Zu "Q96SW2" wurden 45 Artikel gefunden!
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CRBNmidi (human, recombinant)
Artikelnummer: Cay45179-10
Source: Recombinant human N-terminal His-tagged CRBNmidi expressed in E. coli Amino acids: 41-187-GSG-249-426 MW: 39.8 kDa. SMILES: . InChi Code: . InChi Key:
| Schlagworte: | Cereblonmidi |
| Exprimiert in: | E. coli |
ab 345,00 €
Anti-CRBN / Cereblon
Artikelnummer: NSJ-FY12446
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. CRBN antibody recognizes Cereblon, a substrate receptor component of the CRL4 E3 ubiquitin ligase complex that plays a central role in targeted protein degradation. Cereblon binds to the DDB1-CUL4-ROC1 complex, recruiting specific substrates...
| Schlagworte: | Anti-CRBN, Anti-Protein cereblon, CRBN Antibody / Cereblon |
| Anwendung: | WB, ICC/IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Cereblon Binding Assay Kit
Artikelnummer: BPS-79899
The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN. CRBN is the substrate recognition...
| Schlagworte: | CRBN, AD-006, Protein cereblon |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.482,00 €
Protein cereblon (CRBN), partial, Biotinylated, human,...
Artikelnummer: CSB-EP842761HU1-B.20
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 318-426aa. Protein Length: Partial. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged. Target Protein Sequence: CTSLCCKQCQ ETEITTKNEI FSLSLCGPMA AYVNPHGYVH ETLTVYKACN LNLIGRPSTE HSWFPGYAWT VAQCKICASH IGWKFTATKK DMSPQKFWGL TRSALLPTI....
| Schlagworte: | CRBN, AD-006, Protein cereblon, Recombinant Human Protein cereblon (CRBN), partial, Biotinylated |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 59.9 kD |
ab 439,00 €
Cereblon/DDB1/Cul4A/Rbx1 Complex
Artikelnummer: BPS-100329-1
Cereblon/DDB1/Cul4A/Rbx1 complex of human Cereblon (GenBank Accession No. NM_016302) a.a. 2-442(end) with N-terminal FLAG-tag and MW= 51 kDa, human DDB1 (GenBank Accession No. NM_001923), a.a. 1-1140(end) with N-terminal FLAG-tag and MW= 128 kDa, human Cul4A (GenBank Accession No. NM_003589), a.a. 2-759(end) with...
| Schlagworte: | CRBN, AD-006, Protein cereblon, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | human cells |
| Ursprungsart: | human |
| MW: | 51/128/87... kD |
ab 386,00 €
Cereblon Ubiquitination Homogeneous Assay Kit
Artikelnummer: BPS-79881
The Cereblon Ubiquitination Homogeneous Assay Kit is designed to measure Cereblon auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled ubiquitin and proper A-screen beads to complete the pairing. This homogeneous assay requires no time-consuming washing steps, making it...
| Schlagworte: | CRBN, AD-006, Protein cereblon |
| Anwendung: | Small molecular inhibitor/PROTAC screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.285,00 €
Human CRBN / Protein cereblon ELISA Kit
Artikelnummer: G-HUFI01180.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-CRBN
Artikelnummer: 600-401-AN1
Anti-CRBN antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. CRBN antibody is human, mouse and rat reactive. At least two isoforms of CRBN are known to exist, this antibody will detect both isoforms. Protein function: Substrate recognition component of a DCX (DDB1-CUL4-X-...
| Schlagworte: | Anti-CRBN, Anti-AD-006, Anti-Protein cereblon |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding
Artikelnummer: BPS-79770
The PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding is designed for testing and profiling of PROTACs directed against BET Bromodomain family and Cereblon complex. Cereblon (CRBN) is a Substrate recognition component of a DCX (DDB1-CUL44-Rbx1) E3 protein ligase complex that mediates the ubiquitination...
| Schlagworte: | CRBN, Protein X 0001, MRT2A MRT2, |
| Anwendung: | Protac |
| Spezies-Reaktivität: | human |
1.555,00 €
Anti-CRBN
Artikelnummer: ARG59917.100
Protein function: Substrate recognition component of a DCX (DDB1-CUL4-X- box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as MEIS2. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the...
| Schlagworte: | Anti-CRBN, Anti-AD-006, Anti-Protein cereblon |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
PROTAC Optimization Kit for CDK Kinase-Cereblon Binding
Artikelnummer: BPS-79924
The PROTAC Optimization Kit for CDK Kinase-Cereblon Binding is designed for testing and profiling of PROTACs directed against the CDK Kinase family and Cereblon. Cereblon (CRBN) is a Substrate recognition component of the DCX (DDB1-CUL44-Rbx1) E3 protein ligase complex that mediates the ubiquitination and subsequent...
| Schlagworte: | CRBN, AD-006, Protein cereblon |
| Anwendung: | PROTAC optimization |
| Spezies-Reaktivität: | human |
2.914,00 €
Cereblon intrachain TR-FRET Assay Kit
Artikelnummer: BPS-78301
Covalent conjugation to ubiquitin (Ub) is one of the major post-translational modifications that regulates protein stability, function, and localization. Ubiquitination is the concerted action of three enzymes: a Ub-activating enzyme (E1), a Ub-conjugating enzyme (E2), and a Ub ligase (E3). The specificity and...
| Schlagworte: | CRBN, MRT2A, MRT2, TR-FRET Kit, Homogeneous Kit, |
| Anwendung: | Small molecule screening, drug discovery, HTS, kinetics |
| Spezies-Reaktivität: | human |
2.632,00 €