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Zu "Q9UGN5" wurden 41 Artikel gefunden!
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NEU
Artikelnummer: BBL-2347
Active, full-length human PARP2 (AA 1-583) protein expressed and purified from Baculovirus infected insect cells with an N-Terminal His tag. The enzyme has been thoroughly validated with the Transcreener pADPr Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme...
| Schlagworte: | PARP2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2, NAD(+) ADP-ribosyltransferase 2, DNA... |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
ab 569,00 €
NEU
Artikelnummer: BBL-3050-10K-FP
The Enzolution(R) PARP2 Assay System is intended for use with the Transcreener(R) pADPr PARP Assay Kits (Parts #3043 and #3044) to measure the enzymatic activity of PARP2 (poly(ADP-ribose)polymerase 2). Upon binding to DNA, PARP2 forms poly(ADP-ribose) (pADPr) chains on target proteins, including itself, using NAD+...
| Schlagworte: | PARP2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2, NAD(+) ADP-ribosyltransferase 2, DNA... |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 808,00 €
NEU
Artikelnummer: BBL-3050-10K-TR
The Enzolution(R) PARP2 Assay System is intended for use with the Transcreener(R) pADPr PARP Assay Kits (Parts #3043 and #3044) to measure the enzymatic activity of PARP2 (poly(ADP-ribose)polymerase 2). Upon binding to DNA, PARP2 forms poly(ADP-ribose) (pADPr) chains on target proteins, including itself, using NAD+...
| Schlagworte: | PARP2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2, NAD(+) ADP-ribosyltransferase 2, DNA... |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 854,00 €
Artikelnummer: BPS-80502
Active human PARP2 (GenBank Accession No. NM_005484), amino-acids 2-583 with N-terminal GST tag, MW = 92 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | ARTD2, PARP-2, ADPRT2, ADPRT-2, hPARP-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2, NAD(+)... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 92 kD |
879,00 €
Artikelnummer: ARG57124.50
Protein function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism (PubMed:10364231, PubMed:28190768). This modification follows DNA damages and appears as an obligatory step...
| Schlagworte: | Anti-PARP2, Anti-ARTD2, Anti-ADPRT2, Anti-PARP-2, Anti-ADPRT-2, Anti-hPARP-2, Anti-pADPRT-2, EC=2.4.2.30,... |
| Anwendung: | WB, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
518,00 €
Artikelnummer: ARG63904.100
Protein function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway...
| Schlagworte: | Anti-ARTD2, Anti-PARP2, Anti-PARP-2, Anti-ADPRT2, Anti-ADPRT-2, Anti-hPARP-2, Anti-pADPRT-2, EC=2.4.2.30,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Artikelnummer: BPS-80581
The PARP2 Colorimetric Activity Assay Kit is designed to measure PARP2 activity for screening and profiling applications. PARP2 is known to catalyze the NADdependent addition of poly(ADP-ribose) to histones. The key to the PARP2 Colorimetric Activity Assay is the biotinylated substrate. With this kit, only three...
| Schlagworte: | poly(ADP-ribose)polymerase 2, poly(ADP-ribosyl)transferase 2, ADPRT, PARP2, |
| Anwendung: | Studying enzyme kinetics, screening small molecular inhibitors for drug discovery, HTS applications |
| Spezies-Reaktivität: | human |
1.373,00 €
Artikelnummer: G-HUFI02172.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: NSJ-R34712-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Poly (ADP-ribose) polymerase family, member 2 Protein function: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor...
| Schlagworte: | Anti-ARTD2, Anti-PARP2, Anti-PARP-2, Anti-ADPRT2, Anti-hPARP-2, Anti-ADPRT-2, Anti-pADPRT-2, EC=2.4.2.30,... |
| Anwendung: | WB, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Artikelnummer: ARG42604.100
Protein function: Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:28190768, PubMed:25043379). Mainly mediates glutamate and aspartate ADP-ribosylation of target proteins: the ADP-D- ribosyl group of NAD(+) is transferred to the...
| Schlagworte: | Anti-ARTD2, Anti-PARP2, Anti-ADPRT2, Anti-PARP-2, Anti-hPARP-2, Anti-ADPRT-2, Anti-pADPRT-2, Anti-Poly[ADP-ribose]... |
| Anwendung: | FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Artikelnummer: Cay32562-10
Poly(ADP-Ribose) polymerase 2 (PARP2) is an ADP-ribosylating enzyme with a role in the DNA damage response (DRR). It is composed of a natively disordered N-terminal region containing a nuclear localization sequence, a central Trp-Gly-Arg (WGR) domain that is essential to DNA damage-dependent catalytic domain...
| Schlagworte: | PARP2, ARTD2, ARTD2, ADPRT2, PARP-2, PARP-2, hPARP-2, ADPRT-2, hPARP-2, ADPRT-2, pADPRT-2, pADPRT-2, Poly[ADP-ribose]... |
| Anwendung: | Enzyme assay |
| Exprimiert in: | Insect cells |
867,00 €
Artikelnummer: BPS-78296-1
The PARPtrap(TM) Assay Kit for PARP2 is designed to measure PARP2/DNA complex formation in a high throughput screening assay using fluorescence polarization (FP). Similarly, to PARP1, PARP2 recognizes and binds damaged DNA via its DNA-binding domain. Binding to DNA activates PARP2 and in the presence of NAD+ PARP2...
| Schlagworte: | ARTD2, PARP-2, ADPRT2, ADPRT-2, hPARP-2, pADPRT-2, Poly[ADP-ribose] synthase 2, Poly [ADP-ribose] polymerase 2, NAD(+)... |
| Anwendung: | Small molecule screening, drug discovery, HTS, IC50 determination |
| Spezies-Reaktivität: | human |
ab 2.992,00 €