Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

Für die Filterung wurden keine Ergebnisse gefunden!

CXCR2 antagonist 5

Artikelnummer: TGM-T61235-100mg

Description: CXCR2 antagonist 5 (compound 25) is a potent CXCR2 antagonist with strong binding affinity (IC50 = 0.013 µM) and effective calcium mobilization (IC50 = 0.1 µM) [1]. Target: Others

MW:

352.36 D

ab 1.440,00 €

Detailansicht

Bewerten

CXCR2 antagonist 7

Artikelnummer: TGM-T61236-100mg

Description: CXCR2 antagonist 7 (compound 19) is a potent CXCR2 antagonist with strong binding affinity (IC50 = 0.044 µM) and calcium mobilization (IC50 = 0.66 µM) [1]. Target: Others

MW:

352.36 D

ab 1.440,00 €

Detailansicht

Bewerten

HDAC-IN-32

Artikelnummer: TGM-T61248-100mg

Description: HDAC-IN-32 is a highly effective HDAC inhibitor presenting IC50 values of 5.2, 11, and 28 nM for HDAC1, HDAC2, and HDAC6, respectively. This compound demonstrates notable anti-proliferative properties against tumor cells, as well as significant in vivo antitumor efficacy, which can elicit antitumor...

MW:

353.41 D

ab 1.440,00 €

Detailansicht

Bewerten

Antitubercular agent-16

Artikelnummer: TGM-T61252-100mg

Description: Antitubercular agent-16 (Compound 5q) is a potent antitubercular agent exhibiting high efficacy against various strains of M. tuberculosis, including H37Rv, CF16, CF61, CF76, CF152, and CF161, with MIC 90 values ranging from 0.40 to 23.51 µg/mL. Notably, Antitubercular agent-16 demonstrates minimal...

MW:

353.52 D

ab 1.440,00 €

Detailansicht

Bewerten

Antifungal agent 19

Artikelnummer: TGM-T61257-100mg

Description: Antifungal agent 19 demonstrates potent antifungal activity (EC50 = 0.72 µM). Target: Others

MW:

354.34 D

ab 1.440,00 €

Detailansicht

Bewerten

hCA IX-IN-1

Artikelnummer: TGM-T61263-100mg

Description: hCA IX-IN-1 (Compound 6f) is a human carbonic anhydrase ( hCA ) inhibitor with K i values of 331.4, 28.4, 9.4 and 17.8 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. hCA IX-IN-1 shows anticancer activity [1]. Target: Others

MW:

354.42 D

ab 1.440,00 €

Detailansicht

Bewerten

EGFR/HER2-IN-7

Artikelnummer: TGM-T61272-100mg

Description: EGFR/HER2-IN-7 is a highly selective and potent anticancer compound designed to target MCF-7 breast cancer cells by functioning as a dual inhibitor of EGFR/HER2 kinases and DHFR (dihydrofolate reductase), with IC50 values of 0.18 µM for EGFR, 0.146 µM for HER2, and 0.907 µM for DHFR [1]. Target: Others

MW:

355.45 D

ab 1.440,00 €

Detailansicht

Bewerten

TS010

Artikelnummer: TGM-T61279-100mg

Description: TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 µM. It holds significant promise for advancements in cancer research [1]. Target: Others

MW:

356.36 D

ab 1.440,00 €

Detailansicht

Bewerten

CYP121A1-IN-1

Artikelnummer: TGM-T61287-100mg

Description: CYP121A1-IN-1 is a potent inhibitor of CYP121A1, demonstrating favorable activity against Mycobacterium tuberculosis (H37Rv MIC 90 ~6.25 µM, ~2.2 µg/mL). It significantly reduces mycocyclosin production by blocking the CYP121A1-mediated conversion of cyclo(l-tyrosyl-l-tyrosyl) to mycocyclosin [1]....

MW:

356.42 D

ab 1.440,00 €

Detailansicht

Bewerten

CAII-IN-1

Artikelnummer: TGM-T61292-100mg

Description: CAII-IN-1 (compound 3n) is a thiosemicarbazide derivative that acts as a potent and selective inhibitor of carbonic anhydrase-II (CA-II), with an IC50 value of 10.3 µM for bovine CA-II. This compound (CAII-IN-1) is useful in research on carbonic anhydrase-associated biological disorders [1]. Target: Others

MW:

356.46 D

ab 1.440,00 €

Detailansicht

Bewerten

PDE4-IN-5

Artikelnummer: TGM-T61295-100mg

Description: PDE4-IN-5 (compound 33a) is a highly potent and selective PDE4 inhibitor with an IC50 value of 3.1 nM, exhibiting excellent skin permeability and a well-characterized binding mechanism. It also shows a notable anti-psoriasis effect [1]. Target: Others

MW:

356.46 D

ab 1.440,00 €

Detailansicht

Bewerten

LasR-IN-3

Artikelnummer: TGM-T61305-100mg

Description: LasR-IN-3, a chemical compound, acts as an inhibitor of LasR in Pseudomonas aeruginosa. It induces structural instability in LasR and causes complete dissociation of its functioning dimeric form [1]. Target: Others

MW:

357.41 D

ab 1.440,00 €

Detailansicht

Bewerten

12259 von 12274 Seiten