Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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Axl-IN-3

Artikelnummer: TGM-T62962-100mg

Description: Axl-IN-3 is a selective, potent and orally active inhibitor of AXL kinase (IC50: 41.5 nM) and has a low inhibitory effect on other kinases. Target: Others

MW:

464.95 D

ab 1.440,00 €

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Anti-inflammatory agent 10

Artikelnummer: TGM-T62967-100mg

Description: Anti-inflammatory agent 10 is a tilomisole-based benzimidazole-thiazole derivative that is orally active. anti-inflammatory agent 10 is more active against COX-2 enzymes than COX-1. Target: Others

MW:

465.34 D

ab 1.440,00 €

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PDE4-IN-6

Artikelnummer: TGM-T62969-100mg

Description: PDE4-IN-6 is a safe, potent and moderately selective inhibitor of PDE4, acting on PDE4B (IC50: 0.125 µM) and PDE4D (IC50: 0.43 µM). PDE4-IN-6 is able to down-regulate TNF-alpha and IL-6 expression levels, exhibits anti-inflammatory and anti-arthritic effects, and has potent immunomodulatory activity....

MW:

465.49 D

ab 1.440,00 €

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Carbonic anhydrase inhibitor 5

Artikelnummer: TGM-T62976-100mg

Description: Carbonic anhydrase inhibitor 5 is a potent and selective inhibitor of human carbonic anhydrase (hCA), targeting hCA II (IC50: 42.9 nM), hCA IX (IC50: 47.6 nM), and hCA XII (IC50: 6.7 nM). Target: Others

MW:

465.95 D

ab 1.440,00 €

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HIV-IN-3

Artikelnummer: TGM-T62978-100mg

Description: HIV-IN-3 (Compound 22a) is a potent HIV inhibitor (IC50: 1.5 µM) with potential for studying HIV-related diseases. Target: Others

MW:

465.98 D

ab 1.440,00 €

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iNOs-IN-1

Artikelnummer: TGM-T62987-100mg

Description: iNOs-IN-1 (YPW) is a potent inhibitor of inducible nitric oxide synthase (iNOS) with anti-inflammatory effects, significantly inhibiting IL-6 and iNOS expression in a dose-dependent manner in murine macrophages, and also inhibiting LPS-induced NO generation. Target: Others

MW:

466.53 D

ab 867,00 €

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IRAK4-IN-12

Artikelnummer: TGM-T62989-100mg

Description: IRAK4-IN-12 (compound 37) is a potent inhibitor of IRAK4 with an IC50 of 0.015 µM and demonstrates cellular pIRAK4 potency with an IC50 of 0.5 µM. Target: Others

MW:

466.55 D

ab 1.440,00 €

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PI3K/AKT-IN-1

Artikelnummer: TGM-T62997-100mg

Description: PI3K/AKT-IN-1 is a potent, dual PI3K/AKT inhibitor that acts on PI3Kgamma (IC50: 6.99 µM), PI3Kdelta (IC50: 4.01 µM) and AKT (IC50: 3.36 µM). PI3K/AKT-IN-1 induces caspase 3-dependent apoptosis by inhibiting the PI3K/AKT pathway. caspase 3-dependent apoptosis and exhibited anticancer effects. Target:...

MW:

467.54 D

ab 393,00 €

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VEGFR-2-IN-15

Artikelnummer: TGM-T63002-100mg

Description: VEGFR-2-IN-15 (Compound 14b) is a potent VEGFR-2 inhibitor that inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis. Target: Others

MW:

467.92 D

ab 1.440,00 €

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DHU-Se1

Artikelnummer: TGM-T63006-100mg

Description: DHU-Se1 is a potent anti-inflammatory agent that stimulates the release of reactive selenium compounds from macrophages and reduces the expression of cellular inflammatory factors such as iNOS and TNF-alpha. Additionally, DHU-Se1 blocks the polarization of macrophages from M0 to M1, thereby alleviating...

MW:

468.47 D

ab 1.440,00 €

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SphK2-IN-2

Artikelnummer: TGM-T63017-100mg

Description: SphK2-IN-2 (21g) is a potent and selective SphK2 inhibitor with an IC50 of 0.23 µM. Target: Others

MW:

468.94 D

ab 1.440,00 €

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GKA50 quarterhydrate

Artikelnummer: TGM-T63019-100mg

Description: GKA50 quarterhydrate is a potent glucokinase activator with an EC50 value of 33 nM. This glucose-like activator of beta-cell metabolism in rodent and human pancreatic islets is a Ca2+-dependent regulator of insulin secretion. It stimulates insulin secretion in mouse islets and significantly reduces...

MW:

469.01 D

ab 1.251,00 €

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