Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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Brinzolamide hydrochloride

Artikelnummer: TGM-T64241-100mg

Description: Brinzolamide (AL-4862) hydrochloride is a selective inhibitor (IC50: 3.2 nM) of carbonic anhydrase II, inhibiting ciliary CA-II, reducing atrial fluid secretion, and thereby lowering intraocular pressure (IOP). It is useful for studying glaucoma disease. Target: Others

ab 1.440,00 €

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CCR1 antagonist 11 hydrochloride

Artikelnummer: TGM-T64242-100mg

Description: CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist with IC50 values of 0.03 µM for hCCR1, 0.58 µM for mCCR1, and 0.32 µM for rCCR1. This compound is useful for studying rheumatoid arthritis and other related inflammatory diseases. Target: Others

ab 1.440,00 €

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CDK4/6-IN-10

Artikelnummer: TGM-T64244-100mg

Description: CDK4/6-IN-10 is a selective, potent, orally active inhibitor of CDK4 (IC50: 22 nM) and CDK6 (IC50: 10 nM) with antitumour effects, showing potential for studies in multiple myeloma (MM). Target: Others

ab 1.440,00 €

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CDK8-IN-9

Artikelnummer: TGM-T64245-100mg

Description: CDK8-IN-9 (compound 22) is a potent type II CDK8 inhibitor (IC50: 48.6 nM) with demonstrated inhibitory effects on tumor growth, making it a valuable tool for studying colorectal cancer. Target: Others

ab 1.440,00 €

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CREB-IN-1 TFA

Artikelnummer: TGM-T64247-100mg

Description: CREB-IN-1 TFA is a potent and orally active CREB inhibitor with an IC50 of 0.18 µM, exhibiting inhibitory effects on the growth of breast cancer cells. Target: Others

ab 1.440,00 €

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Cyclic-di-GMP sodium

Artikelnummer: TGM-T64248-25mg

Description: Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility and virulence of various bacteria. Target: Others

ab 1.470,00 €

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CYP11B1-IN-2

Artikelnummer: TGM-T64249-100mg

Description: CYP11B1-IN-2 (compound 7aa) is a selective, orally active inhibitor of CYP11B1 with an IC50 of 9 nM for human CYP11B1 and 25 nM for rat CYP11B1. It can be used to study diseases caused by cortisol overload. Target: Others

ab 1.440,00 €

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Diguanosine 5'-triphosphate lithium

Artikelnummer: TGM-T64251-100mg

Description: Diguanosine 5'-triphosphate (Gp3G) lithium, a dinucleoside triphosphate and virus-specific oligonucleotide, is required for RNA synthesis during transcription. Target: Others

ab 1.440,00 €

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EGFR/HER2-IN-4

Artikelnummer: TGM-T64253-100mg

Description: EGFR/HER2-IN-4 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM). EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer. Target:...

ab 1.440,00 €

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EGFR/HER2-IN-5

Artikelnummer: TGM-T64254-100mg

Description: EGFR/HER2-IN-5 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM). EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer. Target:...

ab 1.440,00 €

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EGFR-IN-48

Artikelnummer: TGM-T64255-100mg

Description: EGFR-IN-48 is a potent, orally active EGFR inhibitor that acts on EGFRd19/TM/CS (IC50: 0.193 nM), EGFRLR/TM/CS (IC50: 0.251 nM), EGFRWT (IC50: 10.4 nM). EGFR-IN-48 is also able to inhibit EGFR-IN-48 also inhibits the proliferation of BaF3EGFR del19/T790M/C797S cells (IC50: 1.526 nM) and PC-9EGFR...

ab 1.440,00 €

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FXIa-IN-8

Artikelnummer: TGM-T64257-100mg

Description: FXIa-IN-8, a potent and selective inhibitor of FXIa (IC50: 14.2 nM), exhibits anti-thrombotic effects without increasing the risk of bleeding or causing significant toxicity [1]. Target: Others

ab 1.440,00 €

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