Produkte von South Bay Bio
South Bay Bio ist ein Biotechnologieunternehmen, das sich auf die Herstellung von Hochdurchsatz-Screening-Produkten mit Schwerpunkt auf dem Ubiquitin-Proteasom-System spezialisiert hat. Das Unternehmen wurde in der San Francisco Bay Area gegründet, um dort ansässige Biotechnologie-Unternehmen zu unterstützen. Der Firmensitz befindet sich in San José, Kalifornien.
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![Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC]](https://www.biomol.com/media/image/27/5d/ea/SBB-PS0008-M002_200x200.png "Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC]")
Ac-Trp-Leu-Ala-AMC [Ac-WLA-AMC]
Artikelnummer: SBB-PS0008-M002
Lyophilized powder. Soluble in DMSO. Ac-WLA-AMC is a fluorogenic peptid substrate for measuring chymotrypsin-like activity of the proteasome. Hydrolysis of this substrate by the beta5-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
| Schlagworte: | Proteasome Substrate |
| Anwendung: | Fluorogenic peptide substrate |
| MW: | 587,7 D |
237,00 €
Ubiquitin (human) (rec.) (Europium-Cryptate)
Artikelnummer: SBB-TR0014-C020
Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the...
| Schlagworte: | UBB, Ubiquitin B |
| Anwendung: | Assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 10 kD |
5.097,00 €
TRF-Ubiquitin Mix (100X) (2000 reactions)
Artikelnummer: SBB-TR0051-2K-1
Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the...
| Schlagworte: | TRF-Ub Mix, UBB |
| Anwendung: | Ubiquitination studies |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 8.5-8.9 kD |
6.103,00 €
![Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)](https://www.biomol.com/media/image/84/ec/2d/SBB-CE0058-C050_200x200.png "Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)")
Ubiquitin Activating Enzyme E1 [UBA1] (human) (rec.) (His)
Artikelnummer: SBB-CE0058-C050
Protein. Human UBA1 (aa12-1058) is fused at the N-terminus to a His-tag. Source: Sf21 cells. Liquid. In 50mM HEPES pH 7.5, 150mM sodium chloride, 10% glycerol, 2mM TCEP. Purity: >95% (SDS-PAGE). UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and...
| Schlagworte: | Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2 |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 120 kD |
338,00 €
Cullin4a/Rbx1/DDB1/CRBN E3 Ligase Complex TR-FRET Kit
Artikelnummer: SBB-KF0120-KI01
South Bay Bio's Cullin4a/Rbx1/DDB1/CRBN Neddylated E3 Ligase TR-FRET Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto the E3 complex in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET...
| Schlagworte: | CUL4A, CUL-4A, Cullin-4A |
| Anwendung: | Compound Screening |
| Spezies-Reaktivität: | human |
1.451,00 €
HA-Ubiquitin-vinyl methyl ester (human) (rec.) (HA)
Artikelnummer: SBB-PS0123-C050
Protein. Human ubiquitin (aa1-76) (Accession Nr. P0CG47) with a C-terminal vinyl methyl ester group and a N-terminal HA-Tag. Source: E. coli. Liquid. In 50mM MES pH 6.0, 100mM sodium chloride. Purity: >97% (LCMS). Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of...
| Schlagworte: | HA-Ub-VME, HA-Ubiquitin-VME, HA-Ubiquitin-Vinyl methyl ester |
| Exprimiert in: | E. coli |
| Ursprungsart: | human |
| MW: | 10 kD |
425,00 €
![UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)](https://www.biomol.com/media/image/5f/ea/64/SBB-CE0022-C100_200x200.png "UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)")
UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)
Artikelnummer: SBB-CE0022-C100
UBE2K (UbcH1) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2K via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2K-Ub thioester. UBE2K is capable of...
| Schlagworte: | Ubiquitin-conjugating Enzyme E2, E2-25K, Hip2, HYPG, LIG, UBE2K, UBE2K-25K, Huntingtin-interacting Protein 2 |
| Anwendung: | Assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 22 kD |
402,00 €
![UbcH5b [UBE2D2] (human) (rec.) (untagged)](https://www.biomol.com/media/image/0d/6f/b3/SBB-CE0027-C100_200x200.png "UbcH5b [UBE2D2] (human) (rec.) (untagged)")
UbcH5b [UBE2D2] (human) (rec.) (untagged)
Artikelnummer: SBB-CE0027-C100
UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D2-Ub thioester. UBE2D2 is capable of...
| Schlagworte: | Ubiquitin-conjugating Enzyme H5b, PUBC1, UBC5B, Ubiquitin-protein Ligase D2, p53-regulated Ubiquitin-conjugating Enzyme 1 |
| Anwendung: | Assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 17 kD |
402,00 €
UcH-L3 (human) (rec.) (untagged)
Artikelnummer: SBB-DE0023-C050
UCHL3 (Ubiquitin C-terminal Hydrolase L3) is a deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. It is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8....
| Schlagworte: | Ubiquitin C-terminal Hydrolase L3, Ubiquitin Thioesterase L3 |
| Anwendung: | Assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 26 kD |
323,00 €
![NEDP1 [SENP8] (human) (rec.) (His)](https://www.biomol.com/media/image/df/17/95/SBB-DE0025-C050_200x200.png "NEDP1 [SENP8] (human) (rec.) (His)")
NEDP1 [SENP8] (human) (rec.) (His)
Artikelnummer: SBB-DE0025-C050
NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which hydrolyzes the isopeptide bond between the C-terminus of NEDD8 and the respective lysine of the substrate...
| Schlagworte: | NEDD8-specific Protease 1, Sentrin-specific Protease 8, Deneddylase-1, Sentrin/SUMO-specific Protease SENP8, DEN1, PRSC2 |
| Anwendung: | Assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 27 kD |
281,00 €
SENP1 (catalytic domain) (human) (rec.) (His)
Artikelnummer: SBB-DE0026-C050
SUMO/Sentrin Specific Peptidase 1 (SENP1) is a member of the SENP family of proteases, which belong to the group of cysteine-type peptidases. SENP1 is a SUMO-specific enzyme that catalyzes two essential functions. Processing the full-length versions of SUMO1, SUMO2 and SUMO3 into its mature forms and the...
| Schlagworte: | Sentrin-specific Protease 1, Sentrin/SUMO-specific Protease SENP1 |
| Anwendung: | Assays |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 32 kD |
318,00 €
Parkin E3 Ligase TR-FRET Kit
Artikelnummer: SBB-KF0036-KI01
South Bay Bio's Parkin TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto both wild-type Parkin and a more active mutant W403A in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous...
| Schlagworte: | PRKN, PARK2, Parkin, Parkinson disease protein 2, E3 ubiquitin-protein ligase parkin, Parkinson juvenile disease protein 2 |
| Anwendung: | Enzyme assays |
| Spezies-Reaktivität: | human |
1.451,00 €