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NEU
Recombinant SIRT1 Enzyme, Active, Human
Recombinant SIRT1 Enzyme, Active, Human

Artikelnummer: BBL-2340

Active, full-length human SIRT1 (AA 1-747) protein expressed and purified from Baculovirus infected insect cells with a C-Terminal His tag. The enzyme has been thoroughly validated with the Transcreener OAADPr Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme...
Schlagworte: SIRT1, SIR2-like protein 1, Regulatory protein SIR2 homolog 1, NAD-dependent protein deacylase sirtuin-1, NAD-dependent...
Anwendung: HTS, drug discovery, enzyme assays
Exprimiert in: Insect cells
Ursprungsart: human
ab 341,00 €
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NEU
Enzolution(R) SIRT1 FP Assay System
Enzolution(R) SIRT1 FP Assay System

Artikelnummer: BBL-3048-10K-FP

The Enzolution(R) SIRT1 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT1 (NAD-dependent protein deacetylase sirtuin 1). SIRT1 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...
Schlagworte: SIRT1, SIR2-like protein 1, Regulatory protein SIR2 homolog 1, NAD-dependent protein deacylase sirtuin-1, NAD-dependent...
Anwendung: HTS, drug discovery, enzyme assays
ab 603,00 €
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NEU
Enzolution(R) SIRT1 TR-FRET Assay System
Enzolution(R) SIRT1 TR-FRET Assay System

Artikelnummer: BBL-3048-10K-TR

The Enzolution(R) SIRT1 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT1 (NAD-dependent protein deacetylase sirtuin 1). SIRT1 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...
Schlagworte: SIRT1, SIR2-like protein 1, Regulatory protein SIR2 homolog 1, NAD-dependent protein deacylase sirtuin-1, NAD-dependent...
Anwendung: HTS, drug discovery, enzyme assays
ab 637,00 €
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Human SIRT1 (Sirtuin 1) Microsample ELISA Kit
Human SIRT1 (Sirtuin 1) Microsample ELISA Kit

Artikelnummer: ELK-ELK10541MS.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SIRT1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SIRT1. Next,...
Schlagworte: SIRT1, SIR2-like protein 1, Regulatory protein SIR2 homolog 1, NAD-dependent protein deacylase sirtuin-1, NAD-dependent...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 374,00 €
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Anti-phospho-SIRT1 (pSer47) / Sirtuin 1, clone FDA-19
Anti-phospho-SIRT1 (pSer47) / Sirtuin 1, clone FDA-19

Artikelnummer: NSJ-FY13408

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Sirtuin 1 (SIRT1) is a NAD-dependent deacetylase involved in regulation of chromatin organization, metabolic adaptation, oxidative stress signaling, and cellular survival pathways. Phospho-SIRT1...
Schlagworte: Anti-phospho-SIRT1, Anti-phospho-SIR2-like protein 1, Anti-phospho-Regulatory protein SIR2 homolog 1,...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
790,00 €
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Anti-phospho-SIRT1 (pThr530), clone HAI-19
Anti-phospho-SIRT1 (pThr530), clone HAI-19

Artikelnummer: NSJ-FY13407

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Sirtuin 1 (SIRT1) is a NAD-dependent protein deacetylase involved in regulation of metabolic adaptation, chromatin signaling, oxidative stress responses, and cellular survival pathways. Phospho-SIRT1...
Schlagworte: Anti-phospho-SIRT1, Anti-phospho-SIR2-like protein 1, Anti-phospho-Regulatory protein SIR2 homolog 1,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
790,00 €
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SIRT1 Direct Fluorescent Screening Assay Kit
SIRT1 Direct Fluorescent Screening Assay Kit

Artikelnummer: Cay10010401-96

Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Schlagworte: SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1
Anwendung: SIRT1 inhibitor/activator screening
Spezies-Reaktivität: human
533,00 €
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Fluorogenic SIRT1 (Sir2) Assay Kit
Fluorogenic SIRT1 (Sir2) Assay Kit

Artikelnummer: BPS-50081

The Fluorogenic SIRT1 Assay Kit is a complete assay system designed to measure Sirtuin 1 (SIRT1) activity for screening and profiling Applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent SIRT1 (Sir2) activity measurements. In addition, the kit includes purified...
Schlagworte: SIR2L1,
Anwendung: Enzyme kinetics, inhibitor screening, HTS
700,00 €
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Sirtuin 1, active human recombinant protein
Sirtuin 1, active human recombinant protein

Artikelnummer: BPS-50012

Active human Sirtuin 1 , GenBank Accession No. NM_012238), amino acids 193- 741 with N-terminal GST tag, MW= 87.2 kDa, expressed in E. coli expression system.
Schlagworte: SIR2L1,
Anwendung: Enzyme kinetics, inhibitor screening
MW: 87.2 kD
663,00 €
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SIRT1 (human, recombinant)
SIRT1 (human, recombinant)

Artikelnummer: Cay10011190-100

The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
Schlagworte: hSIR2, SIR2L1, hSIRT1, 75SirT1, SIR2-like protein 1, SirtT1 75 kDa fragment, Regulatory protein SIR2 homolog 1,...
Anwendung: Enzyme activity
MW: 89,2 kD
734,00 €
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SIRT1 FRET-Based Screening Assay Kit
SIRT1 FRET-Based Screening Assay Kit

Artikelnummer: Cay10010991-96

Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Sir2 (Silent information regulator 2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
Schlagworte: SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1
Anwendung: SIRT1 inhibitor/activator screening
Spezies-Reaktivität: human
533,00 €
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Anti-Sirt1
Anti-Sirt1

Artikelnummer: A300-687A

Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function...
Schlagworte: Anti-SIRT1, Anti-SIR2L1, EC=3.5.1.-
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human
ab 165,00 €
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