Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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ZIKV-IN-4

Artikelnummer: TGM-T63533-100mg

Description: ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 µM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase. Target: Others

MW:

511.65 D

ab 1.440,00 €

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FAK-IN-3

Artikelnummer: TGM-T63545-100mg

Description: FAK-IN-3 is a potent inhibitor of adherens spot kinase (FAK). FAK-IN-3 reduces migration and invasion of PA-1 cells and inhibits the expression of MMP-2 and MMP-9. FAK-IN-3 inhibits tumor growth and metastasis with no significant adverse effects. FAK-IN-3 has shown investigational potential in ovarian...

MW:

512.56 D

ab 1.440,00 €

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MEK1/2-IN-2

Artikelnummer: TGM-T63547-100mg

Description: MEK1/2-IN-2 is a potent, ATP-competitive MEK1/2 inhibitor that exhibits equal inhibitory effects on both wild-type MEK1/2 and a range of MEK1/2 mutant cells. Target: Others

MW:

512.97 D

ab 1.440,00 €

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MRGPRX1 agonist 4

Artikelnummer: TGM-T63549-100mg

Description: MRGPRX1 agonist 4 is a potent and orally active Mas-related G protein-coupled receptor X1 (MRGPRX1) positive conformation modulator (EC50: 0.1 µM). MRGPRX1 agonist 4 ameliorated the behavioral thermal allergic response in mice, a model of MRGPRX1 neuropathic pain. Target: Others

MW:

513.36 D

ab 1.440,00 €

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Complex III-IN-1

Artikelnummer: TGM-T61009-100mg

Description: Complex III-IN-1 (Compd 4c-2) is an inhibitor of complex III with antifungal activity, exhibiting an EC50 value of 18.53 mg/L against Sclerotinia sclerotiorum [1]. Target: Others

MW:

333.9 D

ab 1.440,00 €

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Galectin-8-IN-1

Artikelnummer: TGM-T61014-100mg

Description: Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N) with a Kd value of 48 µM, demonstrating 15-fold greater selectivity compared to galectin-3 and outperforming other mammalian galectins. Target: Others

MW:

334.32 D

ab 1.440,00 €

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Topoisomerase II inhibitor 6

Artikelnummer: TGM-T61017-100mg

Description: Topoisomerase II inhibitor 6 (Compound 5), a tryptanthrin derivative, is a potent and selective topoisomerase II inhibitor that blocks the CCRF-CEM cell cycle in the G2 phase and induces DNA double-strand breaks (DSB). It exhibits antiproliferative activity on various tumor cell lines and has potential...

MW:

334.37 D

ab 1.440,00 €

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FAK-IN-4

Artikelnummer: TGM-T61019-100mg

Description: FAK-IN-4 (Compound 7d) exhibits anticancer activities by inducing cell apoptosis and is a potential inhibitor of FAK [1]. Target: Others

MW:

334.41 D

ab 1.440,00 €

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LSD1-IN-16

Artikelnummer: TGM-T61021-100mg

Description: LSD1-IN-16 (compound 4b) is a potent inhibitor of LSD1 that inhibits LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.015, 0.024, and 0.366 µM, respectively. LSD1-IN-16 also induces cell growth arrest in prostate cancer LNCaP cells with an IC50 value of 15.2 µM [1]. Target: Others

MW:

334.43 D

ab 1.440,00 €

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LSD1-IN-17

Artikelnummer: TGM-T61022-100mg

Description: LSD1-IN-17 (compound 5b) is a potent inhibitor of LSD1, effectively inhibiting LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.005, 0.028, and 0.820 µM, respectively. It induces cell growth arrest in prostate cancer LNCaP cells with an IC50 value of 17.2 µM [1]. Target: Others

MW:

334.43 D

ab 1.440,00 €

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HIV-1 inhibitor-41

Artikelnummer: TGM-T61031-100mg

Description: HIV-1 inhibitor-41 (Compound B23) is an orally active non-nucleoside HIV-1 reverse transcriptase inhibitor with EC50 values of 50 nM against the mutant E138K strain and 20.8 nM against HIV-1 WT. HIV-1 inhibitor-41 exhibits low hERG inhibition, no apparent CYP enzymatic inhibition, and no acute toxicity...

MW:

335.37 D

ab 1.440,00 €

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Carbonic anhydrase inhibitor 10

Artikelnummer: TGM-T61032-100mg

Description: Carbonic anhydrase inhibitor 10 can be used in the research of cancer that shows anti-proliferative activity against MCF-7 cancer cell line with an IC50 of 11.9 µM. Carbonic anhydrase inhibitor 10 is a potent inhibitor of h CA IX with a Ki value of 6.2 nM [1]. Target: Others

MW:

335.38 D

ab 1.440,00 €

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