Zu "Q00987" wurden 101 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
MDM2-Driven p53 Ubiquitination Assay Kit
Artikelnummer: BPS-82179
The MDM2-Driven p53 Ubiquitination Assay kit is a sensitive AlphaLisa(R) high-throughput screening (HTS) assay designed to measure MDM2 (mouse double minute 2 homolog) E3 ligase activity in a homogeneous 384 reaction format. The assay kit comes with enough biotinylated ubiquitin, ATP, FLAG-tagged p53, assay buffer,...
| Schlagworte: | Hdm2, MDM2, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase Mdm2,... |
| Anwendung: | Inhibitor screening, drug discovery, HTS, IC50 determination, MDM2-driven ubiquitination studies |
| Spezies-Reaktivität: | human |
2.518,00 €
Human E3 ubiquitin-protein ligase Mdm2,MDM2 ELISA kit
Artikelnummer: ELK-ELK8761.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human Mdm2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human Mdm2. Next,...
| Schlagworte: | MDM2, Hdm2, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase Mdm2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Human MDM2 (Mdm2 p53 Binding Protein Homolog) ELISA Kit
Artikelnummer: ELK-ELK4557.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MDM2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MDM2. Next,...
| Schlagworte: | MDM2, Hdm2, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase Mdm2,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mdm2 E3 Ligase TR-FRET Kit
Artikelnummer: SBB-KF0030-KI01
South Bay Bio's MDM2 TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto GST-MDM2 in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
| Schlagworte: | MDM2, Hdm2, EC=2.3.2.27, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase... |
| Anwendung: | Enzyme assays |
| Spezies-Reaktivität: | human |
1.433,00 €
Anti-MDM2 Monoclonal Antibody (Clone: SMP14)
Artikelnummer: ABE-36-2760-20
MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor...
| Schlagworte: | Anti-MDM2, Anti-Hdm2, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2, Anti-E3... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 375,00 €
Anti-MDM2
Artikelnummer: ARG51392.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
Anti-phospho-MDM2 (Ser166)
Artikelnummer: ARG51834.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-phospho-Hdm2, Anti-phospho-MDM2, EC=6.3.2.-, Anti-phospho-Oncoprotein Mdm2, Anti-phospho-Double minute 2 protein,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 436,00 €
Anti-phospho-MDM2 (Ser166)
Artikelnummer: ARG54898.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-phospho-Hdm2, Anti-phospho-MDM2, EC=6.3.2.-, Anti-phospho-Oncoprotein Mdm2, Anti-phospho-Double minute 2 protein,... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
662,00 €
Anti-MDM2 (isoform), Internal
Artikelnummer: ARG63943.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-MDM2
Artikelnummer: ARG65770.100
Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1....
| Schlagworte: | Anti-Hdm2, Anti-MDM2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey, mouse |
ab 436,00 €
Anti-MDM2
Artikelnummer: NSJ-R30449
0.5mg/ml if reconstituted with 0.2ml sterile DI water. MDM2 is an important negative regulator of the p53 tumor suppressor. The protein functions both as an E3 ubiquity lipase that recognizes the N-terminal trans-activation domain(TAD) of the p53 tumor suppressor and an inhibitor of p53 transcriptional activation....
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-MDM2
Artikelnummer: NSJ-R33423-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Mouse double minute 2 Protein function: E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and...
| Schlagworte: | Anti-MDM2, Anti-Hdm2, EC=6.3.2.-, Anti-Oncoprotein Mdm2, Anti-Double minute 2 protein, Anti-p53-binding protein Mdm2,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €