Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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Antiangiogenic agent 2

Artikelnummer: TGM-T62931-100mg

Description: Antiangiogenic agent 2 (compound 3b) is a potent thymidine phosphorylase inhibitor (IC50: 39.71 µM) with demonstrated anti-angiogenic effects. Target: Others

MW:

463.5 D

ab 1.440,00 €

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NS2B/NS3-IN-2

Artikelnummer: TGM-T62932-100mg

Description: NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 with an IC50 of 6.0 nM and a Ki of 0.66 µM. It significantly increases cell viability and exhibits no cytotoxicity. Target: Others

MW:

463.51 D

ab 1.440,00 €

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ZLHQ-5f

Artikelnummer: TGM-T62934-100mg

Description: ZLHQ-5f is a dual inhibitor of CDK2 and Topo I, acting on CDK2/CycA2 (IC50: 0.145 µM). ZLHQ-5f has a good safety profile by blocking the cell cycle of HCT116 cells in S phase and inducing apoptosis. Target: Others

MW:

463.53 D

ab 1.440,00 €

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Anticancer agent 26

Artikelnummer: TGM-T62935-100mg

Description: Anticancer agent 26 is a promising candidate for cancer therapy and deserves further development. Target: Others

MW:

463.57 D

ab 1.440,00 €

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SHR2415

Artikelnummer: TGM-T62939-100mg

Description: SHR2415 is a selective, potent, orally active inhibitor of ERK1/2. SHR2415 inhibits ERK1 (IC50: 2.8 nM) and ERK2 (IC50: 5.9 nM). SHR2415 exhibits high potency in Colo205 cells (IC50: 44.6 nM). SHR2415 can be used in cancer research. Target: Others

MW:

463.92 D

ab 1.440,00 €

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ZLWT-37

Artikelnummer: TGM-T62943-100mg

Description: ZLWT-37 is a potent, orally active inhibitor of CDKs, specifically targeting CDK9 (IC50: 0.002 µM) and CDK2 (IC50: 0.054 µM), and is capable of blocking the cell cycle of HCT116 cells in G2/M phase and inducing apoptosis. Target: Others

MW:

464 D

ab 1.440,00 €

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Dopamine D3 receptor antagonist-2

Artikelnummer: TGM-T62946-100mg

Description: Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor-selective compound (Ki=2.16 nM) that exhibits potential therapeutic effects in CNS disorders. Target: Others

MW:

464.38 D

ab 1.440,00 €

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(1R,3S)-THCCA-Asn

Artikelnummer: TGM-T62949-100mg

Description: (1R,3S)-THCCA-Asn (4j) is a selective inhibitor of thrombin with an IC50 range of 0.07-0.14 µM and exhibits anti-thrombotic effects. Target: Others

MW:

464.47 D

ab 1.440,00 €

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IRAK4-IN-18

Artikelnummer: TGM-T62950-100mg

Description: IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). It inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats, making it useful for studying arthritic diseases. Target: Others

MW:

464.49 D

ab 1.440,00 €

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PARP1-IN-5

Artikelnummer: TGM-T62955-100mg

Description: PARP1-IN-5 is a potent, selective, orally active, low-toxicity PARP-1 inhibitor with an IC50 value of 14.7 nM. PARP1-IN-5 can be used in cancer research. Target: Others

MW:

464.53 D

ab 1.440,00 €

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RORgammat inverse agonist 29

Artikelnummer: TGM-T62956-100mg

Description: RORgammat inverse agonist 29 is a potent, selective, and orally active compound with an IC50 value of 21 nM. It can be utilized in the study of autoimmune diseases, including skin inflammation and psoriasis. Target: Others

MW:

464.53 D

ab 1.440,00 €

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ZK824859 hydrochloride

Artikelnummer: TGM-T62961-100mg

Description: ZK824859 hydrochloride is a selective, orally active inhibitor of urokinase-type fibrinogen activator (uPA) with IC50 values of 79 nM, 1580 nM and 1330 nM for human uPA, tPA and fibrin, respectively. Target: Others

MW:

464.89 D

ab 934,00 €

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