Produkte von TargetMol

TargetMol aus Boston (Massachusetts) wurde 2015 gegründet und ist ein Experte für Wirkstoffscreening in der Life Science-Community. Das Unternehmen bietet diverse Substanzbibliotheken, darunter FDA-zugelassene Bibliotheken, an und deckt ein breites Spektrum an niedermolekularen Verbindungen wie Inhibitoren und Agonisten sowie rekombinante Proteine und Naturstoffe ab. Die Produkte von TargetMol werden von Forschenden weltweit in Bereichen wie Krebsforschung, Neurobiologie, Inflammation, Immunologie oder Metabolismus eingesetzt.

Mehr Informationen unter: www.targetmol.com

Zu den Katalogen von TargetMol

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PPARalpha agonist 1

Artikelnummer: TGM-T62266-100mg

Description: PPARalpha agonist 1 is a complete and potent PPARalpha agonist. Target: Others

MW:

422.56 D

ab 1.440,00 €

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HER2-IN-9

Artikelnummer: TGM-T62271-100mg

Description: HER2-IN-9, an orally active HER2 inhibitor (IC50: 0.03 µM), inhibits the proliferation and migration of HER-2-positive breast cancer cells and is employed in breast cancer research. Target: Others

MW:

423.23 D

ab 1.440,00 €

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BET-IN-8

Artikelnummer: TGM-T62275-100mg

Description: BET-IN-8 (Compound 27) is a potent BET inhibitor (Ki: 0.83 µM, Kd: 0.571 µM) that ameliorates LPS-induced sepsis in vivo, showing potential in sepsis treatment. Target: Others

MW:

423.48 D

ab 1.440,00 €

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Anticancer agent 36

Artikelnummer: TGM-T62278-100mg

Description: Anticancer agent 36 (compound 11) is a potent anti-microbial and anti-cancer agent, a sulfonylurea derivative. anticancer agent 36 inhibits the microbial growth of Bacillus mycoides, Escherichia coli and Candida albicans (MIC: 0.156 - 0.039 mg/mL). Anticancer agent 36 inhibited the growth of A549 cells...

MW:

423.51 D

ab 1.440,00 €

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Antifungal agent 17

Artikelnummer: TGM-T62280-100mg

Description: Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 µg/mL). Target: Others

MW:

424.13 D

ab 1.440,00 €

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AD013

Artikelnummer: TGM-T62288-100mg

Description: AD013 is a dual cACE and NEP inhibitor. AD013 is a C-domain selective ACE inhibitor of lenopril-tryptophan synthesis. AD013 has the potential to provide potent anti-hypertensive and cardioprotective effects. Target: Others

MW:

424.49 D

ab 1.440,00 €

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CDK8-IN-11 hydrochloride

Artikelnummer: TGM-T62293-100mg

Description: CDK8-IN-11 hydrochloride is a selective and potent inhibitor of CDK8 (IC50: 46 nM) that inhibits the WNT/beta-catenin signaling pathway and can be utilized for studying colon cancer. Target: Others

MW:

424.8 D

ab 1.440,00 €

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MEIS-IN-2

Artikelnummer: TGM-T62295-100mg

Description: MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation. Target: Others

MW:

424.88 D

ab 1.440,00 €

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HIV-1 inhibitor-44

Artikelnummer: TGM-T62319-100mg

Description: HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor with activity against wild-type HIV-1 strains (EC50: 0.209 µM). Target: Others

MW:

426.53 D

ab 1.440,00 €

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CXCR7 antagonist-1 hydrochloride

Artikelnummer: TGM-T62325-25mg

Description: CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of SDF-1 chemokine (also known as CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. Hydrochloride can be used for the prevention of tumor cell proliferation, tumor formation, inflammatory...

MW:

426.87 D

ab 1.488,00 €

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HDAC2-IN-1

Artikelnummer: TGM-T62327-100mg

Description: HDAC2-IN-1 (Compound 17) is an orally active, competitive HDAC2 inhibitor (IC50: 0.5 µM) that crosses the blood-brain barrier and also inhibits HDAC1 (IC50: 1.61 µM) and HDAC8 (IC50: 0.98 µM). Target: Others

MW:

426.96 D

ab 1.440,00 €

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Autophagy-IN-1

Artikelnummer: TGM-T62331-100mg

Description: Autophagy-IN-1 is a potent inhibitor of autophagy/mitophagy that blocks autophagosomal-lysosomal fusion in cancer cells while selectively increasing autophagic flux. It significantly inhibits tumor growth in the HCT116 mouse xenograft tumour model with low toxicity and can be used to study colorectal...

MW:

427.45 D

ab 1.440,00 €

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