT with IC50s of 4.27 µM and 2.69 µM for hMAO-B and MB-COMT, respectively. hMAO-B/MB-COMT-IN-2 protects cells from oxidative damage and can be used in neurodegeneration disease research, such as Parkinson's Disease (PD) [1]. Target: Others
| MW: | 298.34 D |
ab 1.440,00 €