Zu "Q96EB6" wurden 104 Artikel gefunden!
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SIRT1 Direct Fluorescent Screening Assay Kit
Artikelnummer: Cay10010401-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Silent information regulator 2 (Sir2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Schlagworte: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
| Anwendung: | SIRT1 inhibitor/activator screening |
| Spezies-Reaktivität: | human |
516,00 €
Anti-SIRT1 Monoclonal Antibody
Artikelnummer: E-AN200054P.100
SIRT1 (SIR2-like protein 1, also NAD-dependent protein deacetylase sirtuin-1 and hSIR2) is a class I member of the sirtuin family of enzymes. Although its predicted MW is 81 kDa, it runs anomalously at 110-120 kDa in SDS-PAGE. It is a widely expressed nuclear protein that participates in the deacetylation of...
| Schlagworte: | SIR2L1, SIRT1 Monoclonal Antibody |
| Anwendung: | IHC (paraffin), ICC/IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
Fluorogenic SIRT1 (Sir2) Assay Kit
Artikelnummer: BPS-50081
The Fluorogenic SIRT1 Assay Kit is a complete assay system designed to measure Sirtuin 1 (SIRT1) activity for screening and profiling Applications. It comes in a convenient 96-well format, with all the reagents necessary for 100 fluorescent SIRT1 (Sir2) activity measurements. In addition, the kit includes purified...
| Schlagworte: | SIR2L1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, HTS |
700,00 €
Sirtuin 1, active human recombinant protein
Artikelnummer: BPS-50012
Active human Sirtuin 1 , GenBank Accession No. NM_012238), amino acids 193- 741 with N-terminal GST tag, MW= 87.2 kDa, expressed in E. coli expression system.
| Schlagworte: | SIR2L1, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 87.2 kD |
663,00 €
SIRT1 (human, recombinant)
Artikelnummer: Cay10011190-100
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group. There are seven human sirtuins,...
| Schlagworte: | hSIR2, SIR2L1, hSIRT1, 75SirT1, SIR2-like protein 1, SirtT1 75 kDa fragment, Regulatory protein SIR2 homolog 1,... |
| Anwendung: | Enzyme activity |
| MW: | 89,2 kD |
712,00 €
Anti-phospho-SIRT1 (Ser47)
Artikelnummer: CSB-PA857953.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy (PubMed:11672523,...
| Schlagworte: | Anti-phospho-SIR2L1, Phospho-SIRT1 (Ser47) Antibody |
| Anwendung: | ELISA, WB |
| Spezies-Reaktivität: | human |
340,00 €
SIRT1 FRET-Based Screening Assay Kit
Artikelnummer: Cay10010991-96
Sirtuins (SIRTs) represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs). Human SIRT1 is the homolog of yeast Sir2 (Silent information regulator 2) and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Small molecule activators of SIRT1,...
| Schlagworte: | SIRT1, hSIR2, hSIRT1, SIR2L1, EC=3.5.1.-, SIR2-like protein 1, NAD-dependent deacetylase sirtuin-1 |
| Anwendung: | SIRT1 inhibitor/activator screening |
| Spezies-Reaktivität: | human |
516,00 €
Anti-Sirt1
Artikelnummer: A300-687A
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function...
| Schlagworte: | Anti-SIRT1, Anti-SIR2L1, EC=3.5.1.- |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-Sirtuin 1 (human)
Artikelnummer: AG-25A-0082-C100
Recognizes human sirtuin 1. Detects a band of about 78kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-1 is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. Sirtuin-1...
| Schlagworte: | SIRT1, NAD-dependent Deacetylase Sirtuin-1, SIR2-like Protein 1, SIR2L1 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
286,00 €
Anti-SIRT1, clone 2G10-F4-D9
Artikelnummer: ARG54170.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function...
| Schlagworte: | Anti-SIRT1, Anti-SIR2L1, EC=3.5.1.- |
| Anwendung: | WB, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Anti-SIRT1
Artikelnummer: ARG54682.50
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function...
| Schlagworte: | Anti-SIRT1, Anti-SIR2L1, EC=3.5.1.- |
| Anwendung: | ELISA, WB, ICC, IF |
| Wirt: | Chicken |
| Spezies-Reaktivität: | human, mouse, rat |
625,00 €
Anti-SIRT1
Artikelnummer: ARG55039.100
Protein function: NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function...
| Schlagworte: | Anti-SIRT1, Anti-SIR2L1, EC=3.5.1.- |
| Anwendung: | WB, IHC, ICC, IF, IP, ChIP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
707,00 €