Zu "Q86Z14" wurden 28 Artikel gefunden!
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NEU
Beta Klotho Protein, Human, Recombinant (aa 53-983, His)
Artikelnummer: TGM-TMPY-06989-100ug
Description: Beta Klotho Protein, Human, Recombinant (aa 53-983, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 108.53 kDa and the accession number is Q86Z14.
| Schlagworte: | Beta-klotho , BetaKlotho , BKL , KLB , Klotho beta-like protein |
| MW: | 108.53 kD |
ab 75,00 €
Human Klotho beta ELISA Kit
Artikelnummer: ARG81934.96
Protein function: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21. [The UniProt Consortium]
| Schlagworte: | KLB, BKL, BetaKlotho, Beta-klotho, Klotho beta-like protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.151,00 €
Human Klotho beta / KLB ELISA Kit
Artikelnummer: G-HUFI00859.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
![FGFR/beta-Klotho Reporter Assay System [Human]](https://www.biomol.com/media/image/78/af/99/IB-IB22002_200x200.png "FGFR/beta-Klotho Reporter Assay System [Human]")
FGFR/beta-Klotho Reporter Assay System [Human]
Artikelnummer: IB-IB22002
The family of Fibroblast Growth Factors (FGFs) comprise approximately 23 members that are related by core sequence and structure conservation, with the majority of FGFs being secreted signaling proteins. Secreted FGFs are predominantly autocrine and paracrine factors, with only three members evolved to function as...
| Schlagworte: | Fibroblast Growth Factor Receptor 1c , FGFR1c/beta-Klotho, BKL, KLB, BetaKlotho, Beta-klotho, Klotho beta-like protein,... |
| Anwendung: | Functional activity screening, For endocrine FGF Signaling |
| Spezies-Reaktivität: | human |
4.175,00 €
Human KLb (Klotho Beta) ELISA Kit
Artikelnummer: ELK-ELK3813.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KLb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KLb. Next,...
| Schlagworte: | BKL, KLB, BetaKlotho, Beta-klotho, Klotho beta-like protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Beta Klotho Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPK-01078-100ug
Description: Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but...
| Schlagworte: | Klotho beta, klotho beta like, beta Klotho, betaKlotho, MGC142213, beta-klotho, betaKlotho, BKL, Klotho beta, beta-klotho,... |
| MW: | 111.6 kD |
ab 1.535,00 €
NEU
Beta Klotho Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPK-01078-10ug
Description: Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but...
| Schlagworte: | betaKlotho , Klotho beta , beta-klotho , MGC142213 , betaKlotho , BKL , beta-klotho , KLB , klotho beta like , beta Klotho... |
| MW: | 111.6 kD |
ab 161,00 €
Human KLb (Klotho Beta) ELISA Kit
Artikelnummer: G-AEKE07966.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human KLb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human KLb. Next,...
| Schlagworte: | KLB, Beta-klotho, Klotho beta-like protein |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Efruxifermin
Artikelnummer: BPS-83939-1
Efruxifermin, also known as AKR-001 or AMG-876, is an fusion protein composed of human IgG1 Fc domain linked to a modified human FGF21. Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis...
| Schlagworte: | KLB, Beta-klotho, Klotho beta-like protein |
| Anwendung: | Cellular assays |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 2375240-92-7 |
| MW: | 91.8 kD |
ab 1.542,00 €
FGFR/beta-Klotho Reporter Assay System [Human]
Artikelnummer: IB-IB22001
The family of Fibroblast Growth Factors (FGFs) comprise approximately 23 members that are related by core sequence and structure conservation, with the majority of FGFs being secreted signaling proteins. Secreted FGFs are predominantly autocrine and paracrine factors, with only three members evolved to function as...
| Schlagworte: | Fibroblast Growth Factor Receptor 1c , FGFR1c/beta-Klotho, BKL, KLB, BetaKlotho, Beta-klotho, Klotho beta-like protein,... |
| Anwendung: | Functional activity screening, for endocrine FGF Signaling |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
FGF-21 Responsive Luciferase Reporter HEK293 Cell Line
Artikelnummer: BPS-83572
The FGF-21 Responsive Luciferase Reporter HEK293 Cell Line is a HEK293 cell line engineered to express firefly luciferase under the control of the GAL4 upstream activation sequence (UAS). It overexpresses human beta-Klotho (KLB, NM_175737.4) and human Elk-1 (ETS Like-1 protein) transactivation domain (Elk1-TA, amino...
| Schlagworte: | KLB, Beta-klotho, Klotho beta-like protein, Fibroblast growth factor 21, FGF21, UNQ3115, PRO10196, beta-Klotho, KLB, |
| Anwendung: | Analog/antagonist screening |
| Spezies-Reaktivität: | human |
9.897,00 €
Human Beta-klotho (KLB) ELISA kit
Artikelnummer: CSB-EL012378HU.48
Sample Types: serum, plasma, tissue homogenates, cell lysates Detection Range: 62.5 pg/mL-4000 pg/mL Sensitivity: 15.6 pg/mL Assay Principle: quantitative Measurement: SandwichAssay Time: 1-5h Sample Volume: 50-100ulDetection Wavelength: 450 nmProtein function: Contributes to the transcriptional repression of...
| Schlagworte: | BKL, KLB, BetaKlotho, Beta-klotho, Klotho beta-like protein |
| Anwendung: | ELISA, Sandwich ELISA |
| Spezies-Reaktivität: | human |
ab 501,00 €