Zu "Q92574" wurden 56 Artikel gefunden!
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Anti-Recombinant Hamartin, clone A773
Artikelnummer: E-AN302053L.100
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that causes symptoms including hamartomas in brain, kidney, heart, lung and skin. The tumor suppressor genes TSC1 and TSC2 encode hamartin and tuberin, respectively. Hamartin and tuberin form a functional complex and are involved in numerous cellular...
| Schlagworte: | Anti-TSC1, Anti-Hamartin, Anti-Tuberous sclerosis 1 protein, Recombinant Hamartin Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat, mouse |
ab 304,00 €
Anti-TSC1
Artikelnummer: ATA-HPA069758.100
Rabbit Polyclonal TSC1 Antibody against Human TSC complex subunit 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000026812: 95%, ENSRNOG00000011470:...
| Schlagworte: | Anti-TSC1, Anti-KIAA0243, Anti-Hamartin, Anti-Tuberous sclerosis 1 protein |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 264,00 €
Anti-TSC1
Artikelnummer: A300-316A
Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein...
| Schlagworte: | Anti-TSC1, Anti-Hamartin, Anti-KIAA0243, Anti-Tuberous sclerosis 1 protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-Hamartin / TSC1 (isoform 1), C-terminal
Artikelnummer: ARG63935.100
Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein...
| Schlagworte: | Anti-TSC1, Anti-KIAA0243, Anti-Hamartin, Anti-Tuberous sclerosis 1 protein |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-TSC1 (Hamartin)
Artikelnummer: NSJ-R31119
0.5mg/ml if reconstituted with 0.2ml sterile DI water. TSC1 (Tuberous Sclerosis 1), also called Hamartin, is a human protein and gene. As part of a comprehensive strategy to identify the gene mutant in tuberous sclerosis-1, van Slegtenhorst et al.(1997) developed an overlapping contig of clones from the 1.4-Mb TSC1...
| Schlagworte: | Anti-TSC1, Anti-Hamartin, Anti-KIAA0243, Anti-Tuberous sclerosis 1 protein, TSC1 Antibody (Hamartin) |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-Hamartin
Artikelnummer: NSJ-R31542
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Hamartin, also known as Tuberous sclerosis 1, is a protein that in humans is encoded by the TSC1 gene. It is mapped to 9q34.13. This peripheral membrane protein was implicated as a tumor suppressor. It forms a complex with TSC2 that regulates mTORC1 signaling...
| Schlagworte: | Anti-TSC1, Anti-Hamartin, Anti-KIAA0243, Anti-Tuberous sclerosis 1 protein, Hamartin Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
Anti-TSC1
Artikelnummer: NSJ-R35353-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Tuberous sclerosis 1, Hamartin Protein function: In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating...
| Schlagworte: | Anti-TSC1, Anti-Hamartin, Anti-KIAA0243, Anti-Tuberous sclerosis 1 protein, TSC1 Antibody |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-phospho-TSC1 (Ser505)
Artikelnummer: NSJ-F48536-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. TSC1 is implicated as a tumor suppressor, and may have a function in vesicular transport. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Defects in TSC1 are the cause of tuberous sclerosis complex (TSC). The molecular basis of TSC is a functional...
| Schlagworte: | Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-KIAA0243, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1... |
| Anwendung: | Dot Blot, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-TSC1 (Thr310)
Artikelnummer: NSJ-F48811-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
| Schlagworte: | Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1 Antibody (pT310) |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-TSC1 (Tyr304)
Artikelnummer: NSJ-F48831-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. Protein function: In complex with TSC2,...
| Schlagworte: | Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-KIAA0243, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1... |
| Anwendung: | Dot Blot, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-TSC1 (Tyr312)
Artikelnummer: NSJ-F48832-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. Protein function: In complex with TSC2,...
| Schlagworte: | Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-KIAA0243, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1... |
| Anwendung: | Dot Blot, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-phospho-TSC1 (Ser1080)
Artikelnummer: NSJ-F48827-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.
| Schlagworte: | Anti-phospho-TSC1, Anti-phospho-Hamartin, Anti-phospho-Tuberous sclerosis 1 protein, Phospho-TSC1 Antibody (pS1080) |
| Anwendung: | DB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €