Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

Für die Filterung wurden keine Ergebnisse gefunden!

PTP1B-IN-18

Artikelnummer: TGM-T63022-100mg

Description: PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 35.2 µM, and it can be used for the study of type 2 diabetes. Target: Others

MW:

469.51 D

ab 1.440,00 €

Detailansicht

Bewerten

PTP1B-IN-19

Artikelnummer: TGM-T63023-100mg

Description: PTP1B-IN-19 (Compound 43) is a promising selective benzimidazole derivative that acts as a protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 23.3 µM. This compound, along with PTP1B-IN-17, can be utilized in the study of type 2 diabetes. Target: Others

MW:

469.51 D

ab 1.440,00 €

Detailansicht

Bewerten

JAK-IN-19

Artikelnummer: TGM-T63026-100mg

Description: JAK-IN-19 is a potent JAK inhibitor with pIC50 values of 7.2 for PBMC (IFNgamma) and 7.7 for HLF (Eotaxin). The compound also exhibits pIC50 values of 7.0 for VEGFR2 and 5.8 for Aurora B. Target: Others

MW:

469.59 D

ab 1.440,00 €

Detailansicht

Bewerten

Antibacterial agent 66

Artikelnummer: TGM-T63027-100mg

Description: Antibacterial agent 66 (Compound 6q) is a trifluoromethylpyridine 1,3,4-oxadiazole derivative active against Xanthomonas oryzae pv. oryzae (Xoo) (EC50: 7.2 µg/mL). Target: Others

MW:

469.79 D

ab 1.440,00 €

Detailansicht

Bewerten

KRAS G12D inhibitor 12

Artikelnummer: TGM-T63028-100mg

Description: KRAS G12D inhibitor 12 is an effective inhibitor of KRAS G12D. The Ras protein family is an important intracellular signaling molecule, which plays an important role in growth and development. KRAS G12D inhibitor 12 has the potential to perform KRAS G12D-mediated cancer studies. Target: Others

MW:

469.9 D

ab 1.440,00 €

Detailansicht

Bewerten

TIM-3-IN-1

Artikelnummer: TGM-T63029-100mg

Description: TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer. Target: Others

MW:

469.9 D

ab 1.440,00 €

Detailansicht

Bewerten

P-gp modulator 2

Artikelnummer: TGM-T63032-100mg

Description: P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic modulator of P-glycoprotein (P-gp). Target: Others

MW:

470.32 D

ab 1.440,00 €

Detailansicht

Bewerten

MsbA-IN-4

Artikelnummer: TGM-T63033-100mg

Description: MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 µM). Target: Others

MW:

470.33 D

ab 1.440,00 €

Detailansicht

Bewerten

IDO1-IN-13

Artikelnummer: TGM-T63034-100mg

Description: IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. It inhibits cell IDO1 with an EC50 of 30 nM for HeLa cells and reduces the kyn/trp ratio by 51% in SK-OV-3 xenograft tumor tissue. Target: Others

MW:

470.34 D

ab 1.440,00 €

Detailansicht

Bewerten

Anti-inflammatory agent 18

Artikelnummer: TGM-T63473-100mg

Description: Anti-inflammatory agent 18 inhibits NO activity (IC50: 15.94 µM) and has an inhibitory effect on the late inflammatory response induced by HMGB1 and can be used to study late inflammatory diseases such as coronavirus disease (COVID-19), sepsis, etc. Target: Others

MW:

506.71 D

ab 1.440,00 €

Detailansicht

Bewerten

PI3Kalpha-IN-8

Artikelnummer: TGM-T63477-100mg

Description: PI3Kalpha-IN-8 is a selective inhibitor of PI3Kalpha (IC50: 0.012 µM). PI3Kalpha-IN-8 increases intracellular levels of reactive oxygen species, decreases mitochondrial membrane potential, and induces apoptosis. Target: Others

MW:

507.42 D

ab 1.440,00 €

Detailansicht

Bewerten